| Agent Name | 1,1,1,2-Tetrachloroethane |
|---|---|
| CAS Number | 630-20-6 |
| Formula | C2-H2-Cl4 |
| Major Category | Solvents |
| Synonyms | Ethane, 1,1,1,2-tetrachloro-; 1,1,1,2-Tetrachlorethane; [ChemIDplus] (Chloromethyl) trichloromethane; Asym-tetrachloroethane; F130A; HCC 130A; TCA; [CAMEO] UN1702 |
| Category | Chlorinated Aliphatics |
| Description | Yellowish-red liquid; [NIOSH] Yellow to red liquid; [ICSC] Clear colorless liquid; [NTP] |
| Sources/Uses | Used to make other organic chemicals; [ATSDR ToxFAQs] Used as a solvent; [HSDB] |
| Comments | Target organs are skin, eyes, CNS, and liver. [NIOSH] A skin and eye irritant; May cause CNS effects; [ICSC] An irritant and lachrymator; May cause CNS depression, albuminuria, hematuria, hepatomegaly, jaundice, nephritis, polyneuritis, and skin and eye burns; No evidence of carcinogenicity in mice, equivocal evidence in male rats, and no evidence in female rats; [NTP] An irritant that may cause serious eye injury; Harmful by ingestion and inhalation; Targets the nerves, liver, aned kidney; [Sigma-Aldrich MSDS] See "1,1,2,2-Tetrachloroethane." |
| Restricted | Commercial production has ceased in the U.S. It is still used as a chemical intermediate to synthesize organic chemicals. [ATSDR ToxFAQs] |
| Exposure Assessment | |
| Vapor Pressure | 14 mm Hg |
| Lethal Concentration | LC50 (rat) = 2,100 ppm/4hr |
| Adverse Effects | |
| Lacrimator | Yes |
| Neurotoxin | CNS Solvent Syndrome |
| Hepatotoxin | Hepatotoxin, Secondary |
| IARC Carcinogen | Not Classifiable |
| Links to Other NLM Databases | |
| Health Studies | Human Health Effects from Hazardous Substances Data Bank: |
| Toxicity Information | |
| Chemical Information | |
| Related Information in HazMap | |
| Diseases | Occupational diseases associated with exposure to this agent: |
| Processes | Industrial Processes with risk of exposure: |
Agent Name
1,1,1,2-Tetrachloroethane
CAS Number
630-20-6
Formula
C2-H2-Cl4
Major Category
Solvents
Synonyms
Ethane, 1,1,1,2-tetrachloro-; 1,1,1,2-Tetrachlorethane; [ChemIDplus] (Chloromethyl) trichloromethane; Asym-tetrachloroethane; F130A; HCC 130A; TCA; [CAMEO] UN1702
Category
Chlorinated Aliphatics
Description
Yellowish-red liquid; [NIOSH] Yellow to red liquid; [ICSC] Clear colorless liquid; [NTP]
Sources/Uses
Used to make other organic chemicals; [ATSDR ToxFAQs] Used as a solvent; [HSDB]
Comments
Target organs are skin, eyes, CNS, and liver. [NIOSH] A skin and eye irritant; May cause CNS effects; [ICSC] An irritant and lachrymator; May cause CNS depression, albuminuria, hematuria, hepatomegaly, jaundice, nephritis, polyneuritis, and skin and eye burns; No evidence of carcinogenicity in mice, equivocal evidence in male rats, and no evidence in female rats; [NTP] An irritant that may cause serious eye injury; Harmful by ingestion and inhalation; Targets the nerves, liver, aned kidney; [Sigma-Aldrich MSDS] See "1,1,2,2-Tetrachloroethane."
Restricted
Commercial production has ceased in the U.S. It is still used as a chemical intermediate to synthesize organic chemicals. [ATSDR ToxFAQs]
Exposure Assessment
Vapor Pressure
14 mm Hg
Lethal Concentration
LC50 (rat) = 2,100 ppm/4hr
Adverse Effects
Lacrimator
Yes
Neurotoxin
CNS Solvent Syndrome
Hepatotoxin
Hepatotoxin, Secondary
IARC Carcinogen
Not Classifiable
Links to Other NLM Databases
Toxicity Information
Chemical Information
Related Information in HazMap
Diseases
Occupational diseases associated with exposure to this agent:
Processes
Industrial Processes with risk of exposure: