動脈硬化
Online ISSN : 2185-8284
Print ISSN : 0386-2682
ISSN-L : 0386-2682
高コレステロール食 (卵黄3個+日本茶) 長期常用者における血中リポ蛋白動態について
福生 吉裕小林 陽二中沢 良寿稲葉 治樹渋谷 敏道大塚 博羽田 和正大内 徳行飯島 紘栄赫 彰郎大橋 和史川守田 光雄津島 隆也瀬田 健一新 城之介
著者情報
ジャーナル フリー

1982 年 10 巻 5 号 p. 981-988

詳細
抄録

1) There is a group of people in Japan who make it a habit of drinking a mixture of 3 egg yolkes and green tea (12g) (abbreviated as Egg Tea) which is one of folk remedies. We could get a chance of clinically examining 10 of these people (average year, 60) who had continued on this habit for quite many years (average 21 years). Their Tcho was 213.7mg/dl and T-G, 120.7mg/dl, which were both in their normal ranges. HDL-cho was 74.4mg/dl, atherogenic index (A. I) 2.0, which is low. Besides, their clinical results by ECG and chest XP examinations showed they were scarcely atherosclerotic.
2) In order to confirm the results of I-a), the egg tea was loaded for 3 months to stroke patients who had arrived at stable stage and their lipoprotein methabolism was examined, T-cho tended to rise in the first one month (In A Group who had egg tea 3 times a day, 38mg/dl), after which it reached a plateau and gradually declined. HDL-cho gradually rose (In A group, it revealed to 82mg/dl in the 2nd month) and the increase was dependent to the dose of administration and AT significantly declined in the 2nd month.
-b) Increase in ApoA concentration and LCAT activity was recognized.
-c) Loading of egg alone caused increase of T-cho and HDL-cho and a slight decline tendency of AI.
3) A long-term egg-tea loading coursed suppression of cholesterol synthesis, which worked more specifically strong on LDL-cho and VLDL-cho while HDL-cho was least suppressed. This suggests that in the cholesterol synthesis suppression mechanism the LDL system and HDL system are suppressed through different routes so that possible existence of two suppression pathways was suggested.
4) The fact that the long-time egg tea users had very few atherosclerotic symptoms clinically is considered due to suppression of LDL synthesis leaving HDL synthesis under less suppression so that its high value is maintained.

著者関連情報
© 一般社団法人 日本動脈硬化学会
前の記事 次の記事
feedback
Top