書誌事項
- タイトル別名
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- The Double Blind Test on Chlorhexidine Gluconate Containing Tooth Paste (LS-5) on Periodontal Disease
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抄録
In the experiment conducted this time, an efficacy of a tooth paste containing chlorhexidine-gluconate was evaluated in 24 patients of periodontal disease by the double blind cross-over method as compared with Active control.<br>Scaling was performed just before a medicament was used and at the time a medicament was replaced to new one 2 weeks later in order to evaluate inhibition of plaque and prevention of gingival inflammation.<br>While, a bracket for bacterial testing was installed on the front maxillary teeth when a medicament was used and when a medicament was replaced. As a result, <br>1. There was no difference in an inhibition efficacy of plaque between the two medicaments in the maxillary. However, significant difference was observed in the mandible at the time two weeks passed, and an inhibition efficacy was remarkable in LS-5 group in comparison with OTCAC group.<br>2. In the experiments on an efficacy for prevention of gingival inflammation normal accounting rate with less 3mm, any difference was not observed between the two medicaments in the maxillary.<br>In the mandible, however, LS-5 group showed significant efficacy with respect to improvement of gingival inflammation and periodontal normal accounting rate in comparison with OTCAC group.<br>3. As to the number of bacteria deposited in a piece of TAC film, there was no difference between the two medicaments in an anaerobic bacteria. However, in an inhibition efficacy for proloferation against aeromcrobe, LS-5 group was considered effective in comparison with OTCAC group.<br>4. As a result that scanning electron micro scope was photographed, it was concluded that there was no difference between the two medicaments.<br>5. Evaluation on availability concluded that 75.0 was available in LS-5 group and 50.0% was available in OTCAC group. The comparison between the two medicaments showed significant difference at p=0.041.<br>6. No side effect was observed in each case.
収録刊行物
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- 日本歯周病学会会誌
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日本歯周病学会会誌 25 (4), 955-966, 1983
特定非営利活動法人 日本歯周病学会