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Humane Endpoints



Humane Endpoints
CDROM 'Humane Endpoints in Laboratory Animal Experimentation'
A humane endpoint can be defined as the point at which an experimental animal's pain and/or distress is terminated, minimised or reduced, by taking action such as killing the animal humanely, terminating a painful procedure, or giving treatment to relieve pain and/or distress.
The CD-ROM 'Humane endpoints in laboratory animal experimentation' aims to reduce and prevent pain and distress caused to rodents in research and testing through the education and training of researchers, veterinarians, animal care staff and members of ethics committees about implementation of humane endpoints.
Included on the user-friendly CD-ROM are:
  • Characteristics of healthy mice and rats, including normative values for physiological parameters and normal, aberrant and pain-associated behaviour patterns
  • General clinical signs
  • Specific clinical signs and example score sheets for: cancer research, toxicity studies, vaccine quality control and infectious- and autoimmune disease research
  • Types of humane endpoints and criteria for their development and validation
  • Links to regulations and guidelines pertaining to humane endpoints
  • Interactive self-tests
  • A comprehensive glossary of technical terms
  • Video clips
  • over 100 images
No animals were hurt or killed for the purpose of producing this CDROM.
Only footage from ongoing research was used!
The CD-ROM 'Humane endpoints in laboratory animal experimentation' has been produced through an initiative of the Netherlands Association for Laboratory Animal Science (NVP). The English version of this interactive CDROM is now available on request from the Netherlands Centre Alternatives to animal use. To order, click here. Payment of a voluntary fee is appreciated to cover postage and packing costs.