Abstract
The past year has witnessed refinements in models of spliceosome assembly pathways and in the understanding of how splicing factors of the serine/arginine-rich (SR) protein family function. The role of splicing in human genetic diseases has also received a lot of attention recently as exonic splicing enhancers become better understood.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Animals
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Biological Therapy / methods
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Genetic Variation / genetics
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Humans
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Models, Molecular
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Nuclear Proteins / genetics
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Nuclear Proteins / metabolism*
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RNA Precursors / genetics
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RNA Precursors / metabolism*
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RNA Splice Sites / genetics
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RNA Splice Sites / physiology*
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RNA Splicing / genetics
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RNA Splicing / physiology*
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RNA-Binding Proteins
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Serine-Arginine Splicing Factors
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Spliceosomes / genetics
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Spliceosomes / metabolism*
Substances
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Nuclear Proteins
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RNA Precursors
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RNA Splice Sites
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RNA-Binding Proteins
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Serine-Arginine Splicing Factors