Entry |
|
Name |
Bepotastine (USAN/INN) |
Formula |
C21H25ClN2O3
|
Exact mass |
388.1554
|
Mol weight |
388.8878
|
Structure |
|
Class |
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
|
Remark |
Product (DG01327): | D01654<JP/US> |
|
Efficacy |
Antiallergic, Antipruritic, H1 receptor antagonist |
Comment |
second-generation antihistamine drug
Treatment of ocular itching
|
Target |
|
Pathway |
hsa04080 | Neuroactive ligand-receptor interaction |
|
Interaction |
|
Brite |
Risk category of Japanese OTC drugs [BR:br08312]
First-class OTC drugs
Inorganic and organic chemicals
Bepotastine
D09705 Bepotastine (USAN/INN)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG01327 Bepotastine
D09705 Bepotastine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
HRH1
D09705 Bepotastine (USAN/INN)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG01327 Bepotastine
|
Other DBs |
|
LinkDB |
|
KCF data |
ATOM 27
1 C1c C 21.4577 -23.2474
2 C8y C 20.1907 -23.9513
3 C8y C 22.6543 -23.9513
4 O2a O 21.4577 -21.8396
5 C8x C 20.1907 -25.3591
6 C8x C 18.9941 -23.1770
7 C1y C 22.7247 -21.1357
8 C8x C 18.9237 -26.0630
9 C8x C 17.7975 -23.8809
10 C8y C 17.7975 -25.2887
11 X Cl 16.5305 -25.9926
12 C1x C 23.8510 -21.8396
13 C1x C 25.1180 -21.1357
14 N1y N 25.1180 -19.7984
15 C1x C 23.9214 -19.0945
16 C1x C 22.7247 -19.7984
17 C1b C 26.3146 -19.0945
18 C1b C 27.5112 -19.7280
19 C1b C 28.7782 -19.0241
20 C6a C 29.9748 -19.7280
21 O6a O 31.1714 -19.0241
22 O6a O 29.9748 -21.1357
23 C8x C 22.6543 -25.4295
24 C8x C 23.7806 -26.1334
25 C8x C 25.0476 -25.4295
26 C8x C 25.0476 -24.0217
27 N5x N 23.8510 -23.3178
BOND 29
1 1 2 1
2 1 3 1
3 1 4 1 #Down
4 2 5 2
5 2 6 1
6 4 7 1
7 5 8 1
8 6 9 2
9 8 10 2
10 10 11 1
11 9 10 1
12 7 12 1
13 12 13 1
14 13 14 1
15 14 15 1
16 15 16 1
17 16 7 1
18 14 17 1
19 17 18 1
20 18 19 1
21 19 20 1
22 20 21 1
23 20 22 2
24 3 23 2
25 23 24 1
26 24 25 2
27 25 26 1
28 26 27 2
29 3 27 1
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