Antifungal activity of ajoene derived from garlic

Appl Environ Microbiol. 1987 Mar;53(3):615-7. doi: 10.1128/aem.53.3.615-617.1987.

Abstract

The antifungal activity of six fractions derived from garlic was investigated in an in vitro system. Ajoene had the strongest activity in these fractions. The growth of both Aspergillus niger and Candida albicans was inhibited by ajoene at less than 20 micrograms/ml.

Publication types

  • Comparative Study

MeSH terms

  • Antifungal Agents / pharmacology*
  • Aspergillus niger / drug effects*
  • Aspergillus niger / growth & development
  • Aspergillus niger / ultrastructure
  • Candida albicans / drug effects*
  • Candida albicans / growth & development
  • Candida albicans / ultrastructure
  • Disulfides / pharmacology*
  • Garlic*
  • Microscopy, Electron
  • Microscopy, Electron, Scanning
  • Plant Extracts / pharmacology*
  • Plants, Medicinal*
  • Sulfinic Acids / pharmacology
  • Sulfoxides

Substances

  • Antifungal Agents
  • Disulfides
  • Plant Extracts
  • Sulfinic Acids
  • Sulfoxides
  • allicin
  • ajoene