Welcome to Tumorscape!
This portal is designed to facilitate the use and understanding of high resolution copy number
data amassed from multiple cancer types. The following functionalities are supported:
- Gene-level Analysis:
One can query the level and significance of copy number alterations affecting any
gene listed in Refseq (or miRNAs). Click "Analyses", then "by Gene".
- Analysis by cancer type:
One can query the most significant regions of amplification and deletion in
individual cancer types. Click "Analyses", then "by Cancer Type".
- Download/Browse data:
Data and a user guide to this portal are available for download by
clicking "Browse data" and then "Download". In addition
you can currently browse the full segmented copy-number data using the
Integrated Genomics Viewer
(IGV) by clicking "Analyses", "by Cancer Type",
choosing the dataset you are interested in viewing, and then clicking
the "Peak Region" links under the "Amplifications" or "Deletions" tabs.
For a more detailed description of the methods used to analyze these data, please see
Beroukhim et al, "The landscape of somatic copy-number alteration across
human cancers", Nature, 463:899-905, 2010.