Guillain Barré syndrome and other immune mediated neuropathies: diagnosis and classification

Adi Hersalis Eldar; Joab Chapman

doi:10.1016/j.autrev.2014.01.033

Guillain Barré syndrome and other immune mediated neuropathies: diagnosis and classification

Autoimmun Rev. 2014 Apr-May;13(4-5):525-30. doi: 10.1016/j.autrev.2014.01.033. Epub 2014 Jan 13.

Authors

Adi Hersalis Eldar¹, Joab Chapman²

Affiliations

¹ Department of Neurology, Sheba Medical Center, Sackler Faculty of Medicine, Tel Hashomer, Israel.
² Department of Neurology, Sheba Medical Center, Sackler Faculty of Medicine, Tel Hashomer, Israel; The Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Tel Hashomer, Israel. Electronic address: jchapman@post.tau.ac.il.

PMID: 24434363
DOI: 10.1016/j.autrev.2014.01.033

Abstract

Immune mediated neuropathies are uncommon but important to diagnose because they are potentially treatable. This chapter summarizes the clinical approach to diagnosis of Guillain Barré syndrome (GBS), chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), and related neuropathies which are thought to be caused by direct autoimmune attack on peripheral nerves.

Keywords: Chronic inflammatory demyelinating polyradiculoneuropathy; Guillain Barré syndrome; Multifocal motor neuropathy; POEMS.

Publication types

Review

MeSH terms

Autoantibodies / immunology
Gangliosides / immunology
Guillain-Barre Syndrome / diagnosis*
Guillain-Barre Syndrome / epidemiology
Guillain-Barre Syndrome / immunology
Guillain-Barre Syndrome / therapy
Humans
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / diagnosis*
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / epidemiology
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / immunology
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / therapy
Prognosis
Skin / immunology
Skin / pathology

Substances

Autoantibodies
Gangliosides