Concepts in antibody phage display

Brief Funct Genomic Proteomic. 2002 Jul;1(2):189-203. doi: 10.1093/bfgp/1.2.189.

Abstract

This paper introduces the reader to antibody phage display and its use in combinatorial biochemistry. The focus is on overviewing phage display formats, library design and selection technology, which are the prerequisites for the successful isolation of specific antibody fragments against a diverse set of target antigens.

MeSH terms

  • Antibodies / genetics*
  • Antibodies / immunology
  • Antibody Specificity
  • Bacteriophages / genetics*
  • Quality Control
  • Recombinant Proteins / genetics
  • Recombinant Proteins / immunology

Substances

  • Antibodies
  • Recombinant Proteins