ライフサイエンスコーパス: will

1 , efficient reovirus reverse genetics rescue will accelerate production of recombinant reoviruses as

2 ify driver patterns in ovarian cancer, which will acquire some novel and clinical biomarkers for appr

3 We argue that mesic microenvironments will act as species-specific refugia only if the nature

4 This review will address the functions attributed to cancer exosomes

5 suggesting that environmental heterogeneity will affect large-scale Wolbachia transformations of urb

6 physical flux in natural populations, which will affect the ecology and evolution of infectious dise

7 ity to obtain full PV genomes from FTA cards will aid in facilitating global poliovirus surveillance.

8 tion of the elementary steps of this process will aid the design of new catalytic systems and their r

9 m enabled microfluidic flow-through approach will allow efficient microbial conversion of carbon-cont

10 arieties with relevance for cider production will allow for informed decision making for both apple p

11 he mechanism of long-distance iron signaling will allow improved strategies for the engineering of st

12 ere and provides an electrostatic meter that will allow local electrostatic potential and energetics

13 urgical treatment in individual patients and will allow the comparison of outcome data in future stud

14 It will also be important to align resources and incentives

15 to overcome resistance, but, in the future, will also be the basis for implementing precision cancer

16 Strains identified in this work will also enhance the sensitivity of C. elegans based dr

17 We will also examine how to craft these concepts into tools

18 hat structure variation on recent timescales will also leave similar genomic signatures that reflect

19 This increase in N will also result in a lower S1 energy state, which may p

20 extraordinary lifestyle, and further probing will answer exciting basic microbiological and clinicall

21 In sum, this review will argue that neural-glial interactions represent an i

22 We found that a prefusion intermediate will assemble with HOPS and the R, Qa, and Qc SNAREs, an

23 Last, we will assess whether evidence exists in the literature th

24 We anticipate that this will be a valuable resource to the field of inflammation

25 We believe that BepiPred-2.0 will be a valuable tool for the bioinformatics and immun

26 ndent genetic control suggests that breeders will be able to select semi-independently for mean pheno

27 hromboembolic pulmonary hypertension (CTEPH) will be accelerated by an animal model that replicates t

28 Our findings suggest that the new SFTS model will be an excellent resource to better understand SFTSV

29 rce to the field of inflammation biology and will be an important asset in future anti-inflammatory d

30 aching impacts on the sustainable energy and will be an important research topic in the near future.

31 e late 21st century when climatic conditions will be analogous to the most severe dry/heat spells cau

32 re the current state of knowledge of the NVU will be assessed, focusing on one of its most vital role

33 e proposed method is implemented as in R and will be available an a Bioconductor package.

34 ntly, using AWPM-SG in irrigation scheduling will be beneficial to save more water in areas with shal

35 t by Sc2.0 Consortium teams around the world will be consolidated into a single strain by "endoredupl

36 Potentially, targets will be consumed at 1 M per day per reactor, demanding

37 -inserted state of SecA is still lacking and will be critical for elucidating the bacterial protein t

38 oses a daunting challenge for clinicians but will be critical for the success of disease-modifying th

39 Overall response will be defined as complete response, partial response,

40 described, then individual TORCH infections will be described and compared with the imaging findings

41 findings of congenital infections initially will be described, then individual TORCH infections will

42 ommon cancer among women and 30% of patients will be diagnosed with an ErbB2-positive tumor.

43 en microbes, their metabolites, and the host will be discovered.

44 the basis of these supramolecular materials will be discussed.

45 Critical to enhancing understanding will be disentangling the relative importance of host tr

46 ctivity, therefore downstream dopamine cells will be disinhibited; and thus, this could potentially r

47 shifting from "if it can be done" to "how it will be done." Moving from a theoretical stage to this h

48 Shifts in trophic interactions will be especially important when affecting habitat-form

49 ses in both total and extreme precipitation, will be especially strong for the Northeast and the corn

50 Our flexible Bayesian approach will be especially useful to improve cross-cultural life

51 As of the beginning of 2017, providers will be evaluated on quality and in later years, cost as

52 f these challenges there is a risk that some will be exacerbated.

53 The resource will be extended to >1 million peptides, and all data wi

54 n treating infections caused by MDR bacteria will be heavily influenced by a precision medicine appro

55 tes that successful therapeutic intervention will be highly dependent on the specific therapeutic tar

56 This will be important in predicting extrusion hotspots and d

57 lecules, only sunlight and fluorescent tubes will be important to room-averaged indoor HOx levels due

58 lic vectors, existing vector control tactics will be insufficient to achieve elimination, even if max

59 tudies in atomic and molecular chains, which will be key to investigating numerous fundamental issues

60 Important allergic disorder associations will be missed without subgroup analyses.

61 recipient factors, based on local data sets, will be more beneficial in the Australian context.

62 f disease-causing host-parasite interactions will be more clearly understood through a focus on disea

63 Significant preparation will be needed for a thorough, synchronized, and full wi

64 ovel immunotherapies and combinations likely will be needed for most subtypes.

65 Further studies will be needed to assess possible herd immunity effects

66 95% uncertainly interval [UI], 55.2 to 60.0) will be obese at the age of 35 years, and roughly half o

67 data suggest that pheromone-based technology will be of global utility for the monitoring of this imp

68 oral multiplex networks and we anticipate it will be of interest to researchers in a broad array of f

69 This will be of potential use for monitoring HD mouse model d

70 sion and predicts that type I IFN modulation will be pivotal to cure human chronic infections, cancer

71 his Perspectives article, these new insights will be placed in the context of previously unresolved i

72 r results suggest that coffee-suitable areas will be reduced 73-88% by 2050 across warming scenarios,

73 h changes in terrestrial water storage (TWS) will be reflected in the water contained in the ocean an

74 perties obtained under idealized assumptions will be reported separately.

75 International collaboration will be required to perform clinical studies to inform t

76 r from the non-permanence risk that stored C will be returned to the atmosphere.

77 ne whether this class of potential therapies will be safe and effective for individuals with retinal

78 us predict that tropical coastal communities will be seriously endangered as the global sea level ris

79 xtended to >1 million peptides, and all data will be shared with the community via ProteomicsDB and P

80 e elements with similar retention mechanisms will be similarly affected by climate change.

81 rrently subjected to warm and dry conditions will be the most vulnerable in the late 21st century whe

82 These guidelines will be updated periodically as more evidence becomes av

83 her, these results indicate that this system will be useful for functional and gene expression studie

84 These results will be useful for vector selection for various applicat

85 ing hydrogen sulfide, perthiol, and COS, and will be very useful as part of the toolbox for delineati

86 s by clinicians, nurses, and patients, which will be vital in ensuring viral load tests are appropria

87 ible molecular knot topologies increases, it will become increasingly useful for chemists to adopt th

88 biomarkers that predict which mRCC patients will benefit from antiangiogenic therapy.

89 history is critical to identify families who will benefit from genetic testing, determine the best st

90 on of biomarkers that predict which patients will benefit from these therapies.

91 m strategy will create a network effect that will benefit multiple disease programs.

92 lar imaging would help identify patients who will best respond to anti-PD-L1 treatment while potentia

93 hat by 2030, national female life expectancy will break the 90 year barrier, a level that was deemed

94 sses, as the consequences on their abundance will cascade throughout the food web.

95 ntial of high-performance nanomaterials that will cause disruptive improvements in the field of biose

96 Our models predict that climate change will considerably reduce establishment of a currently pr

97 chemotherapy and ongoing randomised studies will continue to aim to optimise treatment for high-risk

98 Finally a perspective on how this field will continue to evolve is provided.

99 th cohorts in diverse environments worldwide will continue to provide critical knowledge about the fa

100 study into this interesting set of compounds will continue to provide insights into fundamental quest

101 These efforts will contribute to a more complete understanding of glob

102 ating these species instead of Norway spruce will contribute to maintaining a high level of productiv

103 Biosensors will contribute to the 4th revolution in agriculture by

104 on the disordered vanadium oxide nanosheets will contribute to the exploration of disordered structu

105 This Review is organized by metal and will cover work published from late 2009 until mid-2016.

106 A platform strategy will create a network effect that will benefit multiple

107 iciency comparing several mouse models, that will deepen our understanding, open avenues for research

108 We anticipate that this study will demonstrate that idiopathic DCM has a genetic basis

109 The urgency of the transition will depend largely on the country-specific prevalence o

110 Improving outcomes will depend on a multifaceted approach, including correc

111 The appropriate strategy will depend on characteristics of the sample, the sequen

112 The costs associated with this legislation will depend on how actors in the food value chain respon

113 ectron spins as qubits for quantum computing will depend on the ability to produce molecules with wea

114 their effect on subsequent guideline updates will depend on the methodology and evidence model used b

115 This article will describe the past decade of work toward this goal a

116 and the other in late protocol development) will determine the clinical efficacy of fosfomycin as st

117 Up to one third of individuals with NAFLD will develop nonalcoholic steatohepatitis (NASH), which

118 ants encountering strong westerly crosswinds will diminish.

119 nal microbiota and the immune system, and we will discuss how a dietary-induced disruption of the int

120 In this review, we will discuss recent progress made in the field of functi

121 sibly identifying peripheral biomarkers that will eliminate the need for scalp biopsies.

122 SEQSpark will empower large sequence-based epidemiological studie

123 ng numerical solutions for insolation, which will enable a more precise and accurate geological times

124 This synthetic system will enable detailed, mechanistic dissection of MCC gene

125 model of depth-integrated, daily production will enable efficient global predictions of picophytopla

126 This work will enable future efforts in developing highly efficien

127 However, identifying distinct responses will enable novel routes for PTP-selective drug design,

128 The experimental techniques reported here will enable thermal transport studies in atomic and mole

129 ment of common postoperative conditions they will encounter as new surgical interns.

130 elivery could exceed US$30 billion, and this will encourage researchers to study the application of N

131 k of the desire to control when and how life will end.

132 The ICHOM will endeavor to achieve wide buy-in of this set and fac

133 nderstanding of this differential regulation will enhance efforts to improve oilseed rape productivit

134 These false assignments will eventually lead to wrong conclusions on the structu

135 Building on this success, CRACKLE II will expand the network to hospitals across the United S

136 Nearly all older men will experience lower urinary tract symptoms associated

137 Future studies will explore methods to reduce kidney activity retention

138 models project that subalpine forest ranges will extend upslope with climate warming.

139 r convergence and building blocks of CAM and will facilitate CAM-into-C3 photosynthesis engineering t

140 ce, and analyses of treatment mediators that will facilitate further therapeutic development.

141 genetic correlation among complex traits and will facilitate future soybean functional studies and br

142 Thus, FlpStop will facilitate investigations into the interactions bet

143 n vivo and in ex-vivo tissue sections, which will facilitate mRNA trafficking studies in pre-clinical

144 ur assembly method is readily accessible and will facilitate the construction of sophisticated materi

145 ng of the mechanism of this efficient enzyme will facilitate the development of synthetic molecular c

146 dy provides crucial insights into RIBEs, and will facilitate the identification of additional RIBE fa

147 and weaker affinity with SnI2 than FA+ ions will facilitate the intramolecular exchange with FA+ ion

148 ions occurring in close temporal proximity - will favor populations that would otherwise have an aver

149 e believe our results and simulation methods will find applications in many different contexts.

150 In this review article, we will first review the key role of Ca(2+) in normal cardi

151 This review will focus on the current knowledge for the main subclas

152 ients is warranted, and as such, this review will focus on the incidence, surveillance, and treatment

153 This review will focus on the role of cell death in maintenance of T

154 Whereas another review will focus on the role of Runx factors in leukemias, thi

155 pective measurements of peripouch fat, which will foster future investigation of the role of mesenter

156 the influence of early and midlife exposures will further advance our understanding of the disease.

157 diverse biological systems and tissue types will further improve our understanding of ancient DNA br

158 This review will give an overview of the presentation, evaluation, a

159 An ideal observer will give equivalent weight to sources of information th

160 This platform will greatly benefit both researchers and clinicians for

161 l phenomena is that of straightness - a root will grow down, a petal will grow flat.

162 traightness - a root will grow down, a petal will grow flat.

163 are not intended as fixed depictions of what will happen.

164 ating syndrome of the central nervous system will have a monophasic disease course, with no further c

165 s of mutation-dependent drug response, which will have a significant impact on cancer precision medic

166 imization of high-energy-storage dielectrics will have far-reaching impacts on the sustainable energy

167 t the end of the experiment some metabolites will have incorporated the labelling isotope, to a degre

168 is an example of the impact that 3D-printing will have on the future of analytical device fabrication

169 therefore hypothesized that IL-15(-/-) mice will have reduced inflammatory responses during the deve

170 at cancer cells that survive treatment still will have suffered cytotoxic stress and thereby enter a

171 ere improving the resolution of climate data will have the largest impact on the accuracy of biologic

172 Abeta1-42 level is an important finding that will have to be replicated in other cohorts.

173 to metabolite data, we hope that this system will help enable data sharing and reanalysis in the meta

174 This model will help further discover the pathomechanisms of this d

175 This and similar approaches will help identify additional intermediates during CCC D

176 These studies will help identify novel treatment strategies.

177 survival and differentiation of repair cells will help identify, and eventually correct, the failures

178 implications of distinct cell death pathways will help in the development of therapeutic intervention

179 the impact of different risk factors, which will help in understanding the development of obesity in

180 Our results will help permit the rational design of complex new mole

181 This paper will help researchers to better design spin trapping exp

182 These data will help to prioritize future research directions.

183 The C5aR2 knock-in mouse will help to reliably track and conditionally delete C5a

184 This group of rare designed hexasaccharides will help understand HCII function.

185 We will here review key findings that have elucidated the c

186 l in predicting severity of illness but also will hopefully allow for identification of the disease p

187 elevant targets in neoplastic mast cells and will hopefully receive recognition by health authorities

188 This research will impact our understanding of morbillivirus-related i

189 act of dehydration and electrolyte imbalance will improve health outcomes.

190 ons into FRED to fill gaps in trait coverage will improve our understanding of changes in fine-root t

191 counting for Allee effects in social species will improve our understanding of the ecological and evo

192 sociated SNPs and the regulatory genome that will improve the functional interpretation of non-coding

193 e basis for further experimental work, which will in turn provide input to refine and develop the mod

194 ation processes and implementation protocols will increase access to wireless optofluidic neural prob

195 The hazard of dropout will increase from 41% to 46% nationally.

196 , and the median age of the NAFLD population will increase from 50 to 55 years during 2015-2030.

197 est that comprehensive WGS-based SV analyses will increase the power of common- and rare-variant asso

198 ectors are added to the ECF based cells that will increase the total weight of devices.

199 llary is that in a globalizing world, wealth will inevitably be appropriated by a very small fraction

200 HF, OFT and HM development in zebrafish that will inform mechanistic interpretations of cardiopharyng

201 These results will inform the rational development of 2D COF polymeriz

202 g users to build intuition and insights that will inform their experimental strategy.

203 , knowing how different species' metabolisms will integrate to reach a desired outcome is a difficult

204 Interventions that target these events will interrupt tuberculosis transmission and accelerate

205 imental validation, predict that rare fixers will invade a population dominated by non-fixing bacteri

206 ey expect the diagnostic information yielded will lead to better patient care, enhanced patient safet

207 Resolving these three issues will lead to better, more replicable, and more useful so

208 that combined, elevated CO2 and temperature will lead to long-term declines in the amount of carbon

209 Validating these associations in vivo will lead to new diagnostic tools for Alzheimer disease

210 hanisms that acutely affect DAT availability will likely exert significant impact on both normal and

211 to program therapeutic cells, so our methods will likely facilitate manufacturing of cytoreagents.Cur

212 for nonelderly Americans, private insurance will likely play a major role.

213 years with substantial care needs, and most will live in the community.

214 rated fats, especially polyunsaturated fats, will lower the incidence of CVD.

215 Future regulatory design will minimize compliance costs and HEC tradeoffs by regu

216 nd grain filling using donors such as NL-44, will minimize the negative impact of heat stress and inc

217 f sea-level rise expected no later than 2050 will more than double the frequency of extreme water-lev

218 g programs and create new opportunities that will move us closer to the vision of achieving an oncolo

219 ven if observers are certain that the object will move.

220 Health policy in Afghanistan will need to address attitudinal, social, and accessibil

221 ven if successful, however, these approaches will need to be combined with additional complementary a

222 taken, there are substantial obstacles that will need to be overcome if CRISPR-Cas9 is to be used in

223 ul mitigation efforts in the Red Deer region will need to focus on the >90% of methane emissions curr

224 to elevated circulating E2 Collectively, we will need to modify the concept of estrogen's positive f

225 However, extant plant trait distributions will not allow extrapolations to novel community assembl

226 ith pharmacoresistant temporal lobe epilepsy will not be rendered completely seizure-free after tempo

227 antially increased resolution of gene models will not only further our understanding of the biologica

228 detailed understanding of these interactions will not only provide improved treatment options to over

229 tion of polyadenylated RNA via oligo(dT), it will not provide RNA-binding information on proteins int

230 ge in forest or wetland biomass or soil, and will not suffer from the non-permanence risk that stored

231 ough finite temperature equilibrium dynamics will not yield hyperuniform states, driven, nonequilibri

232 nthesis of a protein to ensure that an event will occur at a precise time, while minimizing deviation

233 and roughly half of the projected prevalence will occur during childhood.

234 Most of these extinctions will occur over an extended time, and therefore, reconne

235 patients with CVID with immune dysregulation will offer new therapeutic avenues for this subgroup.

236 ion of Oldowan zooarchaeological assemblages will only be accurately revealed by better bounding equi

237 nd their chemical versatility for adaptation will open new opportunities for applications built upon

238 s), the integrated cheminformatics algorithm will optimize the extracted biological data using in vit

239 and recent data suggest that only about 50% will outgrow by age 8.

240 MSM not attending GUM clinics will partially benefit from herd protection.

241 dy suggest these phenolic and nitro-aromatic will partition into the condensed state for a wide range

242 o increased cardiovascular (CV) risk in PTSD will pave the way for developing interventions to improv

243 unities afforded by supramolecular chemistry will play a vital role in the future of the drug deliver

244 It is likely that TAVR will play an increasingly important role in the manageme

245 fore pain modulatory systems reach maturity, will predict pronounced changes in thalamic development,

246 We will present herein an overview of the interactions occu

247 te that the population of sub-Saharan Africa will probably lose 2.3 million disability-adjusted life-

248 Moving forward, answers to these questions will provide a greater level of understanding of miRNA b

249 ental concerns, we anticipate that this work will provide a standardized baseline for future work to

250 Our coherence control technique will provide a unique solution for a low-speckle, full-f

251 We expect the method will provide a useful tool for the molecular study of co

252 le of Runx factors in leukemias, this review will provide an overview of the normal regulation and fu

253 viruses evade or exploit macrophage function will provide greater insight into viral pathogenicity an

254 y of ancient plant populations and, in time, will provide higher taxonomic resolution and more precis

255 ncology or imaging guideline recommendations will provide increased value or cause increased distress

256 Further expansion of this study will provide more insight into the long-term safety and

257 rstanding age-related changes to the UPR(ER) will provide new avenues for therapeutic intervention in

258 lating plasma proteins (the plasma proteome) will provide opportunities for unbiased discovery of nov

259 This review will provide readers with an updated vision of current a

260 erventions are being tested, which hopefully will provide translational insights to stop the growing

261 Future work will reassess these estimates in light of more clinical

262 those with HER2 and ER negative tumors, who will receive one of the widely-accepted chemotherapy reg

263 t's wishes; the family is too distressed and will regret the decision; overruling harms other patient

264 munity assemblages in future climates, which will require a mechanistic understanding of the trade-of

265 Elucidating cerebellar function will require an understanding of the interactions, both

266 des, extending those made in recent decades, will require continued research into mechanisms underlyi

267 alternative programs, comparison of results will require general agreement on definitions of respons

268 ultimate success of immunotherapy in the CNS will require improved imaging technologies and methods f

269 This process will require new skills and education in systems science

270 ration of the brain's vast synaptic networks will require new tools for high-throughput structural an

271 These findings will require rethinking of how this class of endosomal p

272 agnosis and treatment for all people with TB will require simpler, more sensitive diagnostics and bro

273 preservation of average post-transplant eGFR will require sustained improvement in immunosuppression

274 (ART) to eliminate pediatric HIV-1 infection will require the characterization of maternal immune res

275 gh-density, low-power neuromorphic computing will require very large numbers of nanoscale nonlinear o

276 ormation for use in predicting how a patient will respond to a given proposed drug or treatment.

277 key to understanding how animal populations will respond to changing climatic conditions.

278 efit from fire, it is unknown how ecosystems will respond to increased burning and warming.

279 Delays in dosing time will result in transient periods of lower concentrations

280 nsformation over time along these dimensions will reveal how the nature of language reflects human mi

281 These studies will serve as a starting point to explore the nonlinear

282 peutics to clear persistently infected cells will soon allow measurable clinical advances toward an H

283 We anticipate that our results will spark renewed investigation in modulating the funct

284 e that this conceptual mechanistic framework will stimulate fruitful research that aims at unraveling

285 Our models predict that cell shape will strongly influence the fate of a cell lineage: we d

286 This review will summarize recent advances in dissecting the relativ

287 tion by testing whether a preconditioned cue will support conditioned reinforcement in rats.

288 ding population immunity to transmission and will sustain transmission as long as they do not attain

289 ned from minute patient-derived samples, and will therefore potentially allow the identification of c

290 epresents around 4% of the final product, it will therefore strongly influence the elemental and isot

291 icted the duration of time that viewers were willing to commit to narrative videos.

292 ggesting that one-third of patients might be willing to donate at imminent death, we estimate that be

293 of Wisconsin would be medically eligible and willing to donate each year at the time of imminent deat

294 sis, and offers hope that similar approaches will transform the management of patients with other pro

295 te a more accurate arrival-time picking that will ultimately improve the localization accuracy.

296 approaches are tackling these challenges and will ultimately serve as an engine for biological discov

297 owledge of these viral proteins improves, we will undoubtedly uncover how the multifunctional nature

298 The optimal decision will vary in different social-ecological contexts, but s

299 close kin and that this gap in availability will widen in the coming decades.

300 e the nonlinear dynamics of atrial cells and will yield insights into the trigger and maintenance of