ライフサイエンスコーパス: traumatic

1 r cancer is highly stressful and potentially traumatic.

2 t ICH events were spontaneous (71.7%) versus traumatic (28.3%).

3 inflammatory mediators and inhibits the post-traumatic activation of JNK in a rodent model of TBI.

4 Using traumatic and vincristine-induced injury models in neuro

5 ence of IL-1 signaling as a mediator of post-traumatic astrogliosis and seizure susceptibility.SIGNIF

6 y MHC-II on Schwann cells thus promotes post-traumatic axonal loss and neuropathic pain.

7 noncalcium (VNCa) technique for detection of traumatic bone marrow edema in patients with vertebral c

8 ts interpreted virtual noncalcium images for traumatic bone marrow edema.

9 sm (VTE) prophylaxis in patients with severe traumatic brain injuries (TBI).

10 The long-term clinical effects of wartime traumatic brain injuries (TBIs), most of which are mild,

11 quantify benefits of hypothermia therapy for traumatic brain injuries in adults and children by analy

12 a is likely a beneficial treatment following traumatic brain injuries in adults but cannot be recomme

13 time with brain tissue hypoxia after severe traumatic brain injury (0.45 in intracranial pressure-on

14 Mild blast traumatic brain injury (B-TBI) induced lasting cognitive

15 ) 10 years and older with moderate or severe traumatic brain injury (Barell Matrix Type 1 classificat

16 in injury and 32 patients with isolated mild traumatic brain injury (comparison group) was assessed w

17 racic echocardiogram within 1 day after mild traumatic brain injury (comparison group).

18 -channel head coil from each of 3 concussive traumatic brain injury (cTBI) patients and 4 controls tw

19 nsecutive children (age < 18 yr) with severe traumatic brain injury (Glasgow Coma Scale </= 8; intrac

20 ndred three patients with moderate or severe traumatic brain injury (Glasgow Coma Scale, 3-13).

21 appropriate treatment of children with mild traumatic brain injury (mTBI) and intracranial injury (I

22 it remains unknown the extent to which mild traumatic brain injury (mTBI) may impact these critical

23 nces (P < 0.0001); 11.1% to 26.0% for severe traumatic brain injury (P < 0.0001), and 4.7% to 5.9% fo

24 of complex partial seizures (CPSs) following traumatic brain injury (post-traumatic epilepsy).

25 with cognitive fatigue between persons with traumatic brain injury (TBI) and healthy controls (HCs).

26 after injury and determine the influence of traumatic brain injury (TBI) and massive transfusion on

27 Studies of the association between traumatic brain injury (TBI) and suicide attempt have yi

28 ually, there are over 2 million incidents of traumatic brain injury (TBI) and treatment options are n

29 Traumatic brain injury (TBI) can have lifelong and dynam

30 Traumatic brain injury (TBI) can induce cognitive dysfun

31 Traumatic brain injury (TBI) causes extensive neural dam

32 Traumatic brain injury (TBI) contributes to one third of

33 Traumatic brain injury (TBI) increases the risk of Alzhe

34 The impact of traumatic brain injury (TBI) involves a combination of c

35 Traumatic brain injury (TBI) is a leading cause of long-

36 Traumatic brain injury (TBI) is a leading cause of morbi

37 Traumatic brain injury (TBI) is a major contributor to m

38 Traumatic brain injury (TBI) is a major public health is

39 Traumatic brain injury (TBI) is a serious public health

40 Traumatic brain injury (TBI) is a significant global pub

41 Epilepsy after pediatric traumatic brain injury (TBI) is associated with poor qua

42 Traumatic brain injury (TBI) is characterized by acute n

43 Traumatic brain injury (TBI) is currently a major cause

44 Traumatic brain injury (TBI) is extremely common across

45 Traumatic brain injury (TBI) is known to cause perturbat

46 Traumatic brain injury (TBI) is set to become the leadin

47 ry deficits after TBI.SIGNIFICANCE STATEMENT Traumatic brain injury (TBI) is the leading cause of dea

48 ession involved in the MQC in rats receiving traumatic brain injury (TBI) of different severities.

49 a controlled cortical impact model (CCI) of traumatic brain injury (TBI) on their distribution.

50 sregulation of pathways directly involved in traumatic brain injury (TBI) pathogenesis and have been

51 etection of neuron-specific enolase (NSE), a traumatic brain injury (TBI) protein biomarker, in dilut

52 Traumatic brain injury (TBI) results in rapid recruitmen

53 ipoprotein E4 (ApoE4) genotype combines with traumatic brain injury (TBI) to increase the risk of dev

54 usly been shown to occur in animal models of traumatic brain injury (TBI), and blocking this form of

55 Brain damage due to stroke or traumatic brain injury (TBI), both leading causes of ser

56 eater risk of Parkinson's disease (PD) after traumatic brain injury (TBI), but it is possible that th

57 g is a mainstay of therapy for children with traumatic brain injury (TBI), but its overall associatio

58 After traumatic brain injury (TBI), glial cells have both bene

59 PSH has predominantly been described after traumatic brain injury (TBI), in which it is associated

60 Following traumatic brain injury (TBI), ischemia and hypoxia play

61 ngth and learning, is dysregulated following traumatic brain injury (TBI), suggesting that stimulatio

62 After traumatic brain injury (TBI), the ability of cerebral ve

63 trocytes to fluid shear stress in a model of traumatic brain injury (TBI), we found that shear stress

64 ri-lesional brain and white matter following traumatic brain injury (TBI).

65 r of ER stress, which has been implicated in traumatic brain injury (TBI).

66 t potentially underdiagnosed complication of traumatic brain injury (TBI).

67 l changes following traumatic spinal cord or traumatic brain injury (TBI).

68 t and chronic traumatic encephalopathy after traumatic brain injury (TBI).

69 in cerebral energetic metabolism arise after traumatic brain injury (TBI).

70 (beta)-blockers improve outcomes after acute traumatic brain injury (TBI).

71 ic disorders including Alzheimer disease and traumatic brain injury (TBI).

72 ecific outcome measure (clinically important traumatic brain injury [TBI], need for neurological inte

73 Seven (22%) moderate-severe traumatic brain injury and 0 (0%) mild traumatic brain i

74 in 32 patients with isolated moderate-severe traumatic brain injury and 32 patients with isolated mil

75 n hospital including 6516 (78%) after severe traumatic brain injury and 749 (9%) after severe thoraco

76 This study examined mild traumatic brain injury and genetic risk as predictors of

77 oderated mediation analysis showed that mild traumatic brain injury and high genetic risk indirectly

78 l thickness, such that individuals with mild traumatic brain injury and high genetic risk showed redu

79 le in human cerebrospinal fluid after severe traumatic brain injury and is an informative biomarker o

80 its potential to guide targeted therapies in traumatic brain injury and other diseases involving cere

81 ages of 19 and 58, many of whom carried mild traumatic brain injury and post-traumatic stress disorde

82 t develops following brain injuries, such as traumatic brain injury and stroke, and is often associat

83 e oxygenation levels in patients with severe traumatic brain injury and the feasibility of a Phase II

84 n trauma systems, assess the contribution of traumatic brain injury and thoracoabdominal injury to ob

85 Treatment of secondary injury after severe traumatic brain injury based on brain tissue oxygenation

86 vitrectomy for Terson syndrome secondary to traumatic brain injury between 1997 and 2015.

87 s intracranial hypertension in patients with traumatic brain injury but was associated with harm in t

88 We examined variation in treatment for traumatic brain injury by assessing factors influencing

89 Traumatic brain injury due to blast exposure is currentl

90 ren with abusive head trauma from those with traumatic brain injury from other mechanisms.

91 Current prehospital traumatic brain injury guidelines use a systolic blood p

92 xygenation and poor outcome following severe traumatic brain injury has been reported in observationa

93 pilepsy is a common cause of morbidity after traumatic brain injury in early childhood.

94 Management of severe traumatic brain injury informed by multimodal intracrani

95 Traumatic brain injury is a major cause of death and dis

96 These results provide evidence that mild traumatic brain injury is associated with greater neurod

97 sue oxygenation-directed treatment of severe traumatic brain injury is warranted.

98 Prior studies have suggested that traumatic brain injury may affect cardiac function.

99 non-auditory effects of blast and potential traumatic brain injury may also exert an effect.

100 Patients with acute severe traumatic brain injury may recover consciousness before

101 lgals-1(-/-) mice to develop spinal cord- or traumatic brain injury models for the evaluation of the

102 Results showed that mild traumatic brain injury moderated the relationship betwee

103 le for meta-analysis were from patients with traumatic brain injury or subarachnoid hemorrhage.

104 nylurea receptor-1 was present in all severe traumatic brain injury patients (mean = 3.54 +/- 3.39 ng

105 Data from 729 severe traumatic brain injury patients admitted between 1996 an

106 Adult traumatic brain injury patients admitted to intensive ca

107 evere traumatic brain injury and 0 (0%) mild traumatic brain injury patients had systolic dysfunction

108 nsor imaging abnormalities in a cohort of 97 traumatic brain injury patients were also mapped at the

109 orts of recently treated adult and pediatric traumatic brain injury patients.

110 sion pressure threshold management in severe traumatic brain injury patients.

111 0 minutes in advance, in adult and pediatric traumatic brain injury patients.

112 One hundred nineteen severe traumatic brain injury patients.

113 fluid samples were collected from 28 severe traumatic brain injury patients.

114 f systolic dysfunction among moderate-severe traumatic brain injury patients.

115 Unlike other traumatic brain injury populations in children, female p

116 nsecutive patients undergoing CT imaging for traumatic brain injury recruited between January and Oct

117 to the intensive care unit for acute severe traumatic brain injury to test two hypotheses: (i) in pa

118 Approaches and Decisions in Acute Pediatric Traumatic Brain Injury Trial-a comparative effectiveness

119 y or Glasgow Outcome Scale for patients with traumatic brain injury were the pressure reactivity inde

120 MRI following traumatic brain injury yields important prognostic infor

121 rove long term functional outcomes following traumatic brain injury(TBI).

122 , including (1) reducing SICU care for minor traumatic brain injury, (2) optimizing postoperative air

123 tive diseases and cognitive impairment after traumatic brain injury, all hallmarked by the accumulati

124 iously healthy patients with moderate-severe traumatic brain injury, and it is reversible over the fi

125 o the brain in mouse models of glioblastoma, traumatic brain injury, and Parkinson's disease.

126 brain, has recently been linked to sleep and traumatic brain injury, both of which can affect the pro

127 In patients with traumatic brain injury, ESA therapy did not increase the

128 The major cause of delayed surgery was traumatic brain injury, followed by facial or orbital fr

129 ssment included history of playing rugby and traumatic brain injury, general and mental health, life

130 Among males with mild traumatic brain injury, high genetic risk for Alzheimer'

131 nogenesis, stroke, intracerebral hemorrhage, traumatic brain injury, ischemia-reperfusion injury, and

132 troke, AD, age-related macular degeneration, traumatic brain injury, Parkinson's disease, and other n

133 ribed glymphatic system has been linked with traumatic brain injury, prolonged wakefulness, and aging

134 Thus, in patients with traumatic brain injury, the concept that 90 mm Hg repres

135 creasingly used in the early phase following traumatic brain injury, the prognostic utility of MRI re

136 microglia in models of stroke, infection and traumatic brain injury, though the exact role of the imm

137 are still considered the most lethal type of traumatic brain injury.

138 terns for discriminating clinical outcome in traumatic brain injury.

139 the acute phase following moderate or severe traumatic brain injury.

140 omy for intraocular hemorrhages secondary to traumatic brain injury.

141 rebral edema is a key poor prognosticator in traumatic brain injury.

142 rising from neurodegenerative disease and/or traumatic brain injury.

143 dysfunction in patients with moderate-severe traumatic brain injury.

144 omy for intraocular hemorrhages secondary to traumatic brain injury.

145 y mechanical impact in a mouse model of mild traumatic brain injury.

146 Canadian provinces, specifically for severe traumatic brain injury.

147 ma are serious complications of ischemic and traumatic brain injury.

148 tical function in patients with acute severe traumatic brain injury.

149 teractions between four treatments following traumatic brain injury.

150 inuous variable (p = 0.07) for patients with traumatic brain injury.

151 sive care who had suffered a primary, closed traumatic brain injury; increased intracranial pressure;

152 nd over the first week after moderate-severe traumatic brain injury; transthoracic echocardiogram wit

153 rognosis and Analysis of Clinical Trials in [Traumatic Brain Injury] (IMPACT) extended model sum scor

154 plays key roles in the repair process after traumatic brain lesions.

155 To determine whether delayed repair of traumatic canalicular laceration affects the final outco

156 ecords of 334 patients who underwent primary traumatic canalicular laceration repair were retrospecti

157 al rates remain low after hemorrhage-induced traumatic cardiac arrest (TCA).

158 his large animal model of hemorrhage-induced traumatic cardiac arrest with NCTH.

159 dsagittal tissue bridges at the epicenter of traumatic cervical spinal cord lesions in 24 subacute te

160 onscious state with language (n = 4) or post-traumatic confusional state (n = 4).

161 After traumatic cutaneous inoculation, several fungi can cause

162 ion of the spinal cord and formation of post-traumatic cysts.

163 , as were 24 cases with a clear diagnosis of traumatic death before investigation; 210 cases were inc

164 Ophthalmoplegia secondary to a traumatic dissecting aneurysm in the cavernous segment o

165 d associated with the development of chronic traumatic encephalopathy (CTE) and Alzheimer's disease.

166 ade with the more recently described chronic traumatic encephalopathy (CTE).

167 eurological conditions, particularly chronic traumatic encephalopathy (CTE).

168 e of acute neurologic impairment and chronic traumatic encephalopathy after traumatic brain injury (T

169 Chronic traumatic encephalopathy can occur after sporting injuri

170 cations, where pathology in cases of chronic traumatic encephalopathy is observed.

171 o central to Alzheimer's disease and chronic traumatic encephalopathy, a successful tau therapeutic f

172 ase, progressive supranuclear palsy, chronic traumatic encephalopathy, and other tauopathies.

173 europathology is prominently seen in chronic traumatic encephalopathy, and whether human neuroimaging

174 alsy, corticobasal degeneration, and chronic traumatic encephalopathy, but did not label nonpathologi

175 isk of the neurodegenerative disease chronic traumatic encephalopathy.

176 bed as polypathology, which includes chronic traumatic encephalopathy.

177 are common causes of post-operative and post-traumatic endophthalmitis.

178 This study aimed to characterize post-traumatic epilepsy in a mouse model of pediatric brain i

179 ays model heritable absence epilepsy or post-traumatic epilepsy in humans, and may instead reflect ty

180 CPSs) following traumatic brain injury (post-traumatic epilepsy).

181 as to whether biological sex and the type of traumatic event influence shared or distinct biological

182 traumatic stress disorder (PTSD) following a traumatic event.

183 ssociation between pre-migration potentially traumatic events and mental health after controlling for

184 Pre-migration potentially traumatic events and post-migration stressors related to

185 Pre-migration potentially traumatic events and post-migration stressors were posit

186 pre-migration and post-migration potentially traumatic events and stressors and mental health, and as

187 eory offer a framework for understanding how traumatic events can lead to a range of behaviors associ

188 The natural aging process and traumatic events such as lower-limb loss can alter the h

189 The mean number of pre-migration potentially traumatic events was 2.1 (SD 1.4).

190 Considering the effect of traumatic experience on post-traumatic stress disorder (

191 del certain behavioral traits resulting from traumatic experiences in humans.

192 Individuals respond differently to traumatic experiences, including their propensity to dev

193 ling) reduces emotional distress after other traumatic experiences.

194 isms underlying depression and anxiety after traumatic experiences.

195 We report the findings of an individual with traumatic high-cervical spinal cord injury who coordinat

196 al-energy CT for suspicion of a nondisplaced traumatic hip fracture.

197 ensitivity for the detection of nondisplaced traumatic hip fractures and improved diagnostic confiden

198 Traumatic implantation of contaminated plant material is

199 frica and South and Central America, follows traumatic implantation of saprophytic fungi and frequent

200 ed fracture healing because of systemic post-traumatic inflammation.

201 Widely different traumatic injuries evoke surprisingly similar gene expre

202 ransplantation strategies in a wide range of traumatic injuries for which therapeutic intervention is

203 ansplantation strategies for a wide range of traumatic injuries is the determination of a suitable ti

204 taneously or after provoking events, such as traumatic injuries to the pelvis, upper and lower exterm

205 death caused by demyelinating, ischemic, and traumatic injuries, implying its involvement in a wide s

206 HO) after blast-related extremity injury and traumatic injuries, respectively.

207 damage and can be reversible in ischemic and traumatic injuries.

208 juries and contusion or occult fracture) for traumatic injuries.

209 sed interventions to regenerate large scale, traumatic injuries.

210 evel decision that affects how patients with traumatic injury (trauma patients) interact with locoreg

211 [SD, 16.2]; men, 197 [61%]; had experienced traumatic injury after a fall, 223 [69%]), 258 completed

212 entral nervous system axons, associated with traumatic injury and demyelinating diseases such as mult

213 inical research on cellular therapeutics for traumatic injury and its sequelae and discuss prospects

214 nrolled 1138 patients recently admitted with traumatic injury to 1 of 4 major trauma hospitals across

215 , we first demonstrate that a mouse model of traumatic injury to the pediatric brain reproduces many

216 The moderate and mild traumatic injury was inflicted by focal laser lesion and

217 al interventions can now be applied to treat traumatic injury, David J Lockey calls for research to d

218 ndrome and delirium tremens in patients with traumatic injury.

219 munocompromised patients or individuals with traumatic injury.

220 also detect "danger" signals (pathogenic or traumatic insult), become activated, produce proinflamma

221 in the intensive care unit with stable, non-traumatic intracerebral haemorrhage volume less than 30

222 diologically confirmed single spontaneous or traumatic intracranial hemorrhage, of whom 39 (83%) had

223 usal radiologically confirmed spontaneous or traumatic intracranial hemorrhage, of whom none had hear

224 ce and investigated how this influenced post-traumatic intraneural inflammation and neuropathic pain

225 embolization was successful in patients with traumatic leak and PLPS and, thus, should be considered

226 Patients with traumatic leak and PLPS were combined into 1 group of 16

227 ologies of chylothorax: 2 patients (8%) with traumatic leak from a thoracic duct (TD) branch, 14 pati

228 perimental housing conditions did not induce traumatic levels of chronic stress.

229 Traumatic life experiences are associated with alcohol u

230 stress with fear conditioning to precipitate traumatic-like memories.

231 target for treating disorders that stem from traumatic memories, yet little is known about how this p

232 ments (EMs) while simultaneously recalling a traumatic memory, which renders the memory less vivid an

233 f anesthesia, hypothermia, cardioplegia, and traumatic myocardial injury.

234 maging may provide early markers of onset of traumatic neurodegenerative disease.

235 ese cells attenuated the development of post-traumatic OA, reduced pain and increased cartilage devel

236 Traumatic optic neuropathy (TON) is a devastating cause

237 Traumatic optic neuropathy (TON) is an acute injury of t

238 e spectrum of lesions characteristic of post-traumatic osteoarthritis (PTOA) across the knee joint in

239 tients were evaluated for basketball-related traumatic retinal detachment.

240 ractalkine receptor, promotes recovery after traumatic spinal contusion injury in mice, a benefit ach

241 Traumatic spinal cord injury (SCI) causes a cascade of d

242 chemokine receptor, promotes recovery after traumatic spinal cord injury in mice, a benefit achieved

243 ontributes to pathological changes following traumatic spinal cord or traumatic brain injury (TBI).

244 omote resilience to adverse effects of acute traumatic stress and facilitate adaptation to repeated s

245 ty Disorder [GAD]-2 anxiety scale), and post-traumatic stress disorder (measured by the Post-Traumati

246 ontrol subjects (n = 20), patients with post-traumatic stress disorder (n = 25) demonstrated intrinsi

247 Part of the symptomatology of post-traumatic stress disorder (PTSD) are alterations in arou

248 KEY POINTS: Patients with post-traumatic stress disorder (PTSD) are at a significantly

249 in to elucidate the mechanisms by which post-traumatic stress disorder (PTSD) at a young age contribu

250 men are at increased risk of developing post-traumatic stress disorder (PTSD) following a traumatic e

251 ABSTRACT: Post-traumatic stress disorder (PTSD) is associated with incr

252 Post-traumatic stress disorder (PTSD) is characterized by exa

253 ctors, and correlates of cancer-related post-traumatic stress disorder (PTSD) symptoms and diagnoses.

254 We assessed patients' mood, post-traumatic stress disorder (PTSD) symptoms, and QOL 6 mon

255 Post-traumatic stress disorder (PTSD) was measured with the P

256 essive disorder (MDD), 50 patients with post-traumatic stress disorder (PTSD), and 122 healthy contro

257 s whether post-deployment screening for post-traumatic stress disorder (PTSD), depression, anxiety, o

258 g the effect of traumatic experience on post-traumatic stress disorder (PTSD), this study aims to exp

259 genetic response to traumatic stress on post-traumatic stress disorder (PTSD), this study examined lo

260 or type 2 (CRFR2) to be associated with post-traumatic stress disorder (PTSD)-like symptoms.

261 type is consistent with some aspects of post-traumatic stress disorder (PTSD).

262 ctional neurological disorder (FND) and post-traumatic stress disorder (PTSD).

263 ss-related psychopathologies, including post-traumatic stress disorder (PTSD).

264 reat is one of the defining features of post-traumatic stress disorder (PTSD).

265 highlight a unique sensory pathology of post-traumatic stress disorder (ruling out effects merely ref

266 ed symptoms of depression, anxiety, and post-traumatic stress disorder 1 year after flooding.

267 , for anxiety 1.66 (1.12-2.46), and for post-traumatic stress disorder 1.70 (1.17-2.48) than people w

268 s disorder (PTSD) was measured with the Post-traumatic Stress Disorder 8 items (PTSD-8) and severe me

269 rventions that might offset the risk of post-traumatic stress disorder after cardiovascular disease e

270 Interestingly, patients with post-traumatic stress disorder also showed heightened frontal

271 Post-traumatic stress disorder and anxiety are more prevalent

272 ndidate mechanisms for the link between post-traumatic stress disorder and cardiovascular disease, an

273 of symptoms of depression, anxiety, and post-traumatic stress disorder between participants displaced

274 umatic stress disorder (measured by the Post-Traumatic Stress Disorder Checklist [PCL]-6 scale).

275 carried mild traumatic brain injury and post-traumatic stress disorder diagnoses.

276 We conclude that post-traumatic stress disorder is a risk factor for incident

277 tive control, fuelling and perpetuating post-traumatic stress disorder symptoms.

278 four studies, more women presented with post-traumatic stress disorder than did men in two studies, a

279 tions help construct a vicious cycle in post-traumatic stress disorder that is in action even at rest

280 Scores for depression and post-traumatic stress disorder were higher in people who were

281 ding (p=0.04 for depression, p=0.01 for post-traumatic stress disorder), although the difference in a

282 examined the apolipoprotein E4 allele, post-traumatic stress disorder, and genetic risk for schizoph

283 ictims reported a greater prevalence of post-traumatic stress disorder, anxiety, or depression than d

284 understanding mental disorders, such as post-traumatic stress disorder, little is known about the sou

285 energic system, a known risk factor for post-traumatic stress disorder, modulates the stress-induced

286 To elucidate a sensory pathology of post-traumatic stress disorder, we examined intrinsic visual

287 disorders, such as chronic anxiety and post-traumatic stress disorder.

288 threat-neutral sensory hyperactivity in post-traumatic stress disorder.

289 its levels are reduced in patients with post-traumatic stress disorder.

290 n additional aetiological mechanism for post-traumatic stress disorder.

291 ine the impact of the epigenetic response to traumatic stress on post-traumatic stress disorder (PTSD

292 Life history events, such as traumatic stress, illness, or starvation, can influence

293 ed by existing evidence-based approaches for traumatic stress.

294 h Administration (VA) have a history of post-traumatic-stress-disorder (PTSD), and there exists a hig

295 Patients with post-traumatic-stress-disorder reported higher pain scores, h

296 Our data suggests that a history of post-traumatic-stress-disorder was correlated with higher pai

297 Secondary outcomes included history of post-traumatic-stress-disorder, anesthesia type, first or sec

298 The aggregate traumatic subarachnoid hemorrhage (tSAH) component of th

299 e that CN2097 significantly reduces the post-traumatic synthesis of proinflammatory mediators and inh

300 ean number of attempts, and the incidence of traumatic tap and backache did not differ significantly