ライフサイエンスコーパス: suppression

1 human immunodeficiency virus type 1 (HIV-1) suppression.

2 tive fields going far beyond simple surround suppression.

3 thway that is integral to p53-mediated tumor suppression.

4 NK pathway was involved in TAK1-mediated HBV suppression.

5 nt superpowers, to volcanically induced Nile suppression.

6 ore, this spider may play a key role in pest suppression.

7 he PALB2-BRCA1 interaction for breast cancer suppression.

8 90% of individuals on ART have durable viral suppression.

9 tes to predict long-term durability of viral suppression.

10 the Esx-1 function was restored by nonsense suppression.

11 -cognate aminoacyl-tRNA selection during PTC suppression.

12 ance Th2 cells and limit T reg cell-mediated suppression.

13 CCR2 does not directly participate in immune suppression.

14 miRNAs were up-regulated at later stages for suppression.

15 and prevented neurogenesis-induced synaptic suppression.

16 or burden, were not affected by beta-catenin suppression.

17 onal T cell responses and poor Treg-mediated suppression.

18 mmary luminal cell differentiation and tumor suppression.

19 pecies became more important for the invader suppression.

20 r, which is thought to be critical for tumor suppression.

21 patients with comitant strabismus and visual suppression.

22 red direction enhancement and null direction suppression.

23 and pathological conditions, including tumor suppression [2], embryonic development [3, 4], tissue re

24 isms to explain the association between fire suppression activity and acute myocardial infarction in

25 xhibiting the most profound case of pubertal suppression among mammals to explore a role for RFamide-

26 Rates of HIV viral suppression and adherence to ART were similar in the two

27 te viral disease associated both with immune suppression and development of life-long immunity.

28 ' has been linked to livestock grazing, fire-suppression and elevated atmospheric CO2 concentrations

29 ility of the goggles in patients with visual suppression and in children.

30 e necroptotic pathway in tumor promotion and suppression and in metastasis.

31 eceptor 2 (TNFR2) is known to mediate immune suppression and tissue regeneration.

32 reveal a new mechanism for TREX1-mediated L1 suppression and uncover a new function for TREX1 in prot

33 epresses transcription, restores SG assembly suppression and viral yield.

34 marate was non-inferior in maintaining viral suppression and was well tolerated at 48 weeks.

35 uding in differentiation, mitogenesis, tumor suppression, and neuronal plasticity.

36 alient target were associated with beta-band suppression, and target reappearances with beta-band enh

37 escues lipogenic defects associated with OGT suppression, and tumor growth in vitro and in vivo.

38 tion conditions by means of continuous flash suppression, and we tested in 24 healthy human participa

39 a strong correlation between the respiratory suppression/antinociception therapeutic window in a seri

40 e associated valley-protected backscattering suppression around the curved waveguide are further demo

41 We propose TE suppression as a mechanism for immune escape in AML and

42 r results show that, by allowing odor-evoked suppression as well as excitation, the responsiveness of

43 al load measurement after release) and viral suppression at LTC.

44 trap 3-amino tyrosine (NH2Y) by amber codon suppression at positions Y731 or Y730 and investigation

45 taneously, and a mechanism where prioritized suppression between the movements determines their seque

46 ner phoneme resulted in electrophysiological suppression, but only if the content of the inner phonem

47 arily by attenuation of Treg-mediated immune suppression, but the translatability to human GITR biolo

48 Erythroferrone mediates hepcidin suppression by anemia, but its mechanism of action remai

49 in Stat1-deficient mice, with no additional suppression by antibiotics in these mice.

50 sensory encounters, resulting in enhanced MC suppression by Arc-expressing IGCs.

51 2 is a major target of p53-independent tumor suppression by ARF and also suggest that the ARF-NRF2 in

52 -associated chromatin and abrogates hepcidin suppression by erythropoietin, iron deficiency, thalasse

53 complete phospho-Rb inhibition and cyclin D1 suppression by LY3009120 and abemaciclib combination led

54 teract with the FRU network to mediate sleep suppression by male sex drive.

55 rmore, SNAI2 transduction rescues metastasis suppression by miR-452.

56 Suppression by the mps mutation is specific to Deltalsr2

57 1 cells and displayed reduced sensitivity to suppression by Tregs relative to Th17 effectors from 13R

58 s of HIV-1 infection, respectively, and that suppression corresponds to defects in the accumulation o

59 ctivation in the brain with concurrent Abeta suppression could enhance plaque clearance and could imp

60 inhibitor of SERT, also resulted in Cyp19a1 suppression, decreased circulating 17beta-estradiol leve

61 elitis (an MS animal model), and the disease suppression depended on forkhead-box-protein-P3(foxp3)(+

62 Suppression depends on RelA-directed synthesis of (p)ppG

63 f the variation in postictal generalized EEG suppression duration (P < 0.02).

64 NOB suppression during intermittent aeration was mostly expl

65 on in firefighters are increased during fire suppression duties, and are likely to reflect a combinat

66 locations just ahead of the prior path, with suppression elsewhere in the surround.

67 ntified 53 national care continua with viral suppression estimates representing 19.7 million (54%) of

68 erations consistent with both activation and suppression evident within 1 hour of injury.

69 Chromatin analysis and shRNA-mediated gene suppression experiments indicated a similar function of

70 he hypothesis that the proportion with viral suppression for each long-acting regimen is not worse th

71 ing evidence base supports the use of immune suppression for the treatment of skin and lung fibrosis.

72 ex, especially in more severe amblyopes, but suppression from both the FE and AEs was prevalent in al

73 inical candidates for reactivating the tumor suppression function of p53 in cancer by dual targeting

74 strate the utility of the directional phonon suppression function, enabling new avenues for systemati

75 nterventions can improve adherence and viral suppression; generally, their estimated effects were mod

76 All participants maintained virological suppression (HIV-1 RNA <50 copies per mL) at week 24.

77 or of cytopathicity and host transcriptional suppression.IMPORTANCE Viruses must suppress host antivi

78 neurons are silenced, the normal male sleep suppression in female presence is attenuated and mating

79 servative DSB repair may contribute to tumor suppression in human cells.

80 Encapsulation causes 35-55% suppression in kappa and approximately 40% enhancement i

81 is the primary mechanism for IL-10-mediated suppression in LPS-stimulated macrophages and that inhib

82 Finally, stathmin suppression in neuroblastoma cells significantly reduced

83 ed the role of RFRP-3 in social reproductive suppression in NMRs.

84 arietal control network exhibited repetition suppression in response to "identical in-group" (Democra

85 The results suggest recent recombination suppression in S. latifolia, since its split from S. dio

86 he survival study, CR elicited a significant suppression in spontaneous mammary tumorigenesis.

87 TRAIL-R suppression in tumor cells impaired CCL2 production and

88 ent provides an opportunity to reduce immune suppression in tumor host.

89 king antibody CTX014 on MDSC-mediated T-cell suppression in tumor-bearing mice.

90 -Jagged1/2 to reprogram MDSC-mediated T-cell suppression in tumors, with implications to broadly impr

91 iking is linked to a high level of binocular suppression in visual cortex during development.

92 significant tremor relief (up to 87% tremor suppression) in selected patients with essential tremor

93 The cross-orientation suppression increases the sparseness of responses to nat

94 that targeting MUC1-C associated with PD-L1 suppression, increases in tumor-infiltrating CD8(+) T ce

95 se the tumorigenic phenotype induced by PTPA suppression, indicating they function as null alleles.

96 ask during three hormone conditions: ovarian suppression induced by the gonadotropin-releasing hormon

97 Symptom suppression is achieved by delivering stimulation to the

98 sults indicate that emergency, on-shift fire suppression is associated with significantly elevated ex

99 Side mode suppression is electrically modulated from 6 dB to 21

100 This suppression is involuntary, and cannot be avoided even i

101 PTC suppression is mediated by the base pairing of a near-co

102 Erk suppression is relieved through independent mutagenesis

103 tive effect of aPC, demonstrating that Nlrp3 suppression is required for aPC-mediated protection from

104 Results show that extraclassical suppression is significantly stronger for LGN neurons th

105 ears, weighed 25 kg or more, had virological suppression (<50 copies of HIV-1 RNA per mL) on a stable

106 th higher CD4 cell count and viral load (VL) suppression<400 c/mL among patients on antiretroviral th

107 Here we suggest that perceptual suppression may arise from efficient sensorimotor comput

108 This asymmetric suppression may be a key component of the perceptual los

109 fire activity due to climate change and fire suppression may have profound effects on the balance bet

110 , during developmental progression and tumor suppression, non-coding transcription orchestrates chrom

111 Acid suppression, nonsteroidal antiinflammatory drugs (NSAIDs

112 e, 0-4] for placebo; P < .01), with complete suppression observed in 11 of 13 patients (85%).

113 ronal excitability, with both excitation and suppression observed in significant proportions.

114 Viral suppression occurred in 3427 (81.6%) of 4202 HIV-positiv

115 SV-mediated antagonizing STAT3 could lead to suppression of a broad spectrum of cytokines and growth

116 nd that immunoproteasomes were important for suppression of a caspase-independent cell death and the

117 These observations were consistent with suppression of a muscarinic-sensitive K(+)-current, or M

118 ization interface was a prerequisite for the suppression of AAI and airway hyperresponsiveness by GCs

119 umans and atrophy of CA3 pyramidal cells and suppression of adult neurogenesis in rodents.

120 fter forced abstinence or punishment-induced suppression of aggression self-administration.

121 early months, with reduced proliferation and suppression of AKT, S6, ERK, and STAT3 activation.

122 Coupled with suppression of aldosterone secretion, activation of NCC

123 Light activation of beta-cells triggered a suppression of alpha-cell activity via gap junction-depe

124 We further demonstrate, that the suppression of alpha-syn aggregation is dependent on the

125 Ex vivo imaging showed that suppression of Amigo2 in luciferase-expressing LV12 cell

126 serotonergic neurons activation was due to a suppression of an inhibitory NPVF-ventral raphe peptider

127 paradoxical deprivation effect: interocular suppression of an ordinarily visible stimulus being view

128 olar solvent provided improved yield through suppression of an oxidative side reaction, while employm

129 or its role in a pathophysiological context: suppression of anti-tumor immunity.

130 l for the prevention of autoimmunity and the suppression of anti-tumor immunity.

131 o downregulation of the chemokine CXCL14 and suppression of antitumor immune responses.

132 s study defines a new role for EBNA3A in the suppression of apoptosis with implications for EBV lymph

133 sumption of a high-fat diet (HFD) results in suppression of ATP citrate-lyase levels in tissues such

134 e changes were linked with TAT-Gap19-induced suppression of ATP signaling and activation of the ERK1/

135 eptual learning.SIGNIFICANCE STATEMENT While suppression of auditory responses to self-generated soun

136 Impaired suppression of auditory stimuli was associated with core

137 Suppression of autophagy via hypoxia-induced expression

138 igh-glucose diet was given, seemingly due to suppression of autophagy.

139 SC-T cell interactions needed for sufficient suppression of autoreactive T cells and helps to underst

140 tgrowth, confirming the role of M1R in tonic suppression of axonal plasticity.

141 mor keratinocytes themselves, contributes to suppression of BCC carcinogenesis.

142 ination of large misoriented grains, and the suppression of big second phase particles in this 3.2 m

143 a subset of enhancers by inducing coordinate suppression of binding by MAF, lineage-determining trans

144 per year), and, in a subset of 553 patients, suppression of bone turnover (assessed by C-terminal tel

145 chanistic explanation for exercise-dependent suppression of breast cancer cell growth.

146 ppaB activation but was mediated through the suppression of c-Fos/AP-1 activity at transcriptional an

147 We propose that chronic suppression of calbindin by DeltaFosB is one mechanism t

148 ts ability to inhibit ROS production and the suppression of catabolic markers including IL-6, COX-2,

149 This Nrf1-mediated mechanism involves the suppression of CD36-driven inflammatory signaling and de

150 enotypes, including sustained proliferation, suppression of cell death, and altered metabolism.

151 Thus, active suppression of cell-mediated immune responses under immu

152 and serine (SER) all resulted in remarkable suppression of CF formation with only approximately 10%

153 T116 and DLD1 colon carcinoma cells leads to suppression of CHK1 and CHK2 activation in response to i

154 release of autoantigen was important for the suppression of clinical disease symptoms.

155 ells, which are directly responsible for the suppression of CNS-damaging autoreactive T cells.

156 e colon, where it has been implicated in the suppression of colitis and colon cancer.

157 CE STATEMENT Saccades are known to produce a suppression of contrast sensitivity at saccadic onset an

158 man neutrophil migration was associated with suppression of CXCL8/IL-8-mediated Ras-related C3 botuli

159 g inhibition of type I interferon responses, suppression of dendritic cell maturation and promotion o

160 entify specific mechanisms through which the suppression of DG affects memory performance.

161 tions in plasma total cholesterol levels and suppression of diet-induced weight gain.

162 However, suppression of disorder-induced scattering has never bee

163 Pif1 helicase: promotion of replication and suppression of DNA damage at tDNAs.

164 n some cellular contexts, dE2F/dDP-dependent suppression of DNA damage signaling is key for cell-cycl

165 2,3,7,8-tetrachlorodibenzo-p-dioxin-elicited suppression of early B and pro-B cells, suggesting a rol

166 Bs, which are normalized on RNaseH1-mediated suppression of ectopic R-loops, inversely correlates wit

167 l of plasma FFAs in these mice prevented the suppression of EGP during a clamp, reaffirming that the

168 insulinemia by enhancing insulin-stimulated suppression of endogenous glucose production.

169 Suppression of Erdr1 depends on detection of circulating

170 e coactivation-function of Stat3 resulted in suppression of expression of pluripotency factors.

171 Suppression of EZH2 protein expression induced chemoresi

172 ression partly rescues the defects caused by suppression of FGF signalling.

173 Importantly, suppression of GABAergic transmission via D2 receptor-gl

174 primordial germ cells (PGCs), as well as the suppression of germ cell tumours in mice.

175 abolomic and transcriptomic profiling marked suppression of glucocorticoid biosynthesis in the epider

176 Suppression of GnT-III in EOC cell lines and primary tum

177 ing MITF-dependent inhibition of invasion to suppression of guanylate metabolism.

178 s and inhibits HNF1alpha, thus relieving the suppression of hepatic PPARgamma expression and promotin

179 We conclude that suppression of hepcidin expression involves epigenetic r

180 Antiretroviral therapy (ART) that enables suppression of HIV replication has been successfully rol

181 Despite the efficient suppression of HIV-1 replication that can be achieved wi

182 ome-wide analyses implicate condensin in the suppression of hundreds of loci, acting in both DNA meth

183 In a macaque model of inhalation TB, suppression of IDO activity reduced bacterial burden, pa

184 agonists formoterol and salbutamol mediated suppression of IL-27p28 production, when triggered by zy

185 N in utero lacked constitutive CB1R-mediated suppression of inhibition from residual CCK-INTs and dis

186 suggest a novel mechanism for TREX1-mediated suppression of innate immune activation through maintain

187 sm for the severity of EBOV infection is its suppression of innate immune responses.

188 disorders in male offspring, resulting from suppression of intratesticular testosterone, and is used

189 Thus, this work indicates that suppression of JNK1/2 activity by MKP-1 maintains PARP-1

190 plete blockade of PFC-induced heterosynaptic suppression of less salient HP inputs.

191 .4-6.1; p<0.0001]) compared with virological suppression of less than 50 copies per mL.

192 f miR-125b, leading to Rybp upregulation and suppression of lineage-specific genes via RYBP-dependent

193 , Perry and colleagues provide evidence that suppression of lipolysis is a key facet of leptin-mediat

194 was significantly reduced and the resulting suppression of long term potentiation (LTP) by Abeta oli

195 on is initiated, and this is associated with suppression of LPS-induced enhancer activation.

196 thway of direct TGF-beta-dependent Treg-cell suppression of mast cell activation, in the absence of m

197 oxytocin signaling in the CeL prevented the suppression of maternal freezing.

198 nhanced viral burden in multiple organs, and suppression of MCMV-specific T cell memory inflation.

199 , our data suggest that, although short-term suppression of Mek1/2 in ES cells helps to maintain an I

200 applications to tissue regeneration and the suppression of metastasis.

201 tions of inorganic N to soils broadly show a suppression of microbial activity, which is inconsistent

202 migration, invasion, and glycolysis through suppression of microRNA (miR)-455-3p.

203 geting of IGF-1 and PI3K(p85alpha), and that suppression of miR-29b may represent a therapeutic appro

204 essing eIF4A, and functionally important for suppression of mTORC2 activity and invasion.

205 ) have not been previously associated to the suppression of mutations.

206 This is accompanied by suppression of MYC signaling and an increase in the T ce

207 RNA interference suppression of NaSIPP in Nicotiana spp. pollen grains di

208 Suppression of NFS1 cooperates with inhibition of cystei

209 Mammary or subcutaneous tumours grow despite suppression of NFS1, whereas metastatic or primary lung

210 Moreover, the suppression of NORE1A protein levels correlated almost p

211 duces cytoplasmic translocation of FoxO1 and suppression of Notch signalling.

212 Cancers display elevated O-GlcNAcylation and suppression of O-GlcNAcylation inhibits cancer invasion

213 ith a myelin antigen, led to myelin-specific suppression of ongoing experimental allergic encephalomy

214 citation at one selected resonance mode with suppression of other modes.

215 Suppression of parasite-specific peripheral blood mononu

216 Here, we show that suppression of PAX7 target genes is a hallmark of FSHD,

217 Similarly, we observed that inhibitory suppression of phasic noise generated by out-of-field ex

218 sion of gene expression; (2) indirectly, via suppression of pigment; and (3) Fe/S cluster biosynthesi

219 RT at less than ten months of age and showed suppression of plasma viremia for seven to nine years.

220 the hypothesis that this is mediated by the suppression of prediction error processing through the p

221 ial follicles than control ExECs, indicating suppression of premature mobilization that has been note

222 c inflammation (less cardiac infiltrates and suppression of proinflammatory cytokines), cardiac fibro

223 ells, ex-Th17 cells were highly resistant to suppression of proliferation and cytokines by regulatory

224 Transgenic overexpression and suppression of PtabZIP1L also resulted in modulation of

225 on with inhibition of IGF1R phosphorylation, suppression of Rac1 signaling, and activation of RhoA si

226 nt vascular pruning, but were accompanied by suppression of regulatory T cells and greater influx of

227 ost-ischaemic tPA treatment led to sustained suppression of regulatory T cells in the blood.

228 Conversely, acute suppression of RNF145 via shRNA-mediated knockdown, or c

229 Suppression of rRNA synthesis during IGF-1 treatment did

230 rther diminishes Bcl-2 expression leading to suppression of sAML cell growth, and enhancement of DNR

231 -responsive SMC gene promoters, resulting in suppression of SMC marker gene transcription and, conseq

232 Suppression of SOCS-4 influenced the responsiveness of H

233 Suppression of Sp7(Osterix) and Igf1 in bone, and serum

234 This includes a suppression of specific local circuits that supports, ra

235 lts explained by our model include the total suppression of stochastic pinning at single notches in t

236 hereby contributing to growth inhibition and suppression of stress-induced apoptosis.

237 such as increased cognitive control and the suppression of task irrelevant inputs.

238 tent with two distinct neural processes with suppression of task-irrelevant information occurring bef

239 however, their function is required for the suppression of tau toxicity by bas-1.

240 ify an endosiRNA-based mechanism involved in suppression of TE transcription.

241 s reservoirs for relapse, showed significant suppression of TEs and interferon pathways.

242 dysplastic syndrome (MDS) showed far greater suppression of TEs than low-risk cases.

243 s of pDCs with Treg cells, thereby enhancing suppression of Th1 anti-tumour immunity.

244 -35; IL-10 and TGF-beta together drove their suppression of TH2 cell proliferation.

245 Suppression of TH2 immunity can occur as a consequence o

246 In-phase optogenetic suppression of thalamic spindles impaired hippocampus-de

247 cell's preferred orientation or direction by suppression of the firing rate.

248 Suppression of the host phagosomal transport systems and

249 We recover the suppression of the Knight shift and the linear-in-T spin

250 mation begins at 14 GPa and is attributed to suppression of the local magnetic moments, destabilizing

251 ever, it has been recently reported that the suppression of the metal to insulator transition induced

252 the Rb checkpoint protein, but more thorough suppression of the transcriptional and cell cycle defect

253 Once fate decision is executed, the suppression of transcription of ribosomal genes and upre

254 he resulting data clearly indicated a potent suppression of tumor necrosis factor alpha release.

255 and that inhibition of this axis results in suppression of tumour growth in a transgenic mouse model

256 sical monocytes in conjunction with a global suppression of type I interferon-signalling pathway and

257 n-1 was dependent on UNC5A receptor, because suppression of UNC5A significantly inhibited NF-kappaB p

258 suppressor protein, p53, and apoptosis with suppression of urokinase-type plasminogen activator (uPA

259 HIRA is, however, required for suppression of viral gene expression, virus replication

260 Rapamycin treatment resulted in suppression of virus-specific B cell responses by inhibi

261 in heart muscle induced by systemic chemical suppression of Wnt signaling.

262 or-3 (M3R)-dependent manner, in part through suppression of yes-associated protein (YAP) function.

263 co-infected persons despite prolonged viral suppression often experience persistent immune activatio

264 onset epileptic encephalopathies with burst suppression (Ohtahara syndrome and early myoclonic encep

265 of TRPC6 and TRPC1 resulted in a comparable suppression on Ca(2+) entry with double knockdown of bot

266 N2A This idea was confirmed by RNAi-mediated suppression or genetic deletion of ETS1, which blocked C

267 eeks and 48 weeks without compromising viral suppression or increasing toxic effects.

268 Biological control offers sustainable pest suppression, partly because evolution of resistance to p

269 ntrol, prevention of genotoxic stress, tumor suppression, pathogen elimination, regulation of immunit

270 namic cellular calcium homeostasis and TXNIP suppression present viable pharmacologic targets to prev

271 easures such as bone water concentration and suppression ratio.

272 primary criteria for comparability in viral suppression relative to the oral comparator group.

273 p53-inducible genes most critical for tumor suppression remain elusive.

274 s, although the molecular mechanisms of this suppression remain incompletely understood.

275 Genome maintenance and cancer suppression require homologous recombination (HR) DNA re

276 ould be the identification of proteins whose suppression rescues F508del-CFTR function in bronchial e

277 rovide uniform surface coverage and dendrite suppression, respectively, thereby enabling the stable o

278 90-90-90 target for "on ART" and for "viral suppression," respectively.

279 siRNA-mediated spl suppression resulted in effects opposite to those observ

280 NIPA suppression results in a modest reduction of proliferati

281 NOTCH1 suppression results in changes in expression of genes in

282 tain an ICM-like epigenetic state, prolonged suppression results in irreversible changes that comprom

283 he initiation of the saccade with the visual suppression.SIGNIFICANCE STATEMENT Saccades are known to

284 ious LRP and LR development, while PtabZIP1L suppression significantly delayed both LRP and LR format

285 stronger fronto-hippocampal coupling during suppression, suggesting that interneurons local to the h

286 s a molecular target of Foxp3+ Treg-mediated suppression that leads to amelioration of autoimmune res

287 One clear case is saccadic suppression, the reduced visibility around the time of s

288 ts (e.g., triptorelin) are used for androgen suppression therapy.

289 e findings suggest that ZAP exploits host CG suppression to identify non-self RNA.

290 Thus, absence of VDR-mediated PPARgamma suppression underlies alopecia in VDR(-/-) mice.

291 classes and retention in care (RiC) or viral suppression (VS).

292 That translational suppression was more pronounced in terminal effector cel

293 compromise between susceptibility to loss of suppression when exposed to TAC and maintenance of a TSD

294 To unravel mechanisms of p53-mediated tumor suppression, which have remained elusive, we analyzed pa

295 showed full human immunodeficiency virus RNA suppression while receiving a TDF- or tenofovir alafenam

296 rebound in people that have achieved initial suppression with ART, to determine factors associated wi

297 Moreover, TF suppression with neutralizing antibodies blocked 15(S)-H

298 ltiparous brain exhibited features of immune suppression, with dampened baseline microglial activity.

299 ila melanogaster causes numerical population suppression, with the magnitude of effect positively cor

300 However, TGFbeta neutralizes SMAD4-mediated suppression without affecting SMAD4 binding to the Rorc