ライフサイエンスコーパス: short

1 n ultra-high density array (10,000/cm(2)) of short ( 230 mum) microprojections that delivers dry coat

2 ribution of CaMKII mRNA, which consists of a short 3'-untranslated region (UTR) form lacking regulato

3 plasmatic villin 1 decreased already after a short (3 hours) treatment with necrostatin-1 during rena

4 ng and ischaemia of a long (12-24 months) or short (3-6 months) treatment in relation to baseline ble

5 Our results show that the short 310-helix from D580 to S584 is critical for proper

6 Cost-saving short (50-bp) single-end reads and Nextera (R) library p

7 in-targeting drugs suggest that PMS contains short actin filaments that are depolymerization resistan

8 oximately 300 to approximately 900 nm, using short aminonitriles (dicyandiamide or cyanamide) as shap

9 uding Rous Sarcoma Virus (RSV), CA carries a short and hydrophobic spacer peptide (SP) at its C-termi

10 ents as CS and US, while alternating between short and long interstimulus intervals.

11 feasible but surgical outcomes and impact on short and long-term morbidity rates are yet to be determ

12 We discuss causes and functions of short and long-term patterns of specialization for bumbl

13 on and their relation with HRQoL in both the short and longer term.

14 and 0.49-0.63 (83.8% CI: 0.42, 0.68) for the short and standard MR imaging protocols.

15 Short- and long-run low gray-level emphasis and surface

16 ce in the presence of obesity have potential short- and long-term clinical implications.

17 be intelligently restructured to ensure that short- and long-term clinical outcomes continue to impro

18 efibrillator therapy is associated with both short- and long-term complications.

19 Vector-induced short- and long-term Mef2c upregulation in mouse prefron

20 al screening, is associated with substantial short- and long-term mortality.

21 lycolysis in human sarcomas was evaluated by short- and long-term rapamycin treatment in sarcoma cell

22 e an understanding of the interactions, both short- and long-term, between CS and SS firing.

23 Short- and medium-wavelength UV light can cause photo-le

24 Short arginine-rich proteins called protamines mediate t

25 Stable laser pulses with a duration as short as 660 fs are readily obtained at a repetition rat

26 d chemical nature of the tunneling medium at short biological tunneling distances.

27 r parenteral support volume in patients with short bowel syndrome (SBS) with intestinal failure, incr

28 M344 displays short brain exposure, indicating that brief pulses of da

29 t rhythmicity among MS neurons and fire with short burst duration (median, 38 ms) preferentially at t

30 of a continuous subthreshold sine wave with short bursts of suprathreshold pulse-trains inserted at

31 Existing studies have investigated short- but not long-term risk.

32 ompared with terahertz sources fabricated on short-carrier-lifetime substrates.

33 during normal aging of a cell, followed by a short catastrophe phase in which noise increased.

34 Fermentation end products, in particular the short-chain fatty acid (SCFA) acetate, are believed to b

35 when cultured with butyric acid, a principal short-chain fatty acid in the fermentation metabolites o

36 naerobic metabolism, like butyrate and other short-chain fatty acids (SCFAs), induce regulatory T cel

37 Short-chain fatty acids (SCFAs), such as butyrate, produ

38 Levels of the fecal short-chain fatty acids acetate and caproate were reduce

39 ceramides, and an increased incorporation of short-chain fatty acids and dihydroxylated bases into in

40 disaccharides partially restored total fecal short-chain fatty acids from the level significantly rep

41 osis and more severe NASH, based on a set of short-chain TAGs and FFAs.

42 The incorporation of short channels can be adopted in the designs of dosage f

43 the range between 450 and 800 nm, and a high short-circuit current density (J SC ) of 17.92 mA cm(-2)

44 show higher values in open-circuit voltage, short-circuit current density, fill factor, and thereby

45 to compete with the excitonic interactions, short-circuiting the I --> II --> III sequence.

46 jection in mouse was characterized by a very short circulation time ( 0.44h), lower area under the cu

47 ly-used formulation) have been studied using short-column sedimentation equilibrium in the analytical

48 necklace' dislocation consisting of multiple short component dislocations in adjacent twins, connecte

49 und directly to a gold current collector via short conducting linkages eliminates the need for filler

50 success of antiviral therapy combined with a short course (in hospital only) HBIG in liver transplant

51 atory study provides limited evidence that a short course of IVIG administered in the MCI stage of AD

52 nge 2.2-5.6) per 100 000 population with the short-course regimen and 4.3 (2.9-7.6) per 100 000 popul

53 with continued use of longer therapy-ie, the short-course regimen could reduce incidence by 23% (10-3

54 s later flowering than the wild allele under short day and exhibits a signature of selection.

55 lained 59% of flowering time variation under short days.

56 s with overly elongated hypocotyls mainly in short days.

57 After a short delay, these clusters abruptly disperse and oscill

58 ors associated with the primary outcome were short disease duration (odds ratio [OR] 0.64, 95% CI 0.4

59 richosis, microphthalmia, short stature, and short distal phalanges.

60 r pollution concentrations vary sharply over short distances (<<1 km) owing to unevenly distributed e

61 iers in West Antarctica need to retreat only short distances before they reach extensive retrograde s

62 ys work when applied to species separated by short divergence times or that contain introgressed gene

63 ganic dye, the dissociation kinetics of very short DNA and conformational changes of biomolecules wit

64 e GSIS, selective reduction of exocytosis of short-dock (but not no-dock) newcomer SGs accounted for

65 Long and short doublets were the dominant songs in Southern Calif

66 , we study the effect of spermine binding to short duplex RNA and DNA, and compare our findings with

67 Short duration, intense pulses of light can experience d

68 plete tumour responses are infrequent and of short duration, possibly because of the short half-lives

69 e enzymes display weak activities for only a short duration, these efficient nanofactories protect hu

70 e to an increase in nursing home episodes of short duration.

71 This short encounter was sufficient to significantly inhibit

72 characteristics (theoretical response slope, short equilibration time, excellent potential stability,

73 electron-phonon interaction, resulting in a short exciton lifetime in the MoS2 /GaN heterostructure.

74 Our brief review provides a short explanation of these emerging MRI methods and outl

75 Short exposure of HCV-infected cells to daclatasvir redu

76 esults indicate that subsurface behaviour in short-finned pilot whales is more complex than a simple

77 mptoms, sinonasal outcome test (SNOT)-22 and Short Form (SF)-36 questionnaires.

78 range of outcomes, including three of eight Short Form 36 (SF36) domains (d=0.46-0.79).

79 ctional status, and quality of life (12-Item Short Form Health Survey, ranging from 0 to 100, with hi

80 IND-VFQ), and Medical Outcomes Study 36-item Short Form Survey (SF-36) were obtained at enrollment an

81 hological outcomes, quality of life (36-Item Short Form Survey and 20-item Multidimensional Fatigue I

82 Pain was estimated using the 36-Item Short Form Survey.

83 son with dementia and general health status (Short Form-12 health survey [SF-12]) for the caregiver.

84 or-prone repair, leading to substitution and short frameshift mutations, they are both a source of ge

85 t, ectopic Cyclin E overproduction uncouples short G1 from fast MCM loading.

86 infrared rebrightening in the afterglow of a short gamma-ray burst at redshift z = 0.356, although fi

87 l loop, preferentially binds to and fills-in short gapped DNA intermediates with RNA and LigC ligates

88 As a proof-of-concept, we delivered short guide RNAs targeting 3 genes critical for cardiac

89 a, located in its mid-dorsal part (posterior short gyrus).

90 Male domestic short hair cats (n = 20), underwent either sham procedur

91 chymal delivery of an adeno-associated virus-short hairpin RNA construct was sufficient to markedly a

92 rest, and that reducing DHX33 levels through short hairpin RNA interference has the same effect.

93 ponse of B-ALL to GCs with a next-generation short hairpin RNA screen to identify GC-regulated "effec

94 ably transduced PC12 cells with an inducible short hairpin RNA targeting clathrin heavy chain, result

95 nses to IL-17 using a tetracycline inducible short hairpin RNA targeting TRAF3IP2.

96 xpression of GPA, GPB, or GPC via lentiviral short hairpin RNA transduction of erythroid progenitor c

97 e gene expression consequences of expressing short hairpin RNAs (shRNAs).

98 d of short duration, possibly because of the short half-lives and suboptimal bone marrow exposure of

99 r cell (tall HCs) at the expense of another (short HCs) that is usually located furthest from the Wnt

100 Free-electron lasers providing ultra-short high-brightness pulses of X-ray radiation have gre

101 tor from the Rgg family and its cognate SHP (short hydrophobic peptide).

102 bservations: Subclinical AF is asymptomatic, short in duration, and usually detected with long-term,

103 ardiovascular and fibrotic diseases, but its short in vivo half-life is an obstacle to long-term admi

104 tively small numbers of large eggs with very short incubation periods (average 11-85 d).

105 integration for pursuit is consistent with a short integration MT subpopulation.

106 ted a presymptomatic reduction or absence of short interval intracortical inhibition, accompanied by

107 han being dominant-negative regulators, Tcf1 short isoforms are adequate in supporting developing thy

108 These data reveal that Tcf1 long and short isoforms have distinct, yet complementary, functio

109 efficient counteraction of both the long and short isoforms of this restriction factor.

110 in mice, while retaining expression of Tcf1 short isoforms.

111 In short, laminin alpha2 in the BM seems to play a crucial

112 actory sensory neuron (OSN) stimulation with short latencies regardless of stimulation intensity, MC

113 keep track of the target, on top of inducing short latency disturbance of grip force, single-pulse TM

114 ing operation remains challenging due to the short length scales involved and the reactive environmen

115 ontained long longitudinal actin cables, the short Li1 fiber cells accumulated disoriented transverse

116 some limitations including poor performance, short-lifetimes, and expensive ion-selective membranes a

117 The short-limbed dwarfism metaphyseal chondrodysplasia type

118 A short-linear interaction motif between residues 337-343

119 n the glomerular capillaries, where they are short lived and make a modest contribution to glomerular

120 ent study, we have discovered that PDK4 is a short lived protein (t(1/2) approximately 1 h) and is sp

121 al studies indicate that these exceptionally short-lived and low-abundance species form Watson-Crick-

122 This short-lived burst in kinase activity links development w

123 the gene encoding FOXO1, T cells revert to a short-lived effector phenotype, exhibit reduced viabilit

124 Mn(2+) upconversion emission and relatively short-lived lanthanide upconversion emission in a partic

125 phenomena arise from a confluence of rapid, short-lived positive signals driven by the protein tyros

126 eport on LSD in 1950, psychedelics enjoyed a short-lived relationship with psychology and psychiatry.

127 lived response) and immunoglobulin G3 (IgG3; short-lived response indicating more recent infection) f

128 The p53 tumour suppressor protein is a short-lived transcription factor that can inhibit the gr

129 ncer chest wall metastases but responses are short-lived.

130 ides evidence of an association between very short (<6 months) or very long (>18 months) wait times a

131 The short measure was comparable to the comprehensive measur

132 in situ analysis of DNA microviscosity with short measurement times (8 s) using small volumes (<3 mu

133 as it allows for very low amounts of sample, short measurement times and equilibrium binding conditio

134 mes an unusual conformation that allows this short motif to be bound directly by both CPSF-30 and WDR

135 and visualization of position-specific ultra-short motifs from a set of aligned sequences.

136 tools typically miss these position-specific short motifs, we developed kpLogo, a probability-based l

137 s found in the diagnostic performance of the short MR imaging protocol consisting of only transverse

138 -linker will produce disordered transport of short MTs and increased mobility of longer MTs.

139 ng an explanation for the frequent pauses of short MTs and the immobility of longer MTs.

140 observed for a mixture of Abeta1-28WT and a short N-terminal fragment, Abeta1-6A2V, which supports a

141 tension around Na and effectively soften the short Na-O bond along the polar axis - an effect that is

142 o disulfide bridges named tau-AnmTX Ms 9a-1 (short name Ms 9a-1) according to a structure similar to

143 ssing and imprinting processes, but at ultra-short (nanosecond) timescales.

144 Expansions of short nucleotide repeats produce several neurological an

145 s far required invasive measurements or fall short of being subject specific due to a lack of the nec

146 by decades of limited resources, has fallen short of fully enforcing its mandates.

147 These short oligomers convert to more closely packed membrane

148 undergoes proteolytic cleavage resulting in short OPA1 (S-OPA1).

149 ing allograft acceptance without significant short- or long-term toxicity.

150 ia and are associated with rapid relapse and short overall survival.

151 y, we used a clustered regularly interspaced short palindromic repeat (CRISPR)-Cas9 technology, gene-

152 (GenERA), a clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 platform for in

153 promoter via clustered regularly interspaced short palindromic repeats (CRISPR)-enzymatically inactiv

154 The CRISPR (clustered regularly interspaced short palindromic repeats) system protects archaea and b

155 opment using Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-associated gene9 (CRISP

156 Using rationally designed short peptide sequences, we determined that the charge t

157 nize a diverse array of targets, including a short peptide.

158 e high frequency of these residues generates short peptides, some of which are too small or uninforma

159 After a short period of soaking in a KBr solution, stable and re

160 mporal resolution over ca. 2.5 cycles of the short-period respiratory oscillation.

161 ate to the protease through recognition of a short phenylalanine-rich motif, and the presence of simi

162 This temporal uncoupling became larger in short photoperiods and may reflect the differing depende

163 We grew Arabidopsis plants in very short photoperiods and used a combination of extended ni

164 Our model suggests that cool temperatures or short photoperiods can induce cessation in autumn.

165 The low hemolysis of 2.39% with short prothrombin time (PT) and activated partial thromb

166 ognition strictly requires the presence of a short protospacer adjacent motif (PAM) flanking the targ

167 eted illumination, outcomes were similar for short pulses (1/10 ms long: 0% success) but improved for

168 show that the interruption of long nights by short pulses of light ("night-break" [NB]) accelerates w

169 Short QT syndrome (SQTS) is a rare condition characteriz

170 rare condition characterized by abnormally 'short' QT intervals on the ECG and increased susceptibil

171 y eye disease was defined from the validated Short Questionnaire for Dry Eye Syndrome (SQDES) as a pr

172 Short ragweed (Ambrosia artemisiifolia) allergies affect

173 on energy transfer is typically limited to a short range ( 1 mum), and additional losses may be incur

174 zation; however, Fat2/Lar signaling mediates short-range communication between neighboring cells inst

175 re for all densities, with the importance of short-range impurity scattering resulting in a "universa

176 domains, as switching markedly favors local (short-range) contacts over distant ones.

177 tion patterns, readily available substrates, short reaction time, transition metal-free, and gram-sca

178 diol products (up to 97% isolated yield), in short reaction times under mild experimental conditions

179 relative to standard batch conditions, with short reaction times, increased safety profile, and pote

180 ced by using a less coordinating solvent and short reaction times.

181 t position-specific nucleotide biases in HTS short read data.

182 cy and functional annotation data as well as short read support for the called variant.

183 three-way comparison including the published short-read assembly (SR) constructed for the same indivi

184 erited SVs reveals novel variants, missed in short-read data sets, a large proportion of which are re

185 ) and fragile X syndrome, is challenging for short-read whole-genome sequencing (WGS) data.

186 ad sequencing can overcome the weaknesses of short reads in the assembly of eukaryotic genomes; howev

187 From approximately 1.92 billion short reads, the largest number of differentially expres

188 ides a count of RNA molecules in the form of short reads, yielding discrete, often highly non-normall

189 In this short review, we particularly discuss the importance of

190 >10 s), when stalled complexes release their short RNA and make another without escaping.

191 Using chemically synthesized short RNA corresponding to the first 19 nucleotides (nt)

192 question of how many reads need to support a short RNA molecule in a given dataset before it can be c

193 n unmet need in rapid, reliable detection of short RNA regions which could open up new opportunities

194 ingly, the population prevalence for genetic short root anomaly (SRA) with no apparent defects in cro

195 Critically, diminished sensory processing at short RSIs, indexed by the stimulus-evoked P1 component,

196 f absolute need, uncertain daily demand, and short shelf life, platelet products are frequently waste

197 propose that viruses that are vulnerable to short-sighted evolution may exhibit strategies that mini

198 equence of this greater increase in pCa50 at short SL was that pCa50 did not increase any further at

199 leep, and early awakenings), sleep duration (short sleep 5 hours or less; long sleep greater than 8 h

200 rsal structures on their seeds compared with short species.

201 The second derived feature is the very short spinal cord, which terminates midway along the tho

202 y and facial hypertrichosis, microphthalmia, short stature, and short distal phalanges.

203 the NPR2 guanylyl cyclase both cause severe short stature, but how these two signaling systems inter

204 ormone receptor deficiency (GHRD) results in short stature, enhanced insulin sensitivity, and low cir

205 ies have only been designed and deployed for short-stature crops.

206 nhibitor cystine knot domains separated by a short, structurally well-defined linker.

207 alk that sampled exhaustively from images in short, successive cycles (i.e., that increasingly minimi

208 ing proteins and a variety of complexes with short synthetic peptides.

209 Short tandem repeats (STRs) are hyper-mutable sequences

210 Identifying large expansions of short tandem repeats (STRs), such as those that cause am

211 ouble-Blind, Placebo Controlled Study of the Short Term Clinical Effects of Tolvaptan in Patients Hos

212 ew scientific problems can be tackled in the short term, and what long-term directions are envisioned

213 y of prolonged (continuous or >/=3 h) versus short-term (</=60 min) infusion of antipseudomonal beta-

214 ive as buprenorphine-naloxone in maintaining short-term abstinence from heroin and other illicit subs

215 nables biological systems to make continuous short-term adjustments for optimal functioning despite e

216 were examined in a prospective registry for short-term and 30-day outcomes.

217 ), a common pregnancy complication which has short-term and long-term adverse health ramifications fo

218 ry (AKI) in children is associated with poor short-term and long-term health outcomes; however, the f

219 In recent years, short-term antiviral therapy for pregnant women in the t

220 altered the actin structure in long-term and short-term assays.

221 h certainty evidence), cognition measured by short-term attention (-0.23 points on a 100 point scale,

222 Response to warming in the short-term can be either positive or negative, but long

223 ental concentrations of mercury, are driving short-term declines in THg concentrations in southern Be

224 ehavior disorder (IRBD) patients at risk for short-term development of clinically defined synucleinop

225 Furthermore, short-term dynamics are also predicted, with simulation

226 We examine the short-term effects of the largest-scale policy shift, Ca

227 ) maintenance program after PR preserves the short-term effects on outcomes in patients with COPD.

228 ased stress reduction may be associated with short-term effects on pain intensity and physical functi

229 associated with small to moderate, primarily short-term effects on pain.

230 utated in cancers can often have substantial short-term effects, but the emergence of resistant cance

231 ial to evaluate the feasibility, safety, and short-term efficacy of bariatric embolization, a recentl

232 Short-term exposure of cultured rat hippocampal neurons

233 We show that short-term exposure to various forms of PE, displaying d

234 To estimate the association between short-term exposures to ambient fine particulate matter

235 Thus, under short-term Fe(III)-reducing conditions facilitating the

236 he loading concentration had no influence on short-term fluorescein release and pre-coating of beads

237 rds Panthera pardus exhibit a unique form of short-term food caching, regularly hoisting, storing and

238 nd recipient risk factors than NKAS kidneys, short-term graft and patient outcomes are acceptable.

239 odulation of BK channels in vivo can enhance short-term habituation.

240 vary microbiome; however, we also found that short-term hospitalization does not impact the richness

241 unknown how the oral microbiome responds to short-term hospitalization.

242 may be less susceptible to dysbiosis during short-term hospitalization.

243 Short-term IL-33 treatment in mice led to sustained expa

244 entify the effectiveness of prolonged versus short-term infusion of antipseudomonal beta-lactams in p

245 Short-term mechanical circulatory support, natriuretic p

246 ylcholine from prefrontal cortex can disrupt short-term memory performance and is reminiscent of Alzh

247 valuated using intraoperative complications, short-term morbidity, long-term morbidity, short-term mo

248 There is still a high rate of short-term mortality and complications in acute coronary

249 , short-term morbidity, long-term morbidity, short-term mortality, and long-term mortality.

250 centers had improved perioperative outcomes, short-term mortality, and overall survival.

251 te decompensation, organ failure(s) and high short-term mortality.

252 minant calcium sensor required for classical short-term neutrophil responses.

253 factors such as benzodiazepine exposure and short-term outcomes.

254 ociated with mortality (P = 0.24) during the short-term period (1,606 patient-months at risk), but th

255 lly contributes to both the excitability and short-term plasticity alterations that we observed.

256 Thus, basal synaptic strength, short-term plasticity, and homeostasis are determined in

257 a stimulus train and does not contribute to short-term plasticity, but induces a steady-state, async

258 dies (bNAbs) may be a viable alternative for short-term prophylaxis or treatment.

259 lsive therapy may be associated with reduced short-term psychiatric inpatient readmissions among psyc

260 Short-term psychoanalytical therapy was as effective as

261 ing of beads with body fluids did not affect short-term release or antibacterial activity.

262 These findings support the short-term renal safety of TDF/FTC PrEP in HIV-seronegat

263 ethosuximide, lamotrigine, and valproate had short-term seizure outcome determined.

264 pression levels in mouse skin are induced by short-term solar UV irradiation, and a long-term skin ca

265 for intravenous infusions and restriction to short-term studies (hours) in controlled laboratory sett

266 INTERPRETATION: In this short-term study, risankizumab was more effective than p

267 s hampered by numerous challenges, including short-term surveillance that focuses on single epidemics

268 rangements in both neuronal excitability and short-term synaptic plasticity-parameters that criticall

269 After short-term treatment at week 12, the placebo-adjusted ge

270 Indeed, short-term treatment with growth hormone augmented senes

271 i.e., day versus night) better-explained the short-term variability in water quality parameters and b

272 perature modelling suggest limited impact of short-term warming on gas hydrates deeper than a few met

273 The secondary end points included short-term weight loss, serum obesity-related hormone le

274 Adding exercise to a short-term weight-loss program should be considered as a

275 cies-level, suggesting infection-associated, short-term, within-host selection pressures.

276 ture media upon exposure to high temperature short time (HTST) treatment, a commonly used viral clear

277 cal association with cell surfaces over very short time periods under convective current.

278 o small geographic areas, are conducted over short time periods, and employ a wide range of survey pr

279 nctional composition changes over relatively short time scales in European forests.

280 work, we study nuclear shape fluctuations at short time scales of seconds in human cells.

281 modulate cross-modal temporal influences in short time scales.

282 n) enables the analysis to be performed in a short time, achieving high selectivity and sensitivity l

283 port regime is altered from "linear" at very short time, where the amperometric responses of the supp

284 g on atmospheric pCO2 levels on geologically short timescales (10(3)-10(5) years) remains poorly cons

285 reconfiguration and executive functions over short timescales and provide a candidate entry point tow

286 ucture even if the fibers themselves are too short to be resolved with TEM.

287 iation, and that isoprenoid stepping ensures short transit times.

288 stance with institutional volume established short travel/low-volume (ST/LV) and long travel/high-vol

289 thin minutes of exposure to CLCA1 or after a short treatment with nocodazole, consistent with the hyp

290 songs in Southern California, while long and short triplets were dominant in the Gulf of California.

291 nts have a synthetic phenotype consisting of short, twisted roots with disordered cortical microtubul

292 the surface of 293T cells (293T/S-alphaPEG, short-type cells; 293T/L-alphaPEG, long-type cells; 293T

293 g Lolium perenne peptides (LPP) and having a short up-dosing phase has been developed to treat grass

294 etrieved and then retrieved after a week, 24 short videos.

295 Undergoing surgery in a hospital with short vs long postoperative hospitalization practices, c

296 was further seen when inhibitory effects of short wavelength light were reduced with increasing seru

297 andscape evolution model to demonstrate that short-wavelength deformation causes drainage directions

298 wavelength (L)-, middle-wavelength (M)-, and short-wavelength sensitive (S)-opsins, are responsible f

299 than in EU and EA, and under experimentally short winter conditions NA species required 84% more spr

300 For example, hypomethylated genes tend to be short yet encode significantly more transcripts than exp