ライフサイエンスコーパス: resolution

1 low-temperature 120 K sc-XRD study at 0.90 A resolution.

2 quantify protein copy number with nanoscale resolution.

3 cal density of states with nanometre spatial resolution.

4 ical systems with better than 10 mum lateral resolution.

5 hich require a much lower pressure detection resolution.

6 atus), have been determined at 2.2 and 2.4 A resolution.

7 evel can be optically modulated with similar resolution.

8 tch in drug-resistant bacteria with temporal resolution.

9 e in response to a known force with cellular resolution.

10 s viscoelastic data with high spatiotemporal resolution.

11 d into accordingly brighter images at <30-nm resolution.

12 ng fibroblasts during fibrosis formation and resolution.

13 iction for human intergenic miRNAs at a high resolution.

14 y is relatively insensitive to data temporal resolution.

15 es in a dense cytoplasm with single-molecule resolution.

16 roBlo t 1 (rproBlo t 1), determined at 2.1 A resolution.

17 coat assembled on membranes in vitro at 9 A resolution.

18 of the molecular structure with submolecular resolution.

19 document seven major SV classes at 5 kb SV resolution.

20 robiome signatures at a meaningful taxonomic resolution.

21 arance, cardiomyocyte proliferation and scar resolution.

22 when analyzed at 1.6 x 1.6 x 1.6 mm(3) voxel resolution.

23 interface remain poorly understood at atomic resolution.

24 identification of CGRs with single base pair resolution.

25 e specifications in terms of sensitivity and resolution.

26 mechanisms governing fibrosis formation and resolution.

27 ned the crystal structure of m4-1BB to 2.2-A resolution.

28 e receiving placebo to have complete symptom resolution.

29 r defining protein stability at single amide resolution.

30 tions that often limit penetration depth and resolution.

31 t complexity requires studies at single-cell resolution.

32 the entire image at homogeneous high spatial resolution.

33 mosome structure with unprecedented temporal resolution.

34 tibody from a human survivor at 3.2-angstrom resolution.

35 ndary metabolites with large effects at high resolution.

36 pared to a classical acquisition at the same resolution.

37 unction at unparalleled spatial and temporal resolutions.

38 y ecologists focus on small extents and fine resolutions.

39 Here we present a high-resolution (100 m x 100 m) regional (10,000 km(2)) CH4 f

40 olution, five images per second; and spatial resolution, 150-mm field of view, and 128 x 128 matrix)

41 ) and 20 healthy volunteers underwent a high-resolution [(18)F]FEPPA PET scan and MRI.

42 actile apparatus Ca(2+) ion responses (force resolution 1microN, 0-10mN for the given sensor; [Ca(2+)

43 s during control pacing and reveals the high-resolution 3-D spatial structure of calcium gradients an

44 A high resolution (3 km foot print) SM/ST dataset prepared from

45 tion microscopy (SIM), we have captured high-resolution 3D images showing MOF uptake by HeLa cells ov

46 g and fusing macrosection images yields high resolution 3D maps of multiple tumor microenvironment co

47 Iterative REconstruction (GENFIRE), for high-resolution 3D reconstruction from a limited number of 2D

48 By applying ultra-high-resolution 7 T fMRI, we delineated the functional contri

49 Here, we use a newly developed, high-resolution (800 mum isotropic), quantitative MRI techniq

50 Using liquid chromatography coupled to high-resolution accurate mass tandem mass spectrometry, the r

51 oxygen dynamics at a high, quasi-continuous resolution across both scales.

52 ense visual information with varying spatial resolution across the visual field (foveated vision) and

53 observations of Bornean orangutans with high-resolution airborne remote sensing (Light Detection and

54 elivery enables thermometry with single-cell resolution, allowing neurons to be activated by exceptio

55 s here followed in vivo in real time at high resolution along several hundred micrometers of the zebr

56 )H MRS approach at 3 Tesla with high spatial resolution and absolute quantification, GPC+PC levels fr

57 bution of proteins on the genome with higher resolution and accuracy than existing approaches.

58 ressing these issues by increasing screening resolution and analyzing the effects of off targets on h

59 considerations of their use in both kinetic resolution and asymmetric synthesis.

60 ative precipitation variability and the high resolution and dating accuracy of this record allow us t

61 oli cells, with approximately 300 nm spatial resolution and high chemical sensitivity.

62 spectrometry (nano-DESI/HRMS), and ultrahigh resolution and mass accuracy 21T Fourier transform ion c

63 and, in time, will provide higher taxonomic resolution and more precise estimation of abundance.

64 FET-negative, most likely because of scanner resolution and partial-volume effects.

65 junctions in a complex behavior at cellular resolution and provide a tool for similar exploration of

66 rom presentation to documentation of symptom resolution and recurrence within 3 months.

67 conditions as they can provide high temporal resolution and require no sample preparation.

68 lex with human HGPRT was determined at 2.0 A resolution and shows that it fills three key pockets in

69 -scale peak volumes and achieved the highest resolution and signal-to-noise performance of any MALS m

70 elength range from 700 to 2500nm, at 2cm(-1) resolution and using a 0.2mm path length CaF2 sealed cel

71 Our approach offers unprecedented temporal resolution and, uniquely, physical transformations of li

72 re of Aqy1 at room temperature (RT) at 1.3 A resolution, and by exploring the structural dynamics of

73 picomolar sensitivity with high hydrodynamic resolution, and can be carried out with photoswitchable

74 iation dosage to the patient, higher spatial resolution, and shorter volumes to be interpreted.

75 PNPEP3 with bound apstatin product at 1.65 A resolution, and we compare its in vitro substrate specif

76 The coarse resolution AOGCMs outputs were statistically downscaled

77 uel cell (SOFC) operations with 5-mm spatial resolution at 800 degrees C.

78 e records single-spin NMR spectra with 13 Hz resolution at room temperature.Dissipation of the sensor

79 o characterizing samples with subdiffraction resolution at the nanoscale.

80 r-resolution fluorescence imaging and higher-resolution atomic structure determination, to cover the

81 ant detection limits and high (3 s) temporal resolution, attributes suggesting that the approach coul

82 In this study, we infer high resolution brain connectivity matrices using diffusion i

83 ack the community diversity at high temporal resolution by calculating phenotypic diversity estimates

84 nges in nuclear morphometrics at single-cell resolution by combining fluorescence imaging and deep le

85 ld colloids can be quantified with molecular resolution by differential centrifugal sedimentation (DC

86 modified isothermal EXPAR combined with high-resolution capillary electrophoresis-based single-strand

87 High resolution ChIP-exo was used to analyze in vivo the asso

88 nt quality of PALM imaging, and that spatial resolutions comparable to dSTORM can be achieved with CR

89 with lacrimal sac abscess results in faster resolution compared with secondary treatment.

90 b-diffraction limited imaging with a spatial resolution consistent with the gap size.

91 Here, we report high resolution cryo electron microscopy (cryo-EM) maps of wi

92 ral studies, through which we present a high-resolution cryo-electron microscopy (cryo-EM) structure

93 Comparison with a 7.8 A resolution cryo-electron microscopy map of a Mediator-RN

94 Here we present high-resolution cryo-electron microscopy structures of subtyp

95 proximately 250-550, we report here the 2.3A resolution crystal structure of a complex containing Sac

96 Here, we report the 2.25 A resolution crystal structure of the GAPDH1 holoenzyme in

97 basis for this stabilization with an atomic resolution crystal structure.

98 High-resolution crystal structures of CARM1 in complex with t

99 High-resolution crystal structures of reconstructed homodimer

100 Herein, we present two additional high-resolution crystal structures of the same RNA duplex con

101 High-resolution crystallographic structures provide invaluabl

102 ith purposefully designed ligands using high-resolution crystallography and isothermal titration calo

103 The methodology involves a multivariate resolution curve fitting known as non-negative matrix fa

104 High-speed high-resolution data acquisition now permits rapid measuremen

105 ty of this system in the acquisition of high-resolution data sets of dynamic samples.

106 The crystal structure at 1.9 A resolution deciphered that S1P binds to the surface of 2

107 Here we analyze a new high-resolution deep-sea oxygen isotope (delta(18)O) record f

108 provements in detection sensitivity and size resolution during the past decades.

109 e that the promising capability of this high resolution elastography imaging system for characterizin

110 show that native mass spectrometry and high resolution electron microscopy can define the subunit to

111 ctive quantum efficiency and combined energy resolution/energy field-of-view are offered by counting

112 iving mice demonstrate single-neuron spatial resolution even when optically targeting randomly distri

113 ial biomechatronics systems that can address resolution, experimental versatility and mostly, automat

114 isceral arteries and the vena cava (temporal resolution, five images per second; and spatial resoluti

115 f ECT with other techniques, including lower-resolution fluorescence imaging and higher-resolution at

116 These high-resolution fMRI findings suggest that model-free aspects

117 gene "birth." TGA provided single-nucleotide resolution for each binding site and delineated a highly

118 s quantified by calculating the peak-to-peak resolution for each pairwise combination of amino acid i

119 athways and identify key issues that require resolution for full understanding of pathogenic autoimmu

120 nformation was obtained with <100 nm spatial resolution for phase separated particles with a approxim

121 t, we consider the complex topic of defining resolution for this imaging modality and address some of

122 reconstruction of real-life sounds from high-resolution functional magnetic resonance imaging (fMRI)

123 Here, we applied 7 T high-resolution functional magnetic resonance imaging (fMRI)

124 s regional regression model to provide finer resolution future climate projections as inputs to the d

125 High-resolution geophysical surveys and underwater SCUBA divi

126 fferent downscaled climate models and a high-resolution global climate model, and create a generalize

127 of whole biological organs with microscopic resolution has remained a challenge.

128 nation microscopy resulted in an increase in resolution, highlighting the advantages in using a small

129 High-resolution hindcast of hurricane-generated sea states an

130 nant diseases relies on antigen-level (lower resolution) HLA typing for HLA-A and HLA-B, and allele-l

131 for Central Asia, based on a continuous high-resolution ice-core Hg record from the Belukha glacier i

132 coupled mass spectrometry (ICP-MS) and high-resolution ICP-MS, respectively.

133 of ultrahigh sensitivity and SLIM SUPER high-resolution IM separations.

134 High-resolution images of the stilbene fluorescence provided

135 nts of the discrete cosine transform for low-resolution images.

136 Live-cell super-resolution imaging is rare, as it is generally assumed t

137 agents for both superlocalization and super-resolution imaging, offering benefits such as high photo

138 ugs and large proteins with nearly base-pair resolution in an unbiased fashion.

139 rocytosis and its possible links to impaired resolution in atherosclerosis are incompletely understoo

140 re, the concept of dysregulated inflammation resolution in atherosclerosis has been known for several

141 dults, the natural history and predictors of resolution in children are not known.

142 for in vivo measurements of oxygen with high resolution in the brain extracellular space.

143 etinoin therapy has achieved nearly complete resolution in the two probands in whom it has been appli

144 ed (R)-roscovitine can speed up inflammation resolution in vivo more efficiently than the free drug.

145 The resolution increases roughly as the inverse of the NUS r

146 High-temporal resolution information can provide more meaningful estim

147 to more peaks to interpret compared to lower resolution instruments.

148 ven their chirality, may even be amenable to resolution into optically pure enantiomers.

149 Stable, high-resolution intravital imaging of the lung has become pos

150 nduced water splitting with improved lateral resolution is achieved.

151 Inflammation resolution is an active process that functions to restor

152 origins of disease; however, cellular-scale resolution is not readily achievable in intact tissue vo

153 data reduction strategy for analysis of high-resolution LC-MS is also demonstrated.

154 es, and organic acids, was performed by high-resolution LC/MS techniques.

155 ser frequency combs can rapidly measure high-resolution linear absorption spectra.

156 Using high-resolution live imaging, we examined the spatiotemporal

157 roteins (pcFPs) are powerful tools for super-resolution localization microscopy and protein tagging.

158 This holds particularly true for super-resolution localization microscopy where high demands ar

159 5 vs. 0.36 logarithm of the minimum angle of resolution (logMAR), P < 0.001), greater mean BCVA impro

160 Mass resolution (M/DeltaM fwhm) is observed to linearly incre

161 26 healthy control (HC) subjects, with high-resolution magnetic resonance imaging (MRI) to estimate

162 ) maps is a major challenge, as the moderate resolution makes accurate placement of atoms difficult.

163 we provide the first genome-wide, base pair-resolution map of 6mA in Tetrahymena by applying single-

164 expression, and beta-galactosidase for high-resolution mapping of expression patterns post-mortem.

165 Single-nucleotide-resolution mapping of m(6)A coupled with ribosome profil

166 Hence, high resolution mapping of transcriptional repression reveals

167 on this climate event, only few include high-resolution marine records that span the YD.

168 lternatively, we have developed a novel high-resolution mass spectrometry (HRMS) based approach for a

169 injection-electrospray ionization-ultrahigh resolution mass spectrometry (uHRMS) and based on the ca

170 Yet, high-resolution mass spectrometry analyses reveal a huge chem

171 on reaction samples were analyzed using high-resolution mass spectrometry and electron-capture detect

172 We applied high-resolution mass spectrometry and mass-defect filtering t

173 Using various low- and high-resolution mass spectrometry instruments with several co

174 iation (OzID) in-line with LC, IMS, and high resolution mass spectrometry.

175 he measurements decreases; consequently, the resolution (mean/sigma) improves by a factor equal to th

176 High-resolution membrane protein structures are essential for

177 High-resolution micro-computed tomography (micro-CT) analyses

178 State-of-the-art pixels for high-resolution microdisplays utilize reflective surfaces on

179 High-resolution microscopic imaging confirms the formation of

180 mouse models of acute leukemia, we used high-resolution microscopy and flow cytometry to highlight th

181 Super-resolution microscopy offers a significant gain in resol

182 Single-molecule-based super-resolution microscopy offers researchers a unique opport

183 c and biochemical tools, development of high-resolution microscopy, and identification of centriole c

184 Despite progress in super-resolution microscopy, discriminating and quantifying th

185 red protein family as novel probes for super-resolution microscopy.

186 ral region of the nucleus, as shown by super-resolution microscopy.

187 ucture prediction techniques to predict high-resolution models.

188 The selectivities of high-resolution MS (HRMS) alone or in combination with all-io

189 tified by a combination of HPLC-PDA, LC-high resolution MS (LC-HRMS), LC-tandem MS (LC-MS/MS) and nuc

190 tags for quantitative proteomics using high-resolution MS acquisition on the Orbitrap Elite and Orbi

191 n that a single nozzle can print fibers with resolution much finer than the nozzle diameter by stretc

192 overcame these limitations by acquiring high-resolution multidimensional nonlinear coherent spectra w

193 By combining high-resolution multidimensional single- and double-quantum (

194 luding aerosol mass spectrometry (AMS), high-resolution nanospray desorption electrospray ionization

195 roteoform profile of C9 was acquired by high-resolution native mass spectrometry, which revealed the

196 an Orbitrap mass spectrometer, enabling high-resolution native MS analysis of 0.8- to 2.3-MDa prokary

197 uickly written and erased over 50 times with resolution nearly equivalent to that obtained with a com

198 s created from molecular and structural high-resolution neuroimaging data consisting of positron emis

199 During inflammation resolution, neutrophils undergo apoptosis before they ar

200 t displays features of impaired inflammation resolution, notably a necrotic core and thinning of a pr

201 d reflectance, fundus autofluorescence, high-resolution OCT, and ultrawide-field imaging.

202 The epimerization and chiral resolution of 27c followed by further synthetic manipula

203 calization is routinely limited to a peptide resolution of 5 to 20 amino acid residues.

204 al data.A number of parameters influence the resolution of a cryo-EM structure.

205 solving mediators that actively regulate the resolution of acute-inflammation, and correlate measurem

206 A new catalyst for the dynamic kinetic resolution of azole hemiaminals has been developed using

207 e did not result in higher rates of clinical resolution of cellulitis in the per-protocol analysis.

208 previously classified as having spontaneous resolution of chlamydia.

209 ides one way to identify where improving the resolution of climate data will have the largest impact

210 The unprecedented resolution of cold-ion spectroscopy coupled with tandem

211 BAT can also be used to monitor resolution of food allergy and the clinical response to

212 me annotation with a substantially increased resolution of gene models will not only further our unde

213 These data suggest H3-G34R slows resolution of HR-mediated repair and that unresolved rep

214 lectron microscopy structures at near-atomic resolution of Hsp104 in different translocation states.

215 mation transferred up to 2.1 A, allowing the resolution of individual atomic columns of Zn and organi

216 icant role in the clearance of infection and resolution of inflammation and contributes to mucosal ho

217 rs and pharmacologic agonists that stimulate resolution of inflammation and infection.

218 ings, H89 prevented ROL- and Bt2cAMP-induced resolution of inflammation, and it was associated with d

219 macrophage factors that are associated with resolution of inflammation, Dectin-1, CD206 (mannose rec

220 utes to subsequent clearance of Brucella and resolution of inflammation.

221 roles in regulating the timely promotion and resolution of inflammation.

222 that characterize AMD and showed accelerated resolution of inflammation.

223 thin 1 to 2 weeks of treatment, and clinical resolution of lesions within 2 months.

224 g advantage of the high spatial and temporal resolution of light control, optobiology promises to pro

225 sis of hepatic stellate cells to promote the resolution of liver fibrosis.

226 tudies offer a molecular explanation for the resolution of palatal defects, showing that Eda and Edar

227 a three-dimensional fibrin matrix and during resolution of peritoneal inflammation, whereas migration

228 In five of eight longitudinal cases, the resolution of SSPiM resulted in the formation of conflue

229 not increase the proportion of patients with resolution of symptoms at 24 hours.

230 that Fgfr2 regulates both the formation and resolution of tetrads and rosettes in the mouse embryo,

231 We took advantage of the improved size resolution of the 8-pore devices to analyze in real time

232 histone modifications, but the accuracy and resolution of these methods remain limited.

233 The resolution of this paradox required the insight that an

234 The temporal resolution of ultrafast electron diffraction and microsc

235 Early resolution of uncertainty during an epidemic outbreak ca

236 o diagnose an issue with TXS solubility, the resolution of which yielded a 25-fold improvement in tax

237 4 and antibody 17b, or with antibody b12, at resolutions of 3.7 A and 3.6 A, respectively.

238 Mass resolutions of 36900 (fundamental), 75850 (2nd harmonic)

239 tion microscopy offers a significant gain in resolution over traditional optical microscopy, enabling

240 gated with quantum state specificity by high-resolution photoelectron spectroscopy of the vinylidene

241 This dynamic kinetic resolution process offers a general approach to the synt

242 ture of FNO in complex with NADP(+) at 1.8 A resolution, providing the first bacterial FNO structure.

243 ylogenies and ancestral genomes for two high-resolution real yeast genome datasets.

244 A recent analysis of a high-resolution record reveals large orbitally driven variati

245 estions, as each variant differs markedly in resolution, reproducibility, throughput and biases.

246 d that the TAPI may be used to estimate 24 h resolution RM concentrations in Nevada.

247 superstructure phenomena revealed by atomic-resolution scanning TEM (STEM) and single-crystal diffra

248 in capillaries and microchannels offers high-resolution separations, such formats can be cumbersome t

249 The crystal structure at 2.19 A resolution shows a large displacement of the catalytic l

250 High-resolution single-molecule and single-cell analyses demo

251 Here we use high-resolution single-molecule microscopy to directly observ

252 re) surfaces of biochar particles using high-resolution spectro(micro)scopy and mass spectrometry.

253 These findings indicate that high-resolution structural information about the membrane-ins

254 cular dichroism measurements to provide high-resolution structural insight into the functional amyloi

255 No structural homologs or high-resolution structure exists for the TP domain.

256 Here we show the high-resolution structure of melon (Cucumis melo) eIF4E in co

257 tal scanning approach, we determine the high-resolution structure of the radiation sensitive molybden

258 of the IL-1alpha/aptamer, we provide a high-resolution structure of this critical cytokine and we re

259 r flexibility limits both the number of high-resolution structures available, leaving only a small nu

260 y to medicine was evident, as the first high-resolution structures emerged in the 50s and 60s.

261 ence-dependent features of DNA found in high-resolution structures introduce irregularities in the di

262 parent organisms, and opens the door to high-resolution systematic analyses of C. elegans morphogenes

263 was identified by liquid chromatography high resolution tandem mass spectrometry (LC-HRMS/MS).

264 al, in part due to a dearth of suitably high-resolution techniques to probe molecular architecture in

265 e accurately captured in our model at higher resolution than previous studies.

266 detection is a measure of auditory temporal resolution that relies on the auditory cortex (ACx), and

267 o succeed given its low temporal and spatial resolution, the neural code must be smooth at the voxel

268 line and amorphous limits) with high spatial resolution through selective helium ion irradiation with

269 sources, which can be studied with high time resolution, thus providing access to picosecond dynamics

270 n the atmosphere (measured by an online high-resolution time-of-flight mass spectrometer) and dissolv

271 ance imaging (MRI) does not offer sufficient resolution to discriminate the notochord from the surrou

272 processed by dissolution (for double HJ) or resolution to ensure genome stability.

273 le-cell RNA sequencing provides unparalleled resolution to study cellular heterogeneity.

274 to the lack of adequate optical microscopic resolution to study human synapses.

275 n during development, and they help to bring resolution to this long-standing debate.

276 behavioral experimentation, we show that the resolution to this tension-and the adaptation of social

277 Furthermore, we enhance spatial resolution (to <300 nm in all three dimensions) by apply

278 GEOS-Chem simulations (2x2.5 masculine grid resolution) to estimate annual O3 exposures, and estimat

279 d nano-composites were characterized by high resolution transmission electron microscopy (HRTEM), ene

280 ation of bulk analytical techniques and high resolution transmission electron microscopy.

281 Calcium imaging with cellular resolution typically requires an animal to be tethered u

282 Here we combine high-resolution underway O2/Ar, which provides an estimate of

283 to the antipsychotic drug nemonapride, with resolutions up to 1.95 angstroms.

284 or capsid protein, elucidated at near-atomic resolution using cryo-electron microscopy, is strikingly

285 mitting simultaneous acquisition of two high-resolution views otherwise difficult to obtain due to st

286 The mean (SD) time to symptom resolution was 13.8 (5.8) days in the intervention group

287 rce spectroscopy optimized for 1-microsecond resolution, we reexamined the unfolding of individual ba

288 These high-resolution, week-long, time series enabled simultaneous

289 e Japanese encephalitis virus at near-atomic resolution, which reveals an unusual "hole" on the surfa

290 s study patterns at large extents and coarse resolutions, while community ecologists focus on small e

291 d to inversion of configuration in a kinetic resolution with an extremely high selectivity factor (E

292 cryoEM structure of yeast U1 snRNP at 3.6 A resolution with atomic models for ten core proteins, nea

293 ned animals has combined high spatiotemporal resolution with large volume coverage.

294 s, assisting structure determination to high resolution with minimal data.A number of parameters infl

295 2006 to 2100 is very similar at high and low resolution, with the result that the number of years of

296 We report a 3.4-A resolution X-ray crystal structure of a sigma(N) fragmen

297 me model based on previously published 3.8-A resolution X-ray data.

298 ColN-T is invisible in the high-resolution x-ray model and yet accounts for 90 of the to

299 ignificant changes were detected in the high-resolution X-ray reflectivity data with monotonic increa

300 The high-resolution Y-SNP haplogroup and Y-STR haplotype can be o