ライフサイエンスコーパス: relevant

1 binding protein, and hemocyanin are the most relevant.

2 s-species lentiviral transmissions is highly relevant.

3 function during cold exposure is clinically relevant.

4 -locum tenens physicians were not clinically relevant.

5 ns might be more biologically and clinically relevant.

6 se, and hence their monitoring is clinically relevant.

7 nced by whether or not object shape was task-relevant.

8 n exposure to these compounds is thus highly relevant.

9 d numerous times but are not physiologically relevant.

10 [(13)C]-Glyc as a novel agent for clinically relevant (13)C MRS studies of energy metabolism and furt

11 A significant variety of biologically relevant AA side chains are tolerated including those fo

12 rning approaches based on genomics and other relevant accessible information for use in predicting ho

13 ty for potent binding across therapeutically relevant adenosine receptors (A1, A2a, and A3) as well a

14 between gait speed and PiB uptake withstood relevant adjustments; however, APOE epsilon4 rendered on

15 f RP in dogs, rcd1 and xlpra2, at clinically relevant advanced stages of the two diseases.

16 ve not yet been conducted, particularly in a relevant airway background using a functional readout.

17 vely activated macrophages do not synthesize relevant amounts of catecholamines, and hence, are not l

18 2%) class-waivered drugs were considered not relevant and 16 (18%) required further data.

19 ined phenotyping, to make sure the cells are relevant and comparable between labs, and outline why th

20 s early in multiple sclerosis, is clinically relevant, and may arise from one or more mechanisms that

21 specific times at which they are deemed most relevant; and (2) the neural substrates that support suc

22 otein Tetraspanin 1 (TSPAN1) as a clinically relevant androgen regulated target in prostate cancer.

23 ng inherited retinal degenerations; however, relevant animal models and biomarkers of progression in

24 markers of outcome measures, availability of relevant animal models, and robust functional rescue fro

25 resistance of the gonococcus to a clinically relevant antibiotic.

26 depletion upon exposure to three clinically relevant antimicrobials (colistin, imipenem or ciproflox

27 , here we demonstrate a more physiologically relevant approach to target discovery in glioblastoma.

28 Relevant articles were retrieved from Pubmed, EMBASE, an

29 This is clinically relevant, as overly softened and stiffened clots are ass

30 unique cell division cycle in the clinically relevant asexual blood stage of infection(1).

31 cytotoxicity of human-origin type 1 diabetes-relevant autoreactive CD8(+) T cells.

32 We defined five clinically relevant backbone groups on the basis of established pro

33 and environmental risk factors and it may be relevant background data in clinical genetic counseling.

34 , and remained significantly associated with relevant behaviours after controlling for the family str

35 ed maps might become clinically feasible and relevant, being simpler than currently available alterna

36 n DBS in mumol/L)/0.73, with a nonclinically relevant bias of -2.1 mumol/L (95% CI, -3.7 to -0.5 mumo

37 cts, one major challenge is to find the most relevant bioinformatics toolkits that will lead to new k

38 tures in water, an essential feature for any relevant biological application.

39 c diagnostics could help discover clinically relevant biomarker combinations pivotal for understandin

40 stance, and inform development of clinically relevant biomarkers and trials of combination therapies.

41 often overlooked when developing clinically relevant bispecific therapeutics.

42 There was a small non-clinically relevant but statistically significant (0.2 [SD 1.1] vs

43 ts into how the introduction of biologically relevant, but poorly understood, modifications to cytosi

44 are expected to lead to more physiologically relevant cardiac tissue-like in vitro models for mechani

45 A catalytically relevant catalyst-substrate adduct has been observed, an

46 Clinically relevant cataract surgical skills can be improved by pro

47 about the distributional properties of task-relevant categories, in addition to sensory information,

48 reclinical alcohol research aims to identify relevant CeA neuroadaptions that promote the transition

49 ed polygenic model that can prioritize trait-relevant cell types and genes from GWAS summary statisti

50 ls that mimic infection in a physiologically relevant, cellular context.

51 with excellent structural homology to other relevant channels sensitive to general anesthetics and,

52 ith this model, we can identify functionally relevant circuit motifs and generalize the framework to

53 molecular disease subtypes characterized by relevant clinical differences, such as survival.

54 This Series paper focuses on the most relevant clinical questions, summarises the results of r

55 omorbidity Index (HCT-CI) were recognized as relevant clinical variables for HSCT eligibility.

56 site features suggest distinct functionally-relevant clusters.

57 tion had pervasive impairments in clinically relevant cognitive functions, including general intellig

58 spA peptide mixed with other physiologically relevant components like bovine serum albumin (BSA) and

59 aracteristics and assays covering clinically relevant concentrations in physiological saline, we demo

60 ns in the presence and absence of clinically relevant concentrations of 3 commonly used antifungals:

61 ology of chronic exposure to environmentally relevant concentrations of these complex mixtures has no

62 induce S. rosetta mating at environmentally relevant concentrations, suggesting that bacteria likely

63 s shown here, to barbiturates, at clinically relevant concentrations.

64 f emerging concern (CECs) at environmentally relevant concentrations.

65 SH-Cu(I) complexes formed under biologically relevant conditions remain controversial.

66 in vitro than chrysin under physiologically relevant conditions such as in platelet-rich plasma and

67 ese experiments-performed under biologically relevant conditions-answer long-standing questions in me

68 traits in their offspring in a functionally relevant context using a fully factorial design.

69 and these sounds are used in communicatively relevant contexts.

70 iatal feedback, and occur with behaviourally relevant cortical input.

71 eviewed the evidence on whether primary care-relevant counseling interventions to promote a healthful

72 Methodological rigor was assessed using the relevant Critical Appraisal Skills Programme tools.

73 l reaction intermediates agree well with the relevant crystal structures, validating the computationa

74 ta sources.The study was designed to compare relevant data published by the Food and Agriculture Orga

75 precise molecular measurements at clinically relevant detection limits and high (3 s) temporal resolu

76 By allowing all the relevant diagnostic terms for anaphylaxis to be included

77 h the predefined hypothesis of no clinically relevant differences after induction between groups.

78 As such, functionally relevant differences in averaged power across time and t

79 mpler phases; aquatic baseline toxicity; and relevant diffusion coefficients.

80 erefore sought to determine how a clinically-relevant dose of cryotherapy would impact the transcript

81 n) or low ( 1:1000 dilution) physiologically relevant dose of simulated mixture in air for two weeks

82 ly sensitive to ibrutinib at therapeutically relevant drug concentrations.

83 nAMD was evident across multiple clinically relevant end points.

84 ements, immunoblotting or gene expression of relevant enzymes.

85 s, the hybrid molecule was designed to cover relevant epitopes and evaluated in silico.

86 s information of immortalized cell lines and relevant experimental components.

87 Clinically relevant Ezh2 inhibitors restore androgen receptor expre

88 eal biomechanics and represents a clinically relevant factor that needs further investigation.

89 ches, the inability to structurally annotate relevant features and map them to biochemical pathways i

90 n cut-off frequency omegamax as the two most relevant features, and new classes of models featuring f

91 These clinically relevant findings should have significant influence on f

92 ccine platform for ZIKV and other clinically relevant flaviviruses.

93 We examined purchases of health- and policy-relevant food and beverage groups [e.g., fruit and sugar

94 water conductive shear zone under conditions relevant for a nuclear waste repository in crystalline r

95 nistic, which makes systems with a large DMI relevant for applications.

96 features of real-world stimuli that are most relevant for behavior (i.e., speech, voice).

97 functionally coherent modules that might be relevant for cancer progression.

98 ncer, with particular emphasis on mechanisms relevant for cancer stem cell formation (CSC) and functi

99 this negativity: a finding which may also be relevant for clinical imaging of other hematological can

100 ts into mechanisms through which RCL1 may be relevant for depression.

101 greement that experimental data are directly relevant for determining grammar architecture, we presen

102 It may therefore be relevant for diagnostic purposes or therapeutic interven

103 pro-TGF-beta1 in an orientation biologically relevant for force-dependent release of TGF-beta from la

104 ions that would make the humanitarian system relevant for future public health responses: (1) operati

105 are valid for correctly decoding information relevant for grasping.

106 ntibody is an important biophysical property relevant for its developability into a therapeutic.

107 in chronic myelogenous leukemia (CML) may be relevant for long-term control or cure of CML.

108 We identify 49 genes relevant for mitotic rounding, a large portion of which

109 ncomplete knowledge about the TBK1 functions relevant for neurodegeneration.

110 This basic structural information could be relevant for providing light on the mechanisms involved

111 Metabolic control may be relevant for refining inclusion criteria of clinical tri

112 ing regions, temporal modulations in a range relevant for speech analysis ( approximately 2-4 Hz) wer

113 s place at an even lower pace, only becoming relevant for structures held in vacuum or under extreme

114 regime where elastic collisions also become relevant for suspensions of microscopic particles, behav

115 ment into larger spatial segments, which are relevant for task performance.

116 ION: These standardised outcome criteria are relevant for the assessment of the success of surgical t

117 thylation-based tumour classification highly relevant for the future diagnosis and treatment of menin

118 These findings are relevant for three reasons.

119 Our findings are relevant for understanding how sequence-encoded informat

120 These effects are relevant for understanding V. cholerae pathogenicity and

121 tic pathogens (protists & fungi), along with relevant free-living and non-pathogenic species, and sel

122 ro antioxidant capacity which appears highly relevant from an industrial perspective.

123 e A2A adenosine receptor, a pharmaceutically relevant G protein-coupled receptor.

124 fication and carbon capture demonstrated for relevant gas mixtures.

125 rase inhibitors preferentially target cancer-relevant genes and can be combined with inhibitors targe

126 her analysis, we focus on 12 therapeutically relevant genes and consider how genetic variation affect

127 e the ability of clinically and biologically relevant genes and gene signatures (GSs) measured by RNA

128 ations, we recommend prioritizing clinically relevant genes for functional studies, developing refere

129 ylation and altered expression of metabolism-relevant genes.

130 M344 increases the expression of AD-relevant genes: BDNF, alpha-secretase (ADAM10), MINT2, F

131 S likely depends on tDCS intensity, and task relevant genetic factors (e.g., for WM: COMT val(158)met

132 We analyzed relevant genomic data from all currently available seque

133 biotic susceptibility profiles of clinically relevant Gram-negative bacteria within two hours of anti

134 ng acoustic dimensions that are functionally-relevant-here, formant frequencies that are crucial for

135 ritical information from the physiologically relevant htt exon-1 (Httex1) protein has been challengin

136 in HVPG and BW were predefined as clinically relevant if >/=10% and >/=5%, respectively.

137 eening data collected for a pharmaceutically relevant IgG4 mAb being characterized to determine the e

138 uenza vaccination promotes the prevalence of relevant immune cells in tonsillar follicles and support

139 ing (or not) laboratory mice as a useful and relevant immunological model system.

140 Also, amyloid imaging results seem to have a relevant impact on caregivers.

141 ed with alterations in microbial communities relevant in blood pressure control.

142 Elevated levels of CRP are common and relevant in CSU patients.

143 channel subunits and ion channel modulators, relevant in human AF.

144 areas; these AIS increases were behaviorally relevant in the brain's fusiform face area.

145 irome on health and disease may be even more relevant in this population.

146 res the nature of urea-aromatic interactions relevant in urea-assisted protein denaturation.

147 ne-learning approaches were used to identify relevant in vivo, ex vivo, and patient features and thei

148 udy was to analyze the formation of the most relevant inflammation mediators including proteins and l

149 Attention involves the selection of the most relevant information for differential sensory processing

150 o perception, serving to select behaviorally relevant information for privileged processing.

151 e evaluate them for their ability to provide relevant information under preclinical and clinical circ

152 STAN, a material flow system comprising all relevant inputs, stocks and outputs of wastes, products,

153 yrosine kinases, including the highly cancer relevant insulin-like growth factor type 1 receptor (IGF

154 KKbeta-driven gene expression and clinically relevant invasion and metastasis gene signatures.

155 ytic activity but differ with respect to the relevant iron redox state.

156 al biomass can be induced using a clinically-relevant iso-osmotic agent.

157 eurons of the hippocampus after a clinically relevant isoflurane anesthesia exposure conducted at an

158 e vapor composition and NW composition using relevant kinetic parameters.

159 oth markers are detectable across clinically relevant levels by label free impedance derived redox ca

160 routine analysis of uric acid at clinically relevant levels in urine patient samples.

161 Health Literature were searched to identify relevant literature using the search terms, Practice Env

162 s in MDS and further prioritize biologically relevant lncRNAs using the NLCFA.

163 mental monitoring, which provide practically relevant LODs with high expandability and adaptability.

164 Thus, we have discovered a new biologically relevant, lumisterogenic pathway, the metabolites of whi

165 n the confounder in order to choose the most relevant measure for each patient.

166 However, H doping is a challenge to WO3, the relevant mechanisms being hardly understood.

167 c device will facilitate drug screening in a relevant microenvironment thanks to its simple, effectiv

168 fetal bovine serum (FBS), a physiologically relevant mixture of proteins, on Mg and Mg alloy degrada

169 g the transmitted virus, a more biologically relevant model.

170 rs, confirm that dogs deficient in HACD1 are relevant models, and strengthen the evidence for a unify

171 phrocyte can be used to elucidate clinically relevant molecular mechanisms underlying the pathogenesi

172 oduce an emerging field we term functionally-relevant morphological profiling with great potential to

173 Several natural product-relevant motifs are accessed in enantioenriched form for

174 dependent worsening of the AD phenotype in a relevant mouse model of the disease.

175 nced IL-13-induced gene expression in asthma-relevant murine and human cells.

176 inhibition in CKD developed in a clinically relevant murine model of nonischemic hypertrophic CHF, t

177 tion - and examine coherent activity between relevant networks of brain regions during exposure to he

178 istic gene expression data from biologically relevant networks that can be user selected.

179 Our study introduces a clinically-relevant neuroimaging ageing biomarker and demonstrates

180 Here we report a physiologically relevant NMDA-receptor-independent mechanism that drives

181 ly, we show why the described mechanisms are relevant not only in hypertension, but also in the case

182 se that presents high incidence and yields a relevant number of fatal cases (about 20,000) every year

183 In conclusion, we demonstrate a relevant number of patients with FDG-PET false-negative

184 ive strategy for expanding a therapeutically relevant number of stem cells.

185 Finding relevant objects through vision, or visual search, is a

186 involved in constraining the decision to the relevant options.

187 behavior, it is not clear which neurons are relevant or how they contribute.

188 995 and December 31, 2015 were included, and relevant outcome data were extracted from the Medical Bi

189 The definition, etiology, and clinically relevant outcomes associated with malnutrition are revie

190 However, 8-h policy-relevant ozone design values increase in all cases.

191 sulation, which is a single and biologically relevant parameter.

192 handling were assessed, together with other relevant parameters.

193 s that summarizes new and revised clinically relevant parasite taxonomy from January 2012 through Dec

194 -) cells similarly increased in number after relevant pathological insults (infarcts), suggesting a s

195 However, relevant pathomechanisms of nephrotic syndrome have not

196 nd potential replacement of pharmaceutically relevant PEGs by alternative macromolecules offering a s

197 and red tomato juices differ in biologically relevant phytochemicals beyond carotenoids.

198 re hampered by the lack of a physiologically relevant, preclinical model of allogeneic HSCT.

199 insulin resistance and could be a clinically relevant predictor of MS development.

200 ng an agreed taxonomy or factor structure of relevant processes.

201 strength and cross-reactivity to clinically relevant profilins.

202 C) retention times can be used to predict 26 relevant properties for nonpolar chemicals, specifically

203 vealed recurrent genomic alterations, with a relevant proportion affecting genes of the lysine demeth

204 site, yet the exact nature of catalytically relevant protein motions remains largely unknown.

205 , leading to a selective depletion of cancer-relevant proteins after turnover.

206 g the structure and function of biologically relevant proteins.

207 ibliographies were also reviewed to identify relevant publications.

208 pus (last updated November 2016) to identify relevant published studies reporting the performance of

209 However, a remaining clinically relevant question is whether early post-status epileptic

210 by genetic tractability, but by ecologically relevant questions and hypotheses.

211 xciting basic microbiological and clinically relevant questions.

212 The relevant R package miLineage is publicly available.

213 responsiveness of CRAF fusions to clinically relevant RAFi.

214 The functionally relevant random-coil-alpha-helix transition associated w

215 ubMed, EMBASE and the Cochrane databases for relevant RCTs and calculated pooled OR for 3-month morta

216 rtitioning between ancestral mammals and the relevant reptiles, our results suggested partial overlap

217 ew we will provide an overview of continuing relevant research and highlight different approaches tow

218 pe extraction is based on integration of the relevant retinal information over space.

219 ctive on appropriate medications, and assess relevant risk factors including renal disease, antiphosp

220 rches were prospectively defined to identify relevant safety end points, including arterial thromboem

221 Further, biologically relevant scaffolds, such as alpha-quaternary beta-homo p

222 R diffusion and distribution in biologically relevant scenarios ex vivo, in vitro and in vivo.

223 on to extensive annotation of several domain-relevant semantic classes, and connection to complete sy

224 work that the presence of a physiologically relevant shearing flow rate results in very different si

225 ds, generating an assortment of biologically relevant signaling mediators.

226 er to direct their attention toward the most relevant signals.

227 wastewater showed the presence of clinically relevant slow growers like M. kansasii, M. szulgai, M. g

228 is high speed imaging confirms a technically relevant solidification front velocity and cooling rate

229 ving this control directly in a biologically relevant solvent, without affecting cell viability, open

230 , it is important to link health and climate-relevant soot (black carbon) emission characteristics to

231 These findings suggest a clinically relevant spectrum of subclinical primary aldosteronism (

232 een hindered by the piecemeal development of relevant statistical models.

233 d activation remains as the sole kinetically relevant step on Ni-Co, Ni, and Co clusters, but their s

234 Here, using a ReactorSTM, the catalytically relevant structures are identified as two surface oxides

235 s of the Fermi surface of lithium in several relevant structures.

236 Relevant studies that reported associations between stat

237 A total of 28 relevant studies were identified involving 154,052 parti

238 Our literature search identified 10 relevant studies with inconsistent results.

239 nomic Evaluation Database, were searched for relevant studies.

240 However, Mps1's error correction-relevant substrates are unknown.

241 results on skin prick testing and clinically relevant symptoms of rhinitis related to their sensitiza

242 predictions for a wide range of biologically relevant systems.

243 n-coupled receptor that is a physiologically relevant target for endogenous opioid neurotransmitters

244 entified RAC2 as a potential, and clinically relevant, target of miR-32.

245 pts use drugs directed against KIT and other relevant targets in neoplastic mast cells and will hopef

246 ich are validated as direct and functionally relevant targets of miR-141.

247 These data suggest that Shp2 is a relevant therapeutic target in demyelinating diseases su

248 oligonucleotides into the LV in a clinically relevant time frame significantly inhibits TRAF3IP2 expr

249 e/ubiquinol exchange occurs on catalytically relevant timescales, and whether binding/dissociation ev

250 cellular function, and their actions may be relevant to a variety of human diseases as well as human

251 These reactions are relevant to acid rain and aerosol formation.

252 r than dopamine receptor D2, are immediately relevant to antipsychotic effects or represent novel ant

253 first trimester of human gestation) in ways relevant to ASD-associated pathophysiology.

254 , and repetitive motor stereotypies that are relevant to ASD.

255 as gained attention in the last years and is relevant to assess the safety of our consumer products a

256 from children to measure cytokine production relevant to asthma (secondary outcomes).

257 al research articles, and any other articles relevant to BIA-ALCL were included.

258 cell physiology, how inorganic elements are relevant to cellular pluripotency and differentiation in

259 Receptors relevant to CNS disorders typically have associated prot

260 hunter-gatherer population, convey messages relevant to coordinating behaviour in a foraging ecology

261 paration performance with buffer exchange is relevant to detection of currently unmeasurable protein

262 pecific sites on chromatin to regulate genes relevant to disease progression.

263 red effects of gene-environment interactions relevant to drug response and immunity, and we highlight

264 arry over and influence physiological traits relevant to fitness in black-tailed godwits Limosa limos

265 nal connectivity of dorsal striatal networks relevant to food craving and weight gain.

266 PATCH3 protein was detected in human tissues relevant to glaucoma (e.g., ciliary body).

267 ategy for identifying the Treg cell antigens relevant to human autoimmunity.

268 We conclude that, at concentrations relevant to human exposure and within a particular narro

269 the conditions used in this new approach are relevant to liquid laundry formulations, whereby enzymes

270 in barrier dysfunction in psychosis might be relevant to many aspects of disrupted neuronal and synap

271 ase precession to include object information relevant to memory and behavior.

272 into merrillite by shock-compression levels relevant to meteorites, including Martian meteorites.

273 nutritional stress, a characteristic that is relevant to organismal viability in evolution and in mod

274 rength of eQTLs may help identify cell types relevant to pathophysiology and the regulatory networks

275 lence worldwide, and more serotype data, are relevant to prevention efforts.

276 Therefore our findings are relevant to studies and screens using VTD to activate DR

277 d, but palladium fluoroenolate intermediates relevant to such reactions have not been isolated or eve

278 development of neurophysiological biomarkers relevant to SZ pathology in order to inform DBS targetin

279 These findings may be relevant to the aetiology and treatment of diverse neuro

280 carcinoma (OPSCC) that was determined to be relevant to the American Society of Clinical Oncology (A

281 ffering waist circumference and likely to be relevant to the association between obesity and reflux d

282 ational switching of benenodin-1 may also be relevant to the biological function of these molecules.

283 ting the Fn.peptide complex at loading rates relevant to the cardiovascular system, varied from the l

284 These findings are relevant to the clinical presentation of acetaminophen-h

285 Are structural changes relevant to the patient?

286 ted issues, and remote monitoring, which are relevant to the practicing cardiologist.

287 is so far of variation in specific EBV genes relevant to these diseases and proposed EBV vaccines.

288 e propose a pathogenesis cascade that may be relevant to understanding early CAVD and envision the ex

289 Our results are relevant to understanding the environment of M. tubercul

290 These concepts are relevant to videos that contain evidence for the persist

291 thers, eicosanoid-forming enzymes as well as relevant transcription factors, allowing us to better un

292 inating CNs from neoplastic nodules may have relevant translational implications in early diagnosis.

293 ransducer system operating at the clinically relevant ultrasound frequency of 274.3 kHz.

294 n consumption, nutritional status, and other relevant variables on individual preferences.

295 based on an automated curve fitting of most relevant vibrational bands to calculate a highly charact

296 d, and ProQuest databases, and hand searched relevant websites, for articles published between Jan 1,

297 ontact angles (>150 degrees) has become more relevant with the increased popularity of super-repellen

298 These findings are relevant within the context of designing soft semiconduc

299 determinants of antigenicity in a clinically relevant xenogeneic biomaterial (i.e. BP) and further va

300 sieves, where some of the most industrially relevant zeolites are found.