ライフサイエンスコーパス: important

1 clustering of gangliosides in lipid rafts is important.

2 uditory cortex to extract these biologically important acoustic structures.

3 ttening of leaves to form broad blades is an important adaptation that maximizes photosynthesis.

4 larger prosthesis implantation and may be an important adjunct to surgical AVR in the transcatheter v

5 ss to tCS may represent a broad-reaching and important advance for future mental health care.

6 various shapes and sizes, which would be an important advance for the field.

7 However, cattle, another important agricultural commodity produced in the region,

8 ic nanoparticles (FONs) for determination of important analytes in aqueous medium.

9 erature and of pressure, as both are equally important and complementary thermodynamic variables.

10 ovel targets for SE therapy and diagnosis is important and necessary.

11 Tuberculosis (TB) is an important and widespread disease of wildlife, livestock

12 ted that Inh2-B1 serves as a therapeutically important "antibiotic-resistance-breaker," which enhance

13 dictate the need for effective prevention as important as for therapies.

14 , called DNA glycation, is quantitatively as important as oxidative damage.

15 First, evidence that thrombin may be as important as platelets to thrombosis at sites of arteria

16 n which hyperkalemia develops is at least as important as the degree of hyperkalemia is in determinin

17 field of inflammation biology and will be an important asset in future anti-inflammatory drug design.

18 s of vision impairment and blindness form an important basis of recommendations in public health poli

19 This is important because HSV-1 reproduction triggered by physio

20 TERPRETATION: Our findings show a clinically important benefit of enhanced social recovery on structu

21 of beta-catenin levels and define PKC as an important beta-catenin interaction partner and signaling

22 ) in the first 200 mum of the intima provide important biochemical information that can supplement IV

23 Shape is an important biomarker for E. gracilis, serving as an indic

24 tial Pulse Voltammetry (DPV) as it is a very important biomarker.

25 ydrophobicity of a monoclonal antibody is an important biophysical property relevant for its developa

26 ions between charged amino acid residues are important both to directly stabilize the A1-GpIbalpha co

27 Thus, it is increasingly important but not yet standard to combine RNA-centric da

28 Emerging wireless options offer important capabilities that avoid some of these limitati

29 Dilated cardiomyopathy (DCM) is an important cause of heart failure.

30 t Enterobacteriaceae have recently become an important cause of morbidity and mortality due to health

31 lures that lead to the deterioration of this important cell population.SIGNIFICANCE STATEMENT Althoug

32 Many important chemical transformations occur in two-phase re

33 rrived at natural product-based agents as an important class of modulators.

34 ecular profiling of tumors is emerging as an important clinical approach.

35 h multiple non-motor symptoms in PD and have important clinical consequences, including therapeutics.

36 our understanding of human CSF flux and open important clinical implications, including concepts for

37 lyposis coli (APC) gene, whose product is an important component of the destruction complex that regu

38 regulating NRT1.1 expression, thus adding an important component to the nitrate signaling network.

39 land obstruction and meibocyte depletion are important components of MGD.

40 The goal of this article was to outline important components of opioid-sparing analgesic regimen

41 haviour of single, individual cells can have important consequences.

42 1971;93(1):1-9) was an important contribution to the understanding of the epide

43 ngs presented at the meeting highlighted the important contributions of TGFbeta family signaling to n

44 Neuroinflammation is an important contributor to Alzheimer's disease (AD) pathog

45 are difficult to detect and profile, but are important contributors to human health and disease.

46 e oxidation coupled to sulfate reduction, an important control on methane releases.

47 In contrast, activity was not an important control on survival during nonextinction inter

48 he endosome is increasingly recognized as an important crossroad for APP and these secretases, with m

49 vergence and dual domestication of these two important cultivated tetraploid cotton species.

50 of explicit proton transport through several important D-channel mutants.

51 However, how the brain implements this important decision heuristic and what underlies individu

52 Since protein glycosylation is an important determinant of cell adhesion, we hypothesized

53 DNA methylation at promoters is an important determinant of gene expression.

54 This study brings to light important determinants of antigenicity in a clinically r

55 We describe here important differences in how the Rb and p107 C-terminal

56 Species invasion is an important disturbance to ecosystems worldwide, yet knowl

57 ed qualitative research was used to identify important domains for the Population, Intervention, Comp

58 e structure of the competitive network is an important driver of biodiversity and coexistence in natu

59 By identifying Nck as an important driver of breast carcinoma progression and met

60 the vStr LFP and that piriform cortex is an important driver of gamma-band oscillations in the vStr

61 were comparable in size to effects of other important drivers related to climate, topography, and la

62 le for safe outpatient management, which has important economic and resource implications.

63 e for NE Atlantic marine macroalgal forests, important ecosystems whose main structuring species is t

64 Basophils are important effector cells involved in the pathogenesis of

65 Findings of our model provide an important element to support the implementation of T cru

66 An important emerging application of Tn-Seq is for identify

67 e set out to identify novel and functionally important endothelial lncRNAs.

68 immunomodulatory impact, serving as a highly important epigenetic system.

69 Frost is an important episodic event that damages plant tissues thro

70 Aroma perception is an important factor driving food acceptance.

71 molecular events in AM but not IM may be an important factor in the reduction of cancer incidence.

72 n of lipid and carbohydrate appears to be an important feature of chronic disorders such as obesity a

73 ted with water) were generally identified as important features throughout the study.

74 , which could explain self-acetylation as an important feedback mechanism to regulate acetyltransfera

75 000 people, versus -0.22 for all cities), an important finding given that cities less than 500000 peo

76 MS with lower baseline Abeta1-42 level is an important finding that will have to be replicated in oth

77 These data are important first steps toward implementation of precision

78 er occurs in animal populations and may have important fitness consequences.

79 hat uptake of miR-155-containing exosomes is important for a proper LPS response.

80 host bacteria and which has been shown to be important for bacterial viability.

81 Epigenetic mechanisms are thought to be important for balancing effector and memory differentiat

82 communication via small molecule signals is important for both symbiotic and pathogenic relationship

83 e APC-dependent RNA subgroup is functionally important for cell migration.Adenomatous polyposis coli

84 that organizes centrosomes and cilia and is important for cell signaling, cell cycle progression, po

85 olving intrinsically disordered proteins are important for cellular function and common in all organi

86 results suggest that these three traits are important for determining drought tolerance, and are lar

87 he processes involved in HCMV replication is important for developing novel treatments.

88 ation of the amygdala by serotonin (5-HT) is important for emotional regulation and is implicated in

89 metabolism of glycerol-3-phosphate (G3P) is important for environmental stress responses by eukaryot

90 the ACC has motor areas and is thought to be important for error detection, the dialogue between thes

91 nce-driven neural circuit remodeling process important for executive control of reward and addiction.

92 deliver cargo and alter the fate of HSPCs is important for exploring such applications.

93 LIZ contributed to TM-TM association and is important for F protein function and pre-fusion stabilit

94 of more mature neurons, we identified genes important for human interneuron differentiation.

95 fluid and solutes into lymphatic vessels is important for maintaining interstitial homeostasis and d

96 novel routes for PTP-selective drug design, important for managing diseases such as cancer and Alzhe

97 epresent a near-complete parts list of genes important for meiosis in fission yeast, providing a valu

98 ortex (ACC, areas 24a and 24b) appears to be important for mood disorders and constitutes a neuroanat

99 mote myelination.Axon-glial communication is important for myelination.

100 , elucidating how cells repair themselves is important for our mechanistic understanding of cell biol

101 Limiting wasteful testing is important for patient safety.

102 As such, we hypothesized that Irf6 is important for proper development of salivary glands and

103 trogen (N) and phosphorus (P) deposition are important for quantifying their impact on forest carbon

104 Assessing liver health may be important for reducing the risk of future CHF events, pa

105 tral tegmental area (VTA) dopamine system is important for reward, motivation, emotion, learning, and

106 Light intensity, spectra, and timing are important for SCN synchronisation.

107 uipment, vehicles, or personnel proved to be important for several livestock epidemics.

108 r the study of molecular-neural interactions important for the operation of the circadian pacemaker c

109 Glucose lowering remains important for the prevention of long-term microvascular

110 ctively slowing down learning on the weights important for those tasks.

111 esence and location in proteins and cells is important for understanding biological function.

112 behaviors of RNA-binding proteins (RBPs) is important for understanding their functional roles in ge

113 he transactivation functions of AR and AR-Vs important for various physiological and disease processe

114 replication, indicating that this pathway is important for viral replication.

115 tes and N-use efficiency of these critically important forests.

116 his study and resultant dataset represent an important foundation for developing a standardized test

117 ively, and can encapsulate an agriculturally important fumigant, cis-1,3-dichloropropene.

118 We showed that Mig-6 has an important function of tumor suppressor via inhibition of

119 e been appreciated for a decade, the equally important functions of cellular lipids in virus replicat

120 n reciprocal transcriptional outputs for >50 important genes.

121 ntities of a KRAS fragment encoding G12D, an important genetic marker for guiding therapy of certain

122 ce has not been resolved to chromosomes, and important genome characteristics have not been defined.

123 a and sequenced genomes from an economically important group of grass species, the tribe Paniceae, to

124 ribute substantially to the understanding of important human diseases.

125 the Flaviviridae family is comprised of many important human pathogens including yellow fever virus (

126 tial tissue, confirmed in patients, may have important implications for biotherapies such as vaccines

127 and when 'phenotype specificity' occurs has important implications for exercise prescription.

128 Our findings have important implications for fundamental understanding of

129 sequence context for alt-EJ repair and have important implications for genome editing and genome evo

130 the homeostasis of primary cilia, which has important implications for human disorders related to pr

131 It also has important implications for the design of lifespan experi

132 al expression of labelled protein, which has important implications for the development of future PAL

133 Our findings have important implications for the understanding of compartm

134 Our findings have important implications for the use of Adelie penguins in

135 Important implications of our findings for engineering s

136 ods of inflammation, these findings may have important implications to understanding the behaviour of

137 rongly connected signaling pathways that are important in advanced CRC.

138 ive safety of ranibizumab and bevacizumab is important in choosing an anti-VEGF drug for the hundreds

139 ticles, which is expected to be particularly important in coastal and agricultural areas.

140 Computational models are increasingly important in confronting and overcoming these challenges

141 ted when the quantum nature of light becomes important in correlated matter-photon problems.

142 ins and the main proteolytic enzymes becomes important in determining the quality of the milk.

143 maintenance of gene silencing, while H2AX is important in DNA damage repair.

144 These may be important in ensuring that excessive chloride secretion,

145 mitochondrial dysfunction and apoptosis are important in idiopathic pulmonary fibrosis and asbestosi

146 caspase-1-activating inflammasomes that are important in immunity to cytosolic bacteria, DNA viruses

147 des produces reactive intermediates that are important in nucleic acid oxidation.

148 hysiology and its relationship to dry eye is important in order to optimize diagnosis and treatment a

149 This process is particularly important in plants, because their sessile nature comman

150 NEIL1, demonstrating that these enzymes are important in regulating cellular NEIL1 steady state prot

151 the interface whose properties are crucially important in samples with a thickness of YIG less than 2

152 consecutive cycles.Antihydrogen studies are important in testing the fundamental principles of physi

153 n S-mediated activation of IL-36gamma may be important in the development of numerous IL-36gamma-driv

154 s of molybdenum-sulfide (Mo-S) compounds are important in the function of materials for various appli

155 hydrophobic triad W1L4L8 that is known to be important in the interaction with centrin.

156 seemingly fundamental limit is increasingly important in the laboratory.

157 sion studies indicate that vpr-1 activity is important in the nervous system, germ line and intestine

158 geneous catalysts, which have dominated this important industrial process for nearly 50 years.

159 rmal nematode development, including the all-important infectious stage.

160 ustic components of animal calls that encode important information about the caller's size and identi

161 This finding provided important information for further understanding the life

162 cessing both contribute to the extraction of important information for social interaction (e.g., pers

163 e offers tremendous potential for extracting important information from complex biochemical data sets

164 gues, this natural glycosylation may provide important insights into diabetes research and therapeuti

165 These results provide important insights into the mechanism underlying eukaryo

166 f these targets for EOC and further provided important insights into the relationship between gene tr

167 Extension of the serum half-life is an important issue in developing new therapeutic proteins a

168 Here we show that drugs that inhibit important kinases in the BCR signaling pathway inhibit a

169 The participants identified important limitations and gaps in scientific methodologi

170 Human tissues are an important link between organ-specific spatial molecular

171 dominant regions, which were in functionally important locations on the DENV NS1 protein and are pote

172 Porous conductive polymers are one of important materials, featuring lightweight, large specif

173 d ROS generation and PARP-1 activation as an important mechanism in Zn(2+)-induced TRPM2 channel acti

174 Thus, our data reveal an important mechanism of how p97 maintains lysosomal homeo

175 Together, these data provide important mechanistic insights into the activation of IL

176 Our study provides important mechanistic neuromuscular insight into walking

177 tion factor and tumor suppressor FOXO3 is an important mediator of apoptosis, but the mechanisms that

178 K) and c-Jun N-terminal kinase (JNK), and an important mediator of autoimmune and inflammatory respon

179 predisposes to the development of clinically important mitral valve regurgitation and mitral valve st

180 her, these findings show that monoamines are important modulators of lOFC excitability and suggest th

181 Thus, our study identifies miR-146a as an important molecular brake that blocks the autocrine IL-6

182 e and that in situ production is unlikely an important net source of MeHg to AOSR snowpacks.

183 Such a strategy may offer an important new approach to the treatment of patients awai

184 process is described for these increasingly important NHC molecules, which are generally considered

185 ing blood profile of alopecia areata (AA) is important not only for treatment advancements, but also

186 dividual carbon nanotubes (CNTs) has been an important open question since the first reports of the s

187 he targeting of PSMA has become increasingly important over the last decade.

188 ll nonenveloped icosahedral viruses that are important pathogens in many animal species, including hu

189 phagy/lysosomal degradation, one of the most important pathways linked to ageing.

190 ors both for the development of ARDS and for important patient-centered outcomes like mortality.

191 sponses to environmental changes describe an important phenomenon in global change research.

192 as the green peach aphid (GPA), which is an important phloem sap-consuming pest of more than fifty p

193 conserved small noncoding RNAs that display important physiological effects through their posttransc

194 uick guide on sighing, a kind of breath with important physiological functions that is also used for

195 Platelets participate in many important physiological processes, including hemostasis

196 lated from natural sources are known to play important physiological roles in the human body.

197 t that live bearing has been a fundamentally important precursor in the evolutionary origins of group

198 HPA axis genetic variation and activity were important predictors of cognition across the entire samp

199 self-assembly in water-based solutions is an important problem of interdisciplinary character that im

200 and low-risk patients and to select the most important prognostic markers.

201 d beta-N-acetyl glucosamine (O-GlcNAc) is an important protein modification that is hydrolyzed by O-G

202 We find that the multiplex topology is an important proxy of the cognitive processes of acquisitio

203 tal interventions may be beneficial for this important public health problem.

204 studies (GWASs) make it possible to address important questions about the genetic architecture of co

205 ritical care patients, along with clinically important reductions in blood pressure.

206 ng, open avenues for research and provide an important reference for diagnosis and treatment.

207 lar insight into walking balance control and important reference values for the emergence of balance

208 tin-related modifier (SUMO) and comprises an important regulator of protein function.

209 These results position MAP4Ks as important regulators of the DLK/JNK signaling pathway.SI

210 These data provide an important resource for studies on the roles of local pro

211 facilitate the growth and development of the important rice pathogen Magnaporthe oryzae in leaf cells

212 parvata lugens Stal) - the economically most important rice pest in Asian rice growing areas.

213 Cholesterol is an important risk factor of atherosclerosis, due to its act

214 in the understanding of pathophysiology and important risk factors both for the development of ARDS

215 e encoded neuronal sodium channel NaV1.2 are important risk factors for autism spectrum disorder (ASD

216 disease (MRD) and genetic abnormalities are important risk factors for outcome in acute lymphoblasti

217 ganism growth and development, suggesting an important role for synonymous codon usage in organism ph

218 signaling downstream of Gq and identified an important role for the PLCbeta-PKCalpha pathway, possibl

219 Because HLA-E plays an important role in antiviral immunity by regulating natur

220 The plant cell wall plays an important role in communication, defense, organization a

221 ders an antiviral state that likely plays an important role in constraining HIV-1 transmission and co

222 Trafficking of mGluRs plays an important role in controlling the precise localization o

223 e of genomic/genetic variation that plays an important role in disease susceptibility.

224 P) 3, a water and glycerol channel, plays an important role in epidermal function, with studies showi

225 at radiative cooling by water vapor plays an important role in governing the depth and amplitude of l

226 or cells to cytotoxic treatments can play an important role in individualized cancer medicine.

227 Circadian clocks play an important role in lipid homeostasis, with impact on vari

228 depletion of intracellular stores and has an important role in many cell types.

229 e-containing molecules and IGF2 and plays an important role in many pathophysiological processes, inc

230 l studies revealed that SLC25A46 may play an important role in mitochondrial dynamics by mediating mi

231 te by the first time that the Igf1r plays an important role in murine asthma, mediating both AHR and

232 characteristics of Arbequina oil and play an important role in newly introduced cultivars.

233 esults suggest that endogenous GDNF plays an important role in regulating the function of dopamine tr

234 Staphylococcus aureus plays an important role in sepsis, pneumonia, wound infections, a

235 RTE can play an important role in the differentiation between malignant

236 s likely that TAVR will play an increasingly important role in the management of these patients.

237 proteases or other proteins and may play an important role in the various beneficial functions of va

238 tion initiation from non-AUG codons plays an important role in various gene regulation programs.

239 ng that intracellular Ca(2+) buffers play an important role in vesicle recruitment in both low- and h

240 Gag protein is N-myristoylated and plays an important role in virus budding.

241 Our findings reveal an important role of litter-leached DOC input in regulating

242 fate (r(2) approximately 0.4-0.5) suggest an important role of sulfate in tracer formation via both p

243 cultured CD11c(+) cells, and highlights the important role of SWAP-70 in Cer dynamics in dendritic c

244 This overview emphasizes the important role played by cross-feeding of intermediary m

245 rude from the leading edge of cells and play important roles in cell motility.

246 stitution geometry of lipophilic groups play important roles in compound-lipid interactions.

247 Recent evidence indicates that lncRNAs play important roles in directing the development of diverse

248 ro-inflammatory cytokine signaling and plays important roles in immune function, while abnormal JAK1

249 ated that long noncoding RNAs (lncRNAs) play important roles in many human diseases.

250 lipase (ATGL)-mediated lipolysis that plays important roles in metabolism, tumor progression, viral

251 bers of the SnRK3 family, and that they play important roles in multiple signalling pathways in vivo.

252 is and innate neuroimmune function, and play important roles in neurodegeneration and brain aging.

253 a large fraction of the human proteome play important roles in numerous cellular functions.

254 B7-CD28 family of ligands and receptors play important roles in T-cell co-stimulation and co-inhibiti

255 Our results also show that PKR and OAS1 play important roles in the ISG15-mediated type I IFN sensiti

256 utated genes (non-SMGs), which may also play important roles in the prognosis of EC patients, has not

257 he influenza A virus M1 and M2 proteins play important roles in virus assembly and in the morphology

258 isosterism of the OH and CF2H groups and the important roles of CF2-H...O hydrogen bonds in influenci

259 Although the important roles of co-opted host proteins in RNA virus r

260 man leukocyte antigen region, which suggests important roles of specific amino acid polymorphisms in

261 , funding challenges, and other factors play important roles, but a rigorous analysis of academic sur

262 er the past 100 years, endophthalmitis is an important sight-threatening complication.

263 (IDP), are prevalent in the cell, including important signaling and regulatory pathways.

264 The environment is important since it enabled life to emerge, and shapes ev

265 This may be important, since the administration of lactate during hy

266 , myeloid cells and their progenitors are an important site of HCMV latency, and one viral gene expre

267 Dried fruits are important snacks and additives to other foods due to the

268 ive efficacy in the RV144 vaccine trial have important societal implications.

269 que, that forms on aquatic plant roots is an important sorbent of metal(loid)s and plays a role in th

270 nt of viral diseases.IMPORTANCE Tomato is an important source of micronutrients in the human diet and

271 Cassava (Manihot esculenta Crantz) is an important staple food crop in Africa and South America;

272 The findings are an important starting point for clinicians considering the

273 ein degradation through ubiquitination is an important step in the regulation of glucose metabolism.

274 ccurate inference of non-canonical pairs, an important step towards accurate prediction of the full t

275 p to 27.4 Tg of carbon per year, and provide important structural components for life in coastal wate

276 An important subset of membrane proteins have globular, cof

277 atients with HFrEF on GDMT, underscoring the important synergy of addressing hemodynamic and neurohor

278 Bacterial enzymes are an important target for antibacterial compounds.

279 of starburst amacrine cells, which may be an important target in the mechanism of complex 1-deficient

280 ymptoms and endoscopic features are becoming important targets of therapy.

281 The rates at which wine consumes oxygen are important technological parameters for whose measurement

282 stems, temporal dynamics are relatively more important than in many systems given that hydroperiod is

283 on access of surrounding households was more important than private latrine access for protecting wat

284 s that persist into mitosis likely represent important threats to genome stability, but experimental

285 onhuman primate shows low background in many important tissues that may be sites of infection such as

286 ler understanding of the virus life cycle is important to aid control strategies.

287 Our results indicate that NADPH oxidase is important to control A. actinomycetemcomitans infection

288 ders such as Parkinson's disease (PD), it is important to examine how AgNPs affect microglial inflamm

289 It is important to find biomarkers and targets to improve meta

290 It then is important to monitor responses to treatment, to quickly

291 dification of graphene-based materials is an important topic in the field of materials research.

292 Among the most important traditional features were age and HRL histolog

293 is an important traditional Tibetan medicinal plant with pharm

294 en several candidate genes and agronomically important traits.

295 An important trigger of the posttraumatic immune response i

296 ent-related mortality, thereby addressing an important unmet clinical need.

297 CPSs are important vaccine targets because they are easily access

298 sequence complementarity to the mRNA for the important viral gene activator ICP0, inhibition of ICP0

299 s in trophic interactions will be especially important when affecting habitat-forming species such as

300 determined by grain length and width, is an important yield component, but our understanding of the