ライフサイエンスコーパス: impair

1 resence is attenuated and mating behavior is impaired.

2 ormally present in wounds, wound healing was impaired.

3 bone morphogenetic protein (BMP) signals are impaired.

4 dour-induced attractive social responses are impaired.

5 apoA-IV gene expression and food intake are impaired.

6 during hospitalization, and 11% (n=174) were impaired 1 month after discharge.

7 lectrolytic lesions in the midbrain severely impair a chicken's ability to discriminate orientations.

8 activation of DNA damage response (DDR) and impaired ability to differentiate into myotubes.

9 I (Gly119Arg and Leu131Arg) variants have an impaired ability to regulate complement activation and m

10 ious studies have shown that lymphadenectomy impairs acquisition of adaptive immune responses and ant

11 misshapen and nucleated erythrocytes, due to impaired actin assembly and cytoskeleton stability.

12 molecules, disrupted glutamate homoeostasis, impaired action of antipsychotics, and development of an

13 w enhancers in embryonic stem cells leads to impaired activation of HoxA genes upon differentiation,

14 Thus, impaired adaptation in cortical sensory circuits is a po

15 on in maximal GABA-evoked Popen , suggesting impaired agonist efficacy.

16 Moreover, impaired AJ activity can account for the endothelial dil

17 Therefore, ageing impairs AJ activity, which appears to reflect Src-induce

18 nificant difference was observed between the impaired and nonimpaired groups in the association of fr

19 he sympathetic skin response of the foot was impaired and sweat gland innervation was reduced.

20 tion of sorted LPS-stimulated MZ B cells was impaired, and aged bumble mice were unable to respond to

21 ssive expansion reduces memory potential and impairs antitumor immunity.

22 nsmission in medial prefrontal cortex (mPFC) impaired appetitive trace conditioning at a 2 s trace in

23 h genetic and physiologic evidence points to impaired arousal responses to hypercarbia and hypoxia, w

24 Moreover, whether such dynamic coupling is impaired as a consequence of brain aging in later life,

25 displayed intact cochlear amplification but impaired auditory brainstem responses.

26 These FYCO1 variants may impair autophagic function, leading to RV formation in s

27 ce, activation of PI3 kinase-mTOR signaling, impaired autophagy, mitochondrial dysfunction, stem cell

28 found increased anxiety-related behavior and impaired aversive learning as well as markedly affected

29 alization of these proinflammatory cytokines impaired bacterial clearance and eliminated host protect

30 owed in vitro that physiologic levels of OSM impair barrier function in differentiated airway epithel

31 This S1 photoinhibition did not impair basic motor patterns, post-perturbation completio

32 stasis, including lack of recovery sleep and impaired behavioral adjustment to a novel task after sle

33 sponses in the MD system were accompanied by impaired behavioral performance.

34 d S1450F in rodents, respectively) displayed impaired binding to membrane-associated guanylate kinase

35 c/hydrophobic residues with Ala dramatically impairs both IAPP self-assembly and hetero-assembly with

36 onation of E286 through the D-channel, which impairs both proton pumping and the chemical reaction.

37 e with knockout of SREBP2 in astrocytes have impaired brain development and behavioral and motor defe

38 eir ligands Fgfs Deleting Fgfr1/2/3 not only impaired bSC dendritogenesis but also abolished glutamat

39 e inhibitor, restored performance in animals impaired by continuous stimulation but did not improve p

40 ing was increased by Gab2 overexpression and impaired by Gab2 deletion via regulation of Jak2 and sig

41 o to investigate single molecule dynamics is impaired by the absence of an efficient way to chemicall

42 ng showed that both targets are functionally impaired by the beta-lactone.

43 coupled import-integration reaction that was impaired by the SECA inhibitor sodium azide.

44 d a mechanism-based SCF partial agonist that impaired c-Kit dimerization, truncating downstream signa

45 fish ncx1 mutant, we explored the impacts of impaired Ca(2+) homeostasis on myofibril integrity.

46 yed diacylglycerol clearance from the PM and impaired Ca(2+)-triggered phosphatidylserine scrambling.

47 e single-molecule level has the potential to impair cargo delivery at locations of microtubule defect

48 TRAIL-R suppression in tumor cells impaired CCL2 production and diminished both lung MDSC p

49 larization toward a regulatory phenotype and impaired CD8(+) T cell allo-reactive responses, includin

50 aining a homeostasis that, if disrupted, can impair cell function and lead to disease.

51 -mediated membrane trafficking, resulting in impaired cell adhesion and migration in vitro.

52 Moreover, CDK20-depleted cells display impaired cell proliferation, defective G2/M arrest and i

53 Impaired CFR was similarly present among women and men,

54 C4 synthase-deficient eosinophils exhibited impaired chemotaxis to CCL19 that was restored by exogen

55 of macrophage-like SMCs in the lesions, and impaired cholesterol efflux.

56 nd that unresolved replication intermediates impair chromosome segregation.

57 deficits lead to poor functional outcome via impaired cognition and increased negative symptoms.

58 neurodevelopmental condition associated with impaired cognitive and adaptive behaviors.

59 Genetic ablation of Zbtb7b impaired cold-induced transcriptional remodeling in brow

60 noids to show that infection with Zika virus impairs cortical growth and folding.

61 DCs from these mice show impaired cross-presentation ex vivo and defective cross-

62 PET revealed impaired CVRC in 8 patients (44%).

63 Our data indicate that Ct infection of ESC impairs decidualisation and alters chemokine release.

64 Impaired delivery of antifungals to hyphae within necrot

65 Jarid2-deficient pancreases exhibit impaired deposition of RNAPII-Ser5P, the initiating form

66 and low birth weight have been implicated in impaired development of the retina.

67 Coronary artery calcification (CAC) may impair diagnostic assessment of coronary computed tomogr

68 M) is a rare cardiomyopathy characterized by impaired diastolic ventricular function resulting in a p

69 Surprisingly, reduced GATA1 expression and impaired differentiation were limited to megakaryocytes,

70 Additionally, with the impaired dilator responses, a modest increase in adrener

71 ates for eyes presenting with PDR and vision-impairing DME, but not for those with PDR without vision

72 E, but not for those with PDR without vision-impairing DME.

73 Therefore, the point mutation on NFU1 impairs downstream cluster trafficking and results in th

74 e imaging (MRI) is hypothesized to represent impaired drainage of interstitial fluid from the brain a

75 erimental data suggest that efferocytosis is impaired during atherogenesis caused by dysregulation of

76 62+/-11 years; 16% (n=237) were cognitively impaired during hospitalization, and 11% (n=174) were im

77 HFpEF, identifying the defective steps that impair each one's exercise capacity (peak Vo2).

78 This finding was associated with an impaired early vascularization and stromal tissue growth

79 olling the expansion of the necrotic core by impairing efferocytosis.

80 ed in a halt of cell proliferation, severely impaired EGFR signaling and the onset of cellular senesc

81 Biochemically mutant mice showed impaired electron transport chain activity and accumulat

82 cultures, which could be alleviated without impairing electrophysiological function, allowing simult

83 al compartments, respectively, supporting an impaired endocytic lipid antigen presentation for T cell

84 In SPPL2a(-/-) B cells, such an NTF impairs endosomal trafficking and BCR signal transductio

85 results in decreased glycolysis, leading to impaired endothelial cell proliferation and migration.

86 Both patients and murine models revealed an impaired epidermal structure, ascribed to aberrant secre

87 Loss of claudin-18 was sufficient to impair epithelial barrier function in 16HBE cells and in

88 nto wounded colonic mucosa was sufficient to impair epithelial wound healing in vivo.

89 Furthermore, we found that a PKA inhibitor impaired ES cell proliferation, tumor growth and metasta

90 in secondary MR, however, is associated with impaired exercise capacity and increased mortality.

91 Transcriptome analysis revealed impaired expression and splicing of genes with essential

92 fulfilled the inclusion criteria (NAFLD with impaired fasting glucose or impaired glucose tolerance)

93 rain had multiple phenotypes associated with impaired Fe-S protein maturation.

94 Mutations impairing flagellar synthesis are inferred to increase D

95 sion of meristem/tissue identity markers are impaired from the "symmetry-breaking" periclinal cell di

96 sive-compulsive disorder (OCD) are caused by impaired frontostriatal function.

97 thromboxane A2 production may contribute to impaired functional dilator and hyperaemic responses at

98 Secondary outcomes were impaired functioning (measured by the WHO Disability Adj

99 CHK2 activation in response to irradiation, impaired G2 checkpoint proficiency and radiosensitizatio

100 Knockdown of Shrm4 in rat severely impairs GABABR activity causing increased anxiety-like b

101 terparts, revealing that these substitutions impair gating through a mechanism independent of orthost

102 mma2 receptors, confirming that alpha1(T47R) impairs gating independently of activation by any agonis

103 ognition, because mutations at this position impaired GEF-mediated nucleotide exchange.

104 by fungal and bacterial infections caused by impaired generation of TH17 cells; meanwhile, some patie

105 In conclusion, SGLT2-I treatment improves impaired glucose effectiveness in the liver and insulin

106 n resultant obesity-related hypertension and impaired glucose intolerance.

107 n of TBK-1 in mice with diet-induced obesity impaired glucose metabolism and AKT activation.

108 sformed and categorized into quartiles) with impaired glucose tolerance (IGT) and gestational diabete

109 -IR]) in a large group of subjects with NGT, impaired glucose tolerance (IGT), and T2DM.

110 lucagon levels are observed in subjects with impaired glucose tolerance (IGT).

111 th control littermates, knockout mice showed impaired glucose tolerance and circulating leptin, GLP-1

112 edentary dams produced female offspring with impaired glucose tolerance compared with offspring of ch

113 ese patients with coronary heart disease and impaired glucose tolerance were randomly assigned (1:1),

114 , HbA1c [-10 g/L (95% CI: -12.90, -7.10 g/L; impaired glucose tolerance) and -6 g/L (95% CI: -8.47, -

115 eria (NAFLD with impaired fasting glucose or impaired glucose tolerance) and were randomly assigned i

116 ese patients with coronary heart disease and impaired glucose tolerance, acarbose did not reduce the

117 mice, resulted in decreased beta cell mass, impaired glucose tolerance, defective insulin secretion,

118 autoantibody-positive at-risk children with impaired glucose tolerance.

119 selective deletion of StarD10 in mice led to impaired glucose-stimulated Ca(2+) dynamics and insulin

120 (-/-) mice, oxidative stress associated with impaired glutathione synthesis and nuclear factor erythr

121 A mot1.3-1 knockout mutant showed impaired growth concomitant with a reduction of nitrogen

122 apoptosis in hypoxic cancer cells as well as impaired growth of tumor xenografts.

123 Overexpressing PEX1 in wild-type plants impaired growth, suggesting that excessive PEX1 can be d

124 is a consequence of P62 accumulation, which impairs H2A ubiquitylation and perturbs ATM signaling.

125 process and deficiencies in the MMP9 lead to impaired healing.

126 odel that exhibits heat-shock (HS) inducible impaired heart regeneration.

127 ss using Zip14(-/-) (KO) mice, which exhibit impaired hepatic zinc uptake.

128 Here we use two independent systems to impair hepatocyte proliferation during liver injury to e

129 A2/3) and CA4/dentate gyrus (DG), as well as impaired hippocampal microstructural integrity.

130 We found that tau deletion leads to an impaired hippocampal response to insulin, caused by alte

131 ic core domain but at the same time markedly impair HIV-1 replication capacity.

132 PD-1 identifies "exhausted" CD8 T cells with impaired HIV-specific effector functions, but its role o

133 PARP inhibition and the D226 mutation impair HuR's PARylation, nucleocytoplasmic shuttling and

134 d reduced pSTAT4, nuclear translocation, and impaired IFN-gamma production.

135 AT1R knockdown impaired IL-1beta-induced IL-6 and IL-8 secretion in cul

136 wn that the gain-of-function mutation of TTP impairs IL-10-mediated negative feedback control of macr

137 tion of PLCgamma/PKC-induced mTOR activation impairs IL-7-mediated B cell development.

138 factors, environmental toxins and stressors, impaired immune responses, mitochondrial dysfunction, an

139 regs in vivo at the start or stop of therapy impaired immune tolerance, highlighting the dependence o

140 IL-33 dysregulated lung Treg cells and impaired immunologic tolerance to inhaled antigens.

141 acking SPN, SLO, and both toxins are equally impaired in ability to cause necrotizing myositis.

142 nity between Sesn2 and AMPK upstream LKB1 is impaired in aged hearts during ischemia (P < 0.05 vs. yo

143 R-mediated canonical NF-kappaB signaling was impaired in all mature naive CVID-derived B cells.

144 binding of the UBXD1 adaptor protein that is impaired in disease; this underlies the potential for re

145 formation of NEMO-containing structures was impaired in fibroblasts from patients with IP carrying t

146 berculosis-specific CD4 T cells was markedly impaired in HIV-infected individuals, compared with HIV-

147 ins full metabolic activity, but is 100-fold impaired in its ability to activate APJ.

148 ils and inflammatory cytokine production are impaired in M-ILK-deficient mice, and activation of epit

149 cose uptake and hypertrophic growth were not impaired in muscle-specific GLUT4 knockout mice, demonst

150 Everyday visual search can be impaired in patients with common eye diseases like glauc

151 ood mononuclear cells was also significantly impaired in RRMS.

152 evelopmental plasticity and connectivity are impaired in sensory systems in DS model mice, that such

153 T)-associated protein of the EMAP family, is impaired in these mice.

154 pro-apoptotic mediators CamkII and Stat1 was impaired in Trpc3-deficient M1 cells, gathering insight

155 Phage-resistant mutants had impaired infectivity.

156 rosclerotic lesion that displays features of impaired inflammation resolution, notably a necrotic cor

157 imal models has revealed that targeting RAGE impairs inflammation and progression of diabetic vascula

158 er-associated rare variant (M2145T) in TGEF2 impaired inhibition by the TGEF2 pleckstrin-homology dom

159 Impaired inhibition of fear or behavioral responses is t

160 se the possibility that septic patients have impaired insulin clearance, which could increase their s

161 tivity display decreased insulin content and impaired insulin secretion.

162 Impaired insulin/insulin-like growth factor-1 signalling

163 , barr2, in beta-cells of adult mice greatly impairs insulin release and glucose tolerance in mice fe

164 Impaired integrin activation on neutrophils is the hallm

165 Reduced p62 levels impair interaction of p62 with Keap1, which further decr

166 s from MetSyn or LPS-injected rats exhibited impaired intrinsic contractile activity and associated i

167 t is similar to wild-type aged hearts (i.e., impaired ischemic AMPK activation and higher sensitivity

168 ethyloxalylglycine (DMOG) also significantly impaired iTreg differentiation.

169 Warming impairs juniper uptake of deep sources during extended d

170 iochemical data indicated that this mutation impairs laminin polymerization, which we hypothesized to

171 Among individuals with impairing late-onset ADHD symptoms, the most common reas

172 its absence, secretory vesicle formation is impaired, leading to accumulation of immature vesicles,

173 ed that recycling of the TCR-CD3 complex was impaired, leading to increased lysosomal targeting and r

174 apoptosis, altered DG cell composition, and impaired learning and memory.

175 However, PPM is associated with impaired left ventricular ejection fraction recovery pos

176 etriotic lesions, which may contribute to an impaired lesion vascularization and growth.

177 y (LAD) syndrome in humans, characterized by impaired leukocyte recruitment and recurrent infections.

178 gatroban is contraindicated in patients with impaired liver function, and activated partial thrombopl

179 xplore the role of natural killer T cells in impaired liver regeneration.

180 Both transiently impaired locomotion through an off-target effect that di

181 Acute consumption (1.34 ng/bee) impaired locomotion, caused hyperactivity (velocity: +10

182 through multiple mechanisms, one of which is impaired lysosomal proteolytic activity.

183 POP2 also impairs macrophage priming by inhibiting the activation

184 Surprisingly, we found that jet lag impaired major parameters of home-team offensive perform

185 est that ribosomal deficiency contributes to impaired megakaryopoiesis in myeloproliferative neoplasm

186 Knocking down Elmo1 impairs metastasis of carcinoma cells to the lung, there

187 These unexpected findings suggest that impairing microglial TREM2 signaling reduces neuroinflam

188 Impaired mitochondria and accumulated H2O2 production re

189 effect), extensive glutamine utilization and impaired mitochondrial electron flow.

190 he mitophagy mediators BNIP3 and BNIP3L, and impaired mitophagy.

191 at the central retinal lesions either do not impair motion detection or even result in better perform

192 : +44%) shortly after exposure (30 min), and impaired motor functions (falls: +83%; time top: -43%; t

193 ng development and degeneration in adulthood impairs motor function.

194 t data, rendering clinical interpretation of impaired movement patterns sub-optimal.

195 e marrow adiposity, decreased bone mass, and impaired MSC self-renewal capacity in mice.

196 allergy development, possibly indicating an impaired mucosal barrier function in allergic children.

197 We sought to determine the role of impaired mucus clearance in the pathogenesis of allergen

198 rmal spectra of basic behavioral activities, impaired muscle grip strength, and defects in motor coor

199 tion with Cobra Venom Factor (CVF) result in impaired muscle regeneration following cardiotoxin-induc

200 Moreover, loss of SEP4 severely impaired mutant conidiation, melanin and chitin accumula

201 ption of Myc function or sterol biosynthesis impaired myeloid differentiation.

202 m levels in HFpEF are neither a result of an impaired Na(+) gradient nor expression changes in key io

203 te receptor 1 (Folr1; also known as FRalpha) impairs neural tube formation and leads to NTDs.

204 ses a spectrum of brain malformations due to impaired neuronal migration in the developing cerebral c

205 mitant with reduced NMDA-evoked currents and impaired NMDAR-dependent insertion of GluA1 at stimulate

206 PK2 levels or activity could be exploited to impair NRF2-mediated signalling in cancer cells, and thu

207 OS dysfunction, as indicated by the level of impaired O2 extraction from arterial blood during peak e

208 Mutants lacking TAG or impaired of TAG hydrolysis show spore wall assembly defe

209 ary cells revealed one substitution severely impaired OGFOD1-dependent hydroxylation of a neighboring

210 determination of RNE cells and consequently impairs optic cup formation.

211 rated that senescent-cell conditioned medium impaired osteoblast mineralization and enhanced osteocla

212 This process is thought to impair osteogenic and hematopoietic regeneration.

213 earch has linked age-related hearing loss to impaired performance across cognitive domains and increa

214 Se doses (32.5 and 57.5 mug Se/g) exhibited impaired performance in the latent learning task.

215 ronment, elevating interstitial pressure and impairing perfusion.

216 by the Confocal Leak Score (CLS; range: 0=no impaired permeability to 100=complete loss of barrier fu

217 2-expressing macrophages were accompanied by impaired phosphorylation of IL-1R-associated kinase 1 (I

218 aves of polyprenol-deficient plants revealed impaired photosystem II operating efficiency, and their

219 r people face a high risk of muscle loss and impaired physical function, which may contribute to sarc

220 When combined with mutations that impair plastid gene expression (prors1-1, prpl11-1, prps

221 Depletion of satellite cells impaired post-burn recovery of both muscle fibre cross-s

222 " crossed the fixed threshold from intact to impaired pressure reactivity (pressure reactivity index

223 The presence of Retro94 results in severely impaired production of infectious virions, with a decrea

224 icating a possible mechanism contributing to impaired proliferative capacity of M. tuberculosis-speci

225 humoral response in immunized mice does not impair protection from a homologous challenge; however,

226 We observed reduced myotube diameter, impaired protein synthesis, and increased autophagy flux

227 resources to averting disaster, however, can impair quality of life, as in anxiety and paranoia.

228 Impaired RDD and allodynia were present in type 1 and ty

229 We have investigated the pathogenesis of impaired RDD in diabetic rodents exhibiting features of

230 riate expression of MMP9 also contributes to impaired re-epithelialization.

231 us challenge; however, it does significantly impair recovery from a heterologous challenge virus, hig

232 inment in MARCO(-/-) mice was accompanied by impaired recruitment of Ly6C(high) monocytes and monocyt

233 Lgr5(Creert2)/Met(fl/fl)/LacZ mice had impaired regeneration of MET-deficient ISCs.

234 es is an important source of stress that may impair reliability of test responses.

235 ypothesized that the hepatokine fetuin-A may impair renal function in non alcoholic fatty liver disea

236 tive efferocytosis and its possible links to impaired resolution in atherosclerosis are incompletely

237 The impaired response propagation from the stimulation site

238 with unrestrained fibroblast proliferation, impaired scar remodeling, reduced fibroblast-derived col

239 Impaired signaling via CX3CR1, the fractalkine receptor,

240 etylation of DNA-damage response proteins by impairing SIRT2 catalytic activity or protein levels but

241 paired spatial tuning of neural activity and impaired sparse coding of information, and deficits in t

242 mPFC inactivation did not impair spatial learning or retrieval per se, but impaire

243 Disruptions in circadian timing impair spatial memory in humans and rodents.

244 lope of the "inverted-U" input-output curve, impaired spatial tuning of neural activity and impaired

245 Repeated cell divisions and aging impair stem cell function.

246 Importantly, AZD4547 impaired stem cell-like characteristics in primary MECs

247 ose lowers whole-body glycogen synthesis and impairs subsequent exercise performance, presumably beca

248 This dimeric ERdj3 shows impaired substrate binding both in the ER and extracellu

249 In turn, this impaired SUFU-mediated repression of the SHH pathway, as

250 etreatment can sensitise cells to stress and impair survival.

251 The effect of an impaired sweet-taste perception system on cognition func

252 elated and non-combat related mental stress, impaired sympathetic and cardiovagal baroreflex sensitiv

253 ze to the presynaptic compartment but do not impair synaptic function in fly neurons.

254 fering with AMPAR surface diffusion markedly impairs synaptic potentiation of Schaffer collaterals an

255 ficiency (SCID) is characterized by severely impaired T-cell development and is fatal without treatme

256 rneurons, even transiently during the delay, impaired task performance, primarily by increasing inapp

257 n in the Pnpla3(148M/M) mice being caused by impaired TG mobilization from LDs.

258 Furthermore, PFT-mu administration did not impair the anticancer efficacy of cisplatin and radiothe

259 The frameshift promoting signals mostly impair the EF-G-catalyzed translocation step of the two

260 cell lines carrying genetic aberrations that impair the Hippo signaling pathway showed heightened sen

261 Serotonin depletion impaired the ability of exendin-4, a clinically used GLP

262 Finally, whole OSPW also impaired the ability of RAW 264.7 cells to perform phago

263 ir spatial learning or retrieval per se, but impaired the ability to follow changing spatial rules.

264 Gi-DREADDs in the basolateral amygdala (BLA) impaired the acquisition of both conditioned fear extinc

265 The absence of functional PNPLA1 in mice impaired the formation of omega-O-acylceramides and led

266 Mutations in ARTEMIS-deficient patients impaired the interaction with the C terminus and also af

267 netic ablation of sensors of apoptotic cells impaired the proliferation of tissue-resident macrophage

268 us LGI4 transcript and in a cell-based assay impaired the secretion of truncated LGI4 protein.

269 f extreme water-level events in the Tropics, impairing the developing economies of equatorial coastal

270 drug-resistant tumors to Enz by selectively impairing the GR signaling axis via this enhancer.

271 antibiotics may impact protein synthesis by impairing the recognition of peptidyl-tRNA in the small

272 Aging impairs the ability of alveolar macrophages to limit lun

273 ization signal and that nuclear localization impairs the ability of ICAP1 to suppress integrin activa

274 erimental autoimmune encephalomyelitis (EAE) impairs the accumulation of inflammatory monocyte-derive

275 TET2 and TDG downregulation impairs the acquisition of such differential histone mod

276 ression of the host phosphatase PPM1A, which impairs the antibacterial response of macrophages.

277 ne deacetylase corepressor complex, severely impairs the competitive repopulation capacity of HSCs.

278 Obesity impairs the relaxant capacity of adipose tissue surround

279 found that a deletion in the p27-p55 operon impairs the replication of M. bovis in bovine macrophage

280 However, despite conscious access being impaired, the ability to decode the presence of integrat

281 xtensive long-term culture-induced MSC aging impaired their osteogenic ability and subsequent bony ca

282 the intracellular trapping of receptors and impairing their access to the dendritic surface and spin

283 However, the exact reasons impairing their commitment remain elusive.

284 rated or have permissive inclusion criteria, impairing their use.

285 ematopoietic stem cells (HSCs) progressively impairs their homeostasis in the bone marrow through an

286 that macrophage-specific deletion of ERalpha impaired this M2 polarization.

287 and/or increased insulin resistance (IR) or impaired tissue metabolism is unknown.

288 Patients were impaired to the same extent in the No-Rotation and Rotat

289 atures between patients in XP subgroups with impaired transcription coupled nucleotide excision repai

290 ORF7 deletion also impaired transmission of ORF7-deficient virus among the

291 sm in ECs did not cause energy distress, but impaired tricarboxylic acid (TCA) cycle anaplerosis, mac

292 ylation of PTK6 Y342, and disruption of Ptk6 impairs tumorigenesis.

293 , activation of AMPK signaling in muscle was impaired under starved conditions, while mTORC1 signalin

294 delay disease onset but become functionally impaired upon disease progression.

295 unx3 deficiency limited clonal expansion and impaired upregulation of cytotoxic molecules in TEFF cel

296 ty in the hypertrophic chondrocyte layer and impaired vascular invasion.

297 Obese patients have impaired vasodilator reactivity and increased endothelin

298 ized by ritualistic-repetitive behaviors and impaired verbal/non-verbal communication.

299 adaptive immune response is associated with impaired viral clearance in Nlrc5(-/-) mice.

300 oite colonization in the small intestine and impaired weight gain.