ライフサイエンスコーパス: handle

1 on of death by neurologic criteria easier to handle.

2 ced instruments, easy to prepare and easy to handle.

3 at our natural immune system cannot normally handle.

4 ine (GlcNAc) residue to act as an 'acceptor' handle.

5 re was rapid, eco-friendly, safe and easy-to-handle.

6 maturity (6 to 7 months old) and are easy to handle.

7 ture matrices that are statistically hard to handle.

8 ressure and are therefore considered safe to handle.

9 generally expensive and require expertise to handle.

10 th force spectroscopy that require molecular handles.

11 zation (iMALDI) assays with automated liquid handling.

12 o postulate defects in intracellular calcium handling.

13 though responses were more variable for cup handling.

14 ling; both signalling pathways affect Ca(2+) handling.

15 havioural tests compared to traditional tail handling.

16 ration via effects on glucose metabolism and handling.

17 ubstrate, Raman labels or complicated sample handling.

18 esting that EHD4 plays a role in renal water handling.

19 volume ratio, low cost, and easy preparation/handling.

20 uent, but little is known about its cellular handling.

21 metabolomic signatures of perturbed nitrogen handling.

22 hildren who see a movie containing guns will handle a real gun longer and will pull the trigger more

23 3%) reported they would not feel comfortable handling a situation in which a pediatric patient's fami

24 ge within with capillary networks, and fluid handling across the microcirculation are compelling aven

25 lopment of web-based bioinformatics tool for handling all studies which include next generation seque

26 n gradients, eliminates complex microfluidic handling, allows for incorporation of additional tumor c

27 dysfunction, dampened intracellular calcium handling, alterations in cardiac morphology, and elevate

28 As our cell balance is easy to handle and compatible with fluorescence microscopy, we a

29 These precursors are stable, easy to handle and facilitate direct and regioselective (18) F-l

30 rs and are more stable, soluble, and easy to handle and purify.

31 ll radii (such as </=125 nm) are delicate to handle and should be laid down on a solid substrate to o

32 of magnitude, they remain easily suspended, handled and administered through standard microcatheters

33 vity, which correlated with altered Ca(2)(+)-handling and action potential (AP) prolongation.

34 Disturbances in cellular Ca(2+)-handling and alterations in Ca(2+)-dependent gene expres

35 The precision handling and analysis reveals a capacity to assay sparin

36 hese data harbor, a robust and scalable data handling and analysis solution is desired.

37 in treatment on cardiac function, [Ca(2+) ]i handling and cellular electrophysiology, which participa

38 se of leptin on cardiac function, [Ca(2+) ]i handling and cellular electrophysiology, which participa

39 ic reticulum Ca loss that mediate altered Ca handling and contractile dysfunction associated with sep

40 e the serious environmental corrosion during handling and cycling.

41 indings highlight alternative strategies for handling and export of amyloid protein sequences.Gram-ne

42 ERCA2a) in the regulation of overall calcium handling and heart muscle contractility.

43 raining exerts positive effects on substrate handling and improves insulin sensitivity.

44 oteasome impairment, such as altered calcium handling and increased oxidative stress due to mitochond

45 of experimental periodontitis with favorable handling and inflammation-responsive characteristics.

46 attributed primarily to contaminations from handling and machining of the plastics, and were not ide

47 ive CASQ2 mutations, causing abnormal Ca(2+)-handling and malignant ventricular arrhythmias.

48 owledge, necessitating novel methods of data handling and modelling.

49 to the hippocampus of epileptic mice rescued handling and open field deficits starting at 60 DAT.

50 Behavioral testing (handling and open field), continuous video-electroenceph

51 s immediately prompts young monkeys to start handling and percussing nuts, and they continue these ac

52 Variables due to animal handling and physiology, such as anatomic placement and

53 n the same vessel, avoiding excessive sample handling and reducing energy expenditure by more than te

54 anding the subtleties is the key to the safe handling and separations of the highly radioactive nucle

55 garnered much interest due to their ease of handling and solution processability.

56 Elderflower seasonality implies proper handling and storage conditions, for further processing,

57 om its low density, and therefore, efficient handling and storage methods are key factors that need t

58 ice viability, maximum contractility, Ca(2+) handling and structure.

59 tment, have variable effects on renal sodium handling and the hypertensive response, accruing from th

60 y involvement in the kidney defect in sodium handling and the pathogenesis of salt-sensitive hyperten

61 ciated with altered insulin response/glucose handling and thermogenesis occurred prior to any functio

62 ion of conjugates with fluorophore, affinity handle, and pharmacological agents.

63 oice of metabolomics techniques, biospecimen handling, and data analysis; (3) application to studying

64 ch as a large light-coupling tolerance, easy handling, and delivery of higher light power without und

65 transformed by advances in computing, sample handling, and imaging techniques, but high-resolution ex

66 her this is because of low intake or altered handling, and it is also unknown whether variation in ci

67 To improve the sample handling, and reduce cost and preparation time, of pepti

68 contribute to duplex and single-stranded DNA handling, and test the cellular consequences of partial

69 expensive chaperones), comprehensive (it can handle any type of protein), and economical (the chapero

70 rkable new roles for mitochondria in calcium handling, apoptosis, heme turnover, inflammation, and ox

71 configurable channels for nonstandard liquid handling applications.

72 cardial calcium (Ca(2+)), and sodium (Na(+)) handling, as well as ion transporter expression and test

73 lation of a versatile, nucleophilic coupling handle at a previously inaccessible site of 2,1-borazaro

74 ogies wherein only one spin species could be handled at a time.

75 nology, a magnetic-bead extractor is used to handle beads from 96 wells simultaneously.

76 Safe patient handling behaviors and lift use were examined for the re

77 In bivariate analysis, high safe patient handling behaviors were associated with shorter height,

78 iable logistic regression, high safe patient handling behaviors were significantly associated with a

79 Importantly, MAJIQ-SPEL is able to handle both classical (binary) and complex, non-binary,

80 i) it is practically important to be able to handle both paired and unpaired samples; and (iii) the c

81 We have implemented DNNs to handle both problem transformation and algorithm adaptio

82 This in turn improved dough handling, bread crumb texture and crust color.

83 Here we establish whether non-aversive handling, brief prior familiarisation with the test aren

84 ) generates datasets that are challenging to handle by current genetic mapping software with graphica

85 cal user interfaces (GUIs) of equipment, are handled by means of image recognition tools provided by

86 Reabsorption is primarily handled by SGLT2, and SGLT2-specific inhibitors, includi

87 id growth in the number and size of datasets handled by the system.

88 ften very expensive, tedious and can only be handled by trained personnel.

89 By contrast, those handled by tunnel explored readily and showed robust res

90 r sealing defects introduced during transfer/handling by interfacial polymerization, a facile oxygen-

91 er systemic lipolysis, and better fatty acid handling by lean tissues.

92 ur work reveals the specificity by which the handling by NCLX of calcium exchange can map to neural c

93 erved across replicates and facilitates data handling by preprocessing all replicates in a single ste

94 ociation with dysregulated lipid and glucose handling by the dam.

95 2 is assumed to have a critical role in salt handling by the thick ascending limb.

96 cathepsin K and those associated with Ca(2+) handling, calcineurin/NFAT signaling, insulin signaling,

97 iology data supporting the role for NCX-9 in handling calcium exchange at the mitochondrion.

98 nding nanoparticles with these radiolabeling handles can have dramatic effects on important propertie

99 Our study shows that non-aversive tunnel handling can substantially improve mouse performance in

100 s (ROS) negatively affect myocardial calcium handling, cause arrhythmia, and contribute to cardiac re

101 obust supportive data, partly because of the handling characteristics of traditional coronary pressur

102 ramework (MOF) to produce stable and safe-to-handle Co(III) materials featuring terminal Co(III)-halo

103 osis, cardiomyocyte hypertrophy, and calcium handling (Col1a2, Nppa, and Serca2).

104 to scans based on cell growth or binding and handles common experimental errors.

105 Compared to existing approaches, CMINT can handle complex lineage topologies, capture higher qualit

106 efficient population genetics simulator that handles complex evolutionary and life history scenarios

107 obial nanocellulose wicking membrane (sample handling component).

108 ontrol circuitry, the construction of liquid-handling components and the creation of the MACS microfl

109 Moral philosophy, however, can handle contemporary biomedical issues.

110 Difficulties in generating and handling data for large volumes at nanoscale resolution

111 capture efficiency and obstruction of liquid handling devices.

112 rmore, Nrf2 activated distinct mechanisms to handle different misfolded proteins.

113 l reengineering of NRPSs by swapping domains handling different substrates to generate novel natural

114 hondrial signaling to the etiology of copper handling disorders.

115 take nor body weight but it improved glucose handling, displaying tissue-specific beneficial actions.

116 off-stoichiometric intermediates as one such handle driving polymorph selection in the diverse class

117 MS was estimated by using a handle dynamometer on 1,950 children and adolescents fro

118 that, by installing a sufficiently reactive handle (e.g., a C-Br bond) and developing compatible mil

119 c nanoparticles hold great promise as photon handling elements and as channels for coherent transfer

120 bril density and alignment, improved calcium handling, enhanced contractility, and more physiological

121 d origin, followed by DNA extraction, sample handling environment, and bioinformatics.

122 seek to compare the modeling approach which handles event types as separate, correlated end points a

123 unction, but little is known about how cells handle excess fuels to avoid toxicity.

124 ess the latter by using a set of storage jar handles (fired clay) stamped by royal seals as part of t

125 y gate NADPH-binding, implicitly providing a handle for activating/deactivating the very first step i

126 Solution pH provides a convenient handle for controlling the potential of these two proces

127 ile preserving the olefin functionality as a handle for further chemical elaboration.

128 The fluorinated indazole group offers a handle for further functionalization and tuning of its p

129 lly active molecules, and offers a synthetic handle for further manipulation.

130 tracellular fate of siRNA and may serve as a handle for improving the efficiency of delivery.

131 g in a sequential manner, as well as a click-handle for subsequent functionalization.

132 ation of CTL function provides a biochemical handle for understanding the relationship between FtsZ-r

133 s are too weak to be sutured or conveniently handled for clinical applications.

134 lso hold the potential to provide orthogonal handles for biochemical isolation of native protein comp

135 Furthermore, handling for hyperstacks, 3D reconstruction and batch pr

136 lternative splicing transitions, and calcium-handling functions are significantly enriched among gene

137 CT-developed force and expression of calcium-handling genes (eg, SERCA2a, L-type calcium channel).

138 Difficulties associated with handling H2 and CO in metal-catalyzed processes have led

139 h malaria susceptibility, and perturbed iron handling has been hypothesized to contribute to the pote

140 Since altered brain lactate handling has been implicated in the development of impai

141 The azide handle in Aha can be selectively conjugated to dyes and

142 ecific non-covalent and paratope-independent handles in targeted drug delivery, molecular imaging, an

143 vents have been attributed to perturbed Ca2+ handling in cardiac myocytes leading to spontaneous Ca2+

144 hannels that provide counter ions for Ca(2+) handling in intracellular stores.

145 us a novel target for influencing metabolite handling in junctionally-coupled tumours.

146 The robotic system combines chemical handling, in-line spectroscopy and real-time feedback an

147 increased harm, including disruption in iron handling, increased extravascular hemolysis, and the for

148 e to promote safe work practices for patient handling injury prevention.

149 enables introduction of an orthogonal alkyne handle into monoclonal or polyclonal antibodies from dif

150 mino acids bearing chemical tags or affinity handles into peptidoglycan precursors, including Lipid I

151 provides an overview of how these cell types handle iron, highlighting how iron and heme transporters

152 otoneuron development and indicate that mRNA handling is a critical component of SMA.

153 Defective Ca(2+) handling is a key mechanism underlying hepatic endoplasm

154 Automated and reproducible sample handling is a key requirement for high-throughput compou

155 Altered Ca(2+) handling is often present in diseased hearts undergoing

156 The sample handling is very rapid and reproducible, and much less t

157 Patient handling is well known for the risk of musculoskeletal i

158 hensive miRNA profiling strategies to better handle isomiRs and summarization based on each nucleotid

159 has faced challenges due to difficulties in handling issues of statistical reliability and robustnes

160 there to orchestrate the events necessary to handle it.

161 ent tools (RDP Classifier, UTAX, and SINTAX) handle ITS fungal sequence data.

162 Handling laboratory animals during test procedures is an

163 rence methods have been developed, which can handle large data.

164 ave been improved, evaluated, and adapted to handle large datasets.

165 SurvivalGWAS_SV is able to handle large scale genome-wide data, allowing for impute

166 , more rapid and efficient methods which can handle large-scale problems still need to be developed.

167 bioinformatic and chemoinformatic tools for handling large-scale metabolomics data, methods for eluc

168 Therefore, Balaur can enable institutions handling massive genomic data sets to shift part of thei

169 This includes calcium and phosphate-handling mechanisms linked to lead and arsenic contamina

170 taneous measurements of mitochondrial Ca(2+) handling, membrane potential, respiratory rate and produ

171 To understand how the brain handles mentally represented information flexibly in the

172 We reasoned that interactomes of molecules handling metals in neurons should include novel metal ho

173 Tail handled mice showed little willingness to explore and in

174 for continuous droplet screening, passively handling millions of droplets with complete uniformity,

175 ed from the same set of subjects, and easily handle missing values without any imputation.

176 Incorrectly handling missing data can lead to imprecise and biased e

177 e effect of applying different approaches to handling missing data in an analysis of the association

178 low for real-time results generation and (2) handling missing data is still challenging.

179 attention to characterizing uncertainty and handling missing data should be taken into account when

180 genome variant calling and annotation do not handle mitochondrial genome data appropriately.

181 long treatment times can cause difficult-to-handle modifications to the cellular redox buffer which

182 It therefore can be handled more facilely using biosafety level 2 practices.

183 le data (PLATO), a software tool equipped to handle multi-omic data for hundreds of thousands of samp

184 Here, we extend MS2LDA to handle multiple metabolomics experiments in one analysis

185 SiNVICT has the capability to handle multiple sequencing platforms with different erro

186 that extends our previous method (HapCUT) to handle multiple sequencing technologies.

187 feature selection approach, which is able to handle multivariate temporal data without previous data

188 roaches developed for microarray data cannot handle multivariate temporal data without previous data

189 en separated from their mothers (but not non-handled mycobiome) restored hypersensitivity to distensi

190 In contrast, neither handling nor pDNA-IL-10 treatment alters self-administra

191 from their mothers (hypersensitive) with non-handled (normally sensitive) rats.

192 rter periods than the more common actions of handling nuts.

193 fferent liganded states and can be used with handles of different lengths.

194 low-cost disposable microfluidic chamber for handling of biological samples, is highly desirable.

195 The safe handling of category A infectious substances is a unique

196 Continuous flow synthesis enables the safe handling of diazoalkanes at elevated temperatures, and t

197 readily observed in the highly dynamic iron handling of four main cell types: duodenal enterocytes,

198 a "reaction in the beaker", avoiding direct handling of highly toxic fluorine gas.

199 However, the handling of magnetic particles inside microfluidic chips

200 ins is the source of the need for a specific handling of membrane proteins, which transpired in the c

201 ue preparation, slicing with a vibratome and handling of myocardial slices.

202 pler, optimal vibratome settings and correct handling of myocardial slices.

203 Proper handling of samples and data will reduce the need for us

204 nclude choosing of appropriate cell numbers, handling of the cells, selection of recipient animals an

205 rturn common beliefs and call for a specific handling of their diffraction data.

206 cultivation of poppies or the collection and handling of their latex.

207 provided by Sikuli scripting language, while handling of their physical counterparts is achieved usin

208 e investigated whether obesity alters Ca(2+) handling of these neurons in mice.

209 It includes several new major features: (i) handling of very large genotyping datasets like the ones

210 The efficient handling of wastewater pollutants is a must, since they

211 age substantial computational resources, the handling of which requires specific programing skills.

212 ge of automated and passive methods of fluid handling on a chip.

213 ture sensitive reagents that require special handling or harsh reductants that limit functionality.

214 roused at night by sleep deprivation (gentle handling) or caffeine treatment that both prevented slee

215 negative binomial model, and can efficiently handle over-dispersion and varying total reads.

216 n atom is considered to be an ideal coupling handle, owing to its relative abundance in organic molec

217 dulation, leading to normalization of Ca(2+) handling parameters.

218 able in the droplet microfluidics toolbox to handle particles encapsulated inside droplets and to man

219 developing fast, portable, cheap and easy to handle pesticide detection platforms are getting attenti

220 The needs for data management, handling population structure and related samples, and p

221 of conventional motif-visualization tools in handling positional interdependencies and utilizing rank

222 lly, Bi(OTf)3 serves as a stable and easy to handle precursor to TfOH.

223 Previous work has shown that a neonatal handling procedure in rats (which promotes enriched mate

224 le characteristics greatly simplified sample handling procedures.

225 extraction, which greatly simplifies sample handling procedures.

226 bules and vacuoles displayed distinct Ca(2+)-handling properties.

227 ti-location proteins and (iii) being able to handle proteins of multiple organisms, including Eukaryo

228 onal activity and DA neuron expression of FA-handling proteins and FA uptake.

229 dition, acquired deficits of multiple Ca(2+)-handling proteins can contribute to the pathogenesis of

230 ) release, and sarcoplasmic reticulum Ca(2+) handling proteins in post-infarction remodeled hearts.

231 d, and expression levels of Ca(2+)- or Na(+)-handling proteins were not altered.

232 e synthase and sarcoplasmic reticulum Ca(2+) handling proteins, and identify a new therapeutic target

233 expression of sarcoplasmic reticulum Ca(2+) handling proteins.

234 logy laboratory designed and validated waste-handling protocols with simulated patient trash to ensur

235 egimens reflective of current corneal tissue handling protocols.

236 Afterward, handling ratings and catheterization times were obtained

237 in each vessel region, and visualization and handling ratings were measured for the MR imaging guidew

238 rofiling of the nucleus accumbens (NAc) from handled rats following repeated exposure to remifentanil

239 oding IL-10 (pDNA-IL-10) into the NAc of non-handled rats.

240 parated from their mothers compared with non-handled rats.

241 erein is described a readily synthesized and handled reagent class which can accomplish the controlle

242 ion in which message-passing-based inference handles recognition, segmentation, and reasoning in a un

243 cyte size reduction and fatty acid metabolic handling remain unknown.

244 ized building block which bears a functional handle required for Staudinger ligation on solid support

245 tom analytical tools with nonstandard liquid handling requirements and provides an ergonomic alternat

246 mproves process safety and mitigates product handling requirements.

247 erimental setup based on the use of a liquid-handling robot and automated data acquisition allowed fo

248 Liquid-handling robots have many applications for biotechnology

249 fulfills important roles in whole-body lipid handling, serves as the body's major energy storage comp

250 dietary BPA exposure, six male participants handled simulated receipts containing relevant levels of

251 er genes, an ability to adjust the method to handle slow- and fast-evolving tumors, and a computation

252 Molecular iodine, an easy to handle solid, has been successfully employed as a cataly

253 Os, and indicate optimal sequencing and data-handling solutions for each case.

254 , existing computational methods designed to handle specific technologies do not scale well on data f

255 ment of the Mtb 23S rRNA, named H54a or the 'handle', switches interactions from with rRNA helix H68

256 duce risk of injury while performing patient handling tasks.

257 New specificities of nucleic acid handling that underlie the catalytic cycle of repeat syn

258 There is a need to better understand and handle the 'dark matter' of proteomics-the vast diversit

259 allenge for centers that may not be ready to handle the additional workload and financial burden asso

260 The workflow is flexible enough to handle the complex barcoding schemes used in many immuno

261 To handle the confounding effect of SCT that could occur in

262 the scleral lens because of an inability to handle the lenses, and 40 eyes wore the lenses at their

263 radigms, to ensure the software's ability to handle the requirements of modern science.

264 ethodology and software that can efficiently handle the scale and complexity of genetic data from GWA

265 veolae in muscle tissue have the strength to handle the stress of muscle movement.

266 e by utilizing common tools that are able to handle the varied requirements of each MHC-group.

267 et al. (2017) shed new light on how the skin handles the activation of oncogenic pathways in the stem

268 e account of how the human brain dynamically handles the flow of proprioceptive information and conve

269 Patient preferences regarding which provider handles the following care needs after treatment were as

270 The workflow robustly handles the high numbers of artifacts present in mate-pa

271 lation theory, consisting of a framework for handling the structure of multiorbital correlations, a t

272 ned, leading to correlated motions among the handle, the L1 stalk and the small subunit in the rotate

273 ients' preferences regarding which providers handle their care needs after primary cancer treatment.

274 produced potent detoxification mechanisms to handle these situations.

275 The responsibility of handling these dead cells falls on phagocytes of the imm

276 alytical tools are obsolete when it comes to handling these large datasets.

277 D, Big Data Regression for predicting DH, to handle this high-dimensional problem.

278 Computational models suggest that the brain handles this by reducing neural connections to the previ

279 udies led to conflicting results and did not handle time-dependent covariates and history of treatmen

280 e aliphatic tail length (i) can be used as a handle to systematically tune the helical pitch from 80

281 ed as easily tunable and reversible chemical handles to hybridize the protein-DNA conjugates onto the

282 Finally, we use two orthogonal DNA handles to regulate two different bioactive signals, wit

283 at integrates the covalent attachment of DNA handles to target proteins with a selection step for fun

284 ptical tweezers requires attaching molecular handles to the protein of interest.

285 of proximal tubular and loop of Henle sodium handling, to assess sodium exit after loop diuretic admi

286 The method can handle unique challenges encountered during video captur

287 an 13 pg/nL HA, whereas Immolase (1 U) could handle up to 375 pg/nL HA.

288 Missing data were handled using multiple imputations.

289 ommercially available X-ray detectors can be handled using this software.

290 arameter features into the pipeline such as, handling variable-length read data, and searching splice

291 notypes, varieties and genes are improved to handle various constraints.

292 Support for training material production and handling was provided by studying the dynamic headspace

293 guidewires was rated on a four-point scale, handling was rated on a three-point scale, and catheteri

294 g a non-canonical amino acid with a chemical handle, we selectively label neuronal or glial proteomes

295 Food intake, body weight and glucose handling were assessed, together with other relevant par

296 contractility and macula densa cell calcium handling were observed.

297 =)SF2 , in turn, offer two further SuFExable handles, which can be sequentially exchanged to create 3

298 eater AQP2 abundance and altered renal water handling, with decreased water intake and urine volume,

299 c solvent-based clearing reagent that can be handled without specific safety measures.

300 Services need this information to adequately handle workplace adjustments.