ライフサイエンスコーパス: embryo

1 t and alter correct development in the early embryo.

2 proneural cell fate in the early Drosophila embryo.

3 he foregut and heart tube in the early chick embryo.

4 s regulate the onset of transcription in the embryo.

5 uring convergent extension in the Drosophila embryo.

6 where the abdomen and germ cells form in the embryo.

7 ity coordinating this crucial process in the embryo.

8 ome and the PSR chromosome in the fertilized embryo.

9 irless [Su(H)], in patterning the Drosophila embryo.

10 sues coordinate their movements to shape the embryo.

11 lead to altered vascular organization in the embryo.

12 enigmatic the role of this gene in the human embryo.

13 ntrast to WOX2 expression in the Arabidopsis embryo.

14 the blastomere stage of the preimplantation embryo.

15 s differentiate into white adipocytes in the embryo.

16 ation of Torso at the ends of the Drosophila embryo.

17 ly symmetric disc to a bilaterally symmetric embryo.

18 g cell sizes during early development of the embryo.

19 the complex events that help build the human embryo.

20 ponse to apoptotic pathway activation in the embryo.

21 ive paternal genome to generate a totipotent embryo.

22 enantioselectivity of fipronil to zebrafish embryos.

23 ions for spindle assembly in preimplantation embryos.

24 nesis is markedly similar to that of natural embryos.

25 green fluorescent protein (GFP) into diploid embryos.

26 ly decreased in nasal processes of Mllt10-KO embryos.

27 g individual cells in live analysis of mouse embryos.

28 rtilisation sampling individual and pools of embryos.

29 otic status of bovine preimplantation cloned embryos.

30 rences between in vivo and in vitro produced embryos.

31 y important beta-cell gene, Igf2 in whole F1 embryos.

32 lineages in peri- and postimplantation mouse embryos.

33 ne in sphk2(MZ) embryos compared to wildtype embryos.

34 delayed paternal genome activation in plant embryos.

35 echanism underlying the thermal tolerance of embryos.

36 injection into the cardiac crescent of mouse embryos.

37 er activity by injection into Xenopus laevis embryos.

38 of wild-type and Fgf receptor (Fgfr) mutant embryos.

39 induce LHX3(+)/LHX4(+) RP identity in mouse embryos.

40 fissure were substantially rescued in these embryos.

41 s gene is essential for development of mouse embryos.

42 condary palate development in Pax9-deficient embryos.

43 th stage VI oocytes and ending with two-cell embryos.

44 raft and adopt a metastatic program in chick embryos.

45 cently tagged BMP2b and Chordin in zebrafish embryos.

46 metaphase II (MII) oocytes and zygote stage embryos.

47 imited contribution to post-implantation pig embryos.

48 gle dorsal and ventral cells in 8-to-32-cell embryos.

49 andscape in X. tropicalis x X. laevis hybrid embryos.

50 ormed transcriptome profiling on whole mouse embryos.

51 s are derepressed and recruit p300 in hybrid embryos.

52 ular molar tooth morphogenesis in Inhba(-/-) embryos.

53 e developing palatal mesenchyme in Osr2(-/-) embryos.

54 tentially due to iron overload in developing embryos.

55 atches that rapidly disassemble in wild-type embryos.

56 specifically in nasal processes of Mllt10-KO embryos.

57 alpha is required for oviductal transport of embryos.

58 Embryos (1-4 cell stage) were microinjected with either

59 severely impaired tTreg cell development in embryos, adults, and Rag2(-/-) gammac(-/-) hematopoietic

60 ts may have evolved to restore the growth of embryos after the accumulation of DNA damage in seeds.

61 The sphk2(MZ) embryos also have strikingly increased levels of materna

62 In zebrafish embryos, an induced loss of function in snap29, aifm3, a

63 ve fascicles in the tongue of the developing embryo and demonstrates a similar stereotyped branching

64 mate ESCs correspond to the postimplantation embryo and fail to resume development in chimaeric assay

65 s of sildenafil on the fetus using the chick embryo and hypothesised that sildenafil also protects fe

66 However, in the embryo and in defined culture environments the propertie

67 cover the ventral surface of the Drosophila embryo and larva and provide templates for cuticular str

68 and triacylglycerols was observed within the embryo and radicle, showing correlation with the heterog

69 allenging due to the small size of the mouse embryo and rapid heart rate.

70 development of two zygotic compartments, the embryo and the endosperm.

71 terior-posterior axis formation of the mouse embryo and was shown to promote posterior neuroectoderma

72 ads to HB-EGF and COX-2 down-regulation near embryos and attenuates decidual reactions.

73 MP activity gradient in wild-type and mutant embryos and combined these data with a mathematical mode

74 lation of imprinted genes in Naa10p-knockout embryos and embryonic stem cells.

75 blate the OCT4 gene in human preimplantation embryos and found key differences from its function in m

76 to direct cardiac mesoderm formation in frog embryos and human embryonic stem cells.

77 expression is increased in Tgif1; Tgif2-null embryos and in double-null mouse embryo fibroblasts (MEF

78 ulated by specific mathematical equations in embryos and larvae and that accurate denticle spacing re

79 ll length over a wide range of cell sizes in embryos and larvae.

80 in high-speed image data from in utero mouse embryos and multi-angle, vector-flow algorithms were app

81 3.5 Osr2(RFP/+) and Osr2(RFP/-) mutant mouse embryos and performed whole transcriptome RNA sequencing

82 single cells from Etv2-EYFP transgenic mouse embryos and reveal specific molecular pathways that dire

83 nces to deliver BE3 RNPs into both zebrafish embryos and the inner ear of live mice to achieve specif

84 4 and Vg1 are first expressed throughout the embryo, and then become localised to the future anterior

85 rolling X chromosome activity in early human embryos, and they highlight the contribution of rapidly

86 female and male partners are both infected, embryos are viable.

87 imprinting has been reported in the chicken embryo as a whole, we interrogated the existence or abse

88 bryo sheath that forms on the surface of the embryo as it starts to elongate.

89 a rapid reduction (90%) of this drug in the embryo at hatch.

90 show that de novo polarisation of the mouse embryo at the 8-cell stage is directed by Phospholipase

91 sequences could be revealed, indicating that embryos at different development stages have their own t

92 pressing cells in the urinary tract of mouse embryos at E10.5 and distributed in the bladder at E15.5

93 from PGCCs were indistinguishable from human embryos at the blastomere, polyploid blastomere, compact

94 mly migrating in the midline region of human embryos before initiation of the CXCL12/SDF1-guided chem

95 ow cells self-organize and assemble, how the embryo breaks symmetry, and what controls timing and siz

96 Neural crest cells migrate throughout the embryo, but how cells move in a directed and collective

97 ryos have fewer primary cilia than wild-type embryos, but the cilia that form are of normal length an

98 es and hepatitis in late organogenesis mouse embryos, but the molecular and cellular mechanisms under

99 brain angiogenesis and BBB function in mouse embryos, but the role of this receptor in adult animals

100 cifies neuronal identities in the Drosophila embryo by regulating developmental patterning genes such

101 e correction of heritable mutations in human embryos by complementing preimplantation genetic diagnos

102 rm progenitors (NMPs) ensure axial growth of embryos by contributing both to the spinal cord and meso

103 ancy can cause neural tube defects (NTDs) in embryos by perturbing protein activity, causing cellular

104 ted in different tumor xenografts in a chick embryo CAM model.

105 one, and because fatty acids provided to the embryo can be manipulated through the hen diet.

106 In more severe cases, the embryo can be pushed out from the micropylar end, result

107 that chromatin compaction in preimplantation embryos can partially proceed in the absence of zygotic

108 duced HepG2 tumor growth in a modified chick embryo chorioallantoic membrane (CAM) assay, associated

109 se aortic rings and neoangiogenesis in chick embryo chorioallantoic membrane.

110 Here, using the chick embryo close to hatching, a well-accepted model for diox

111 th formed by accretion of Moon- to Mars-size embryos coming from various heliocentric distances.

112 d expression of a reporter gene in sphk2(MZ) embryos compared to wildtype embryos.

113 elevance today in light of advances in human embryo culture and in the derivation of embryonic-like s

114 Removal of Ythdf2 in zebrafish embryos decelerates the decay of m(6)A-modified maternal

115 The maternal-mediated embryo defects are associated with changes in auxin acti

116 r neuroblasts in the Drosophila melanogaster embryo delaminate as single cells from the embryonic epi

117 Exposure of zebrafish embryos demonstrated negligible effects of pregnanediol

118 an in vivo overexpression assay in zebrafish embryos demonstrating that the HP1 interaction is essent

119 migrating cells in the developing zebrafish embryo, demonstrating the utility of this system in the

120 How religions view the human embryo depends on beliefs about ensoulment and the incep

121 predictions for how the thermal tolerance of embryos depends on egg size and flow velocity of the sur

122 We observe both embryo-derived and monocyte-derived tissue-resident macr

123 tewater and river water composition affected embryo development and led to the alteration of steroido

124 y a minor role in the initial steps of early embryo development in maize.

125 from heterozygous parents were defective in embryo development.

126 or (AP) axis is a crucial step during animal embryo development.

127 ytokinesis was delayed or failed, and 50% of embryos died during development.

128 into the developing liver, and Gata4-mutant embryos died from subsequent liver hypoplasia and anemia

129 In addition, jagn-deficient embryos display defects in apical-basal spindle orientat

130 ntrast, Chn1KO/KO mice did not have DRS, and embryos displayed abducens nerve wandering distinct from

131 Morphant embryos displayed cardiac abnormalities, including peric

132 nregulation of INPP5K orthologs in zebrafish embryos disrupted muscle fiber morphology and resulted i

133 ovel numerical approach to compute the whole-embryo dynamics of the actomyosin-rich apical epithelial

134 tissues after intraspinal injection of mouse embryos (E16).

135 In light of recent human embryo editing developments, scientists and stakeholders

136 neuromesodermal progenitors (NMPs) that fuel embryo elongation by generating spinal cord and trunk me

137 and regulation during Caenorhabditis elegans embryo elongation, a process driven by asymmetric epider

138 rgans can withstand the mechanical stress of embryo elongation; mistiming of epithelium formation lea

139 formation of a normal embryo sheath and for embryo-endosperm separation.

140 The method also works well for staining embryos, even late-stage embryos with cuticles, allowing

141 Furthermore, whereas Pax9(del/del) embryos exhibit defects in palatal shelf elevation/reori

142 Here we show that Crkl mutant embryos exhibit gene dosage-dependent growth restriction

143 Pax9(del/del);Wise(-/-) double-mutant mouse embryos exhibit rescued palatal shelf elevation/reorient

144 In addition, Arhgap29(K326X/+) embryos exhibited a significantly higher percentage of m

145 and heart, the placental labyrinths of these embryos exhibited aberrant alignment of endothelial cell

146 Here we demonstrate that Drosophila embryos expressing catalytically deficient Trr eclose an

147 gh-resolution 4D imaging of transgenic quail embryos expressing fluorescent proteins.

148 These embryos fail to initiate timely MZT, undergo cell-cycle

149 that disruption of Cul9-p53 binding in mouse embryo fibroblasts (MEFs) by a knock-in mutation in Cul9

150 Tgif2-null embryos and in double-null mouse embryo fibroblasts (MEFs).

151 Here, we show that Rev1-deficiency in mouse embryo fibroblasts or mouse liver tissue is associated w

152 Embryos from Arhgap29(K326X/+) intercrosses were harvest

153 l imaging approach to analyze Cyclin B1-null embryos from fertilization onward.

154 Additionally, embryos from heat-stressed mothers displayed increased s

155 In contrast, no effect of embryo genotype was seen in concepti from heterozygous d

156 In the mouse embryo, global epigenetic changes occur during zygotic g

157 Although the DNA methylome of early human embryos has been analyzed (4-6) , some of the key featur

158 f sox9b expression in TCDD-exposed zebrafish embryos has been shown to contribute to heart and jaw ma

159 rile due to arrested gonadogenesis following embryo hatching.

160 Heterozygous or homozygous mpk6 embryos have defects only in mpk6 homozygous maternal pl

161 A methylation analyses showed that Natur-IVF embryos have expression and methylation patterns closer

162 Rsg1 mutant embryos have fewer primary cilia than wild-type embryos,

163 al in the endosperm and signaling within the embryo, highlighting the complex molecular interaction b

164 nfluences the development of next-generation embryos; however, little is known about the signaling co

165 direct the spatial patterning of developing embryos; however, the mechanisms by which these gradient

166 lymphatic endothelial cells in a vertebrate embryo identifies cells with unique features, including

167 Embryo implantation remains a significant challenge for

168 Embryo implantation requires a hospitable uterine enviro

169 he extent of functional redundancy following embryo implantation.

170 studied neuronal development in the Xenopus embryo in the absence of n1-src, while preserving c-src

171 y inhibits neural crest migration in Xenopus embryos in a Snail1-dependent manner, indicating that th

172 into the tooth bud mesenchyme in Inhba(-/-) embryos in comparison with wild-type littermates.

173 We reared lizard embryos in the laboratory under temperature cycles that

174 ity was also evident in human ESCs and mouse embryos in vivo.

175 egation in neural stem cells in vitro and in embryos in vivo.

176 he time of gastrulation in higher vertebrate embryos, inductive interactions direct cells to form cen

177 oordinately contract to expel the fertilized embryo into the uterus.

178 nt sex determination, in which the sex of an embryo is determined by the incubation temperature of th

179 ablishment of cell polarity in the mammalian embryo is fundamental for the first cell fate decision t

180 ver its downstream network in the developing embryo is not fully characterized.

181 The ectoderm of the Xenopus embryo is permeated by a network of channels that appear

182 elopmental toxicity of BMAA in the zebrafish embryo is presented in relation to the potential contrib

183 water uptake, during which metabolism of the embryo is restarted, remain enigmatic.

184 cleft palate pathogenesis in Pax9-deficient embryos is accompanied by significantly reduced expressi

185 that elimination of Wolffian ducts in female embryos is actively promoted by COUP-TFII, which suppres

186 s along the anterior-posterior axis of mouse embryos is responsible for left-right symmetry breaking.

187 of bilateral symmetry in mammalian and avian embryos is the appearance of the primitive streak in the

188 otic transition, from a fertilized egg to an embryo, is central to animal and plant reproduction.

189 Here, we discovered that female mouse embryos lacking Coup-tfII (chicken ovalbumin upstream pr

190 Murine embryos lacking EPH receptor A4 (Epha4KO/KO), which is u

191 cilia positioning that is essential to mouse embryo left-right asymmetry establishment.

192 pex1-3 conferred embryo lethality when homozygous, confirming that PEX1,

193 By contrast, Pou5f1-null mouse embryos maintained the expression of orthologous genes,

194 shortened development time without costs to embryo mass or metabolism.

195 In the developing embryo, melanoblasts originating from the neural crest m

196 Embryo morphogenesis relies on highly coordinated moveme

197 s the actomyosin contractile machinery drive embryo morphogenesis.

198 een tissue behaviors during early vertebrate embryo morphogenetic events.

199 eduction in fertility, with a mean number of embryos/mouse of 4.4 +/- 1.3 compared to 7.8 +/- 0.5 for

200 o the levels of the WT controls (9.1 +/- 0.4 embryos/mouse) (P < 0.05).

201 the wild-type (WT) C57BL/6 mice (4.3 +/- 1.4 embryos/mouse) compared to the levels of the WT controls

202 xperiences mechanical loading resulting from embryo movement.

203 ul development, cells of the early mammalian embryo must differentiate to either trophectoderm (TE) o

204 tipulates that experiments with intact human embryos must not allow them to develop beyond 14 days or

205 to read the sex chromosome karyotype, early embryos must remain gender-naive; our findings show that

206 expansion of a massive endosperm, where all embryo-nourishing reserves are ultimately stored.

207 y in the lateral line of Danio rerio and the embryo of Caenorhabditis elegans.

208 sing a split half-sibling design, we exposed embryos of 10 families from each of two populations to v

209 We find that beetle oocytes and embryos of all stages are abundant in heterogeneous 28

210 hippocampal and cortical neurons from rodent embryos of both sexes is distributed throughout the soma

211 In the embryos of diabetic mice, OGT is highly activated in ass

212 ntrations, is significantly downregulated in embryos of diabetic mice.

213 a quiescence program initiated by either the embryo or the surrounding endosperm tissues.

214 size of the larvae, compared with 2-3 d for embryos or dissected tissue stains-but time is saved by

215 alities are remarkably common in early human embryos, our understanding of early embryonic somatic mu

216 nduction of cellular senescence in zebrafish embryos overexpressing mutant, but not wild-type, PDGFRA

217 2b (Cers2b), and loss of Cers2b in sphk2(MZ) embryos phenocopies sphingosine toxicity.

218 s showed a wrinkled seed coat or a burst-out embryo phenotype.

219 olution of tetrads and rosettes in the mouse embryo, possibly in part by spatially restricting atypic

220 Eif4a3 haploinsufficient embryos presented altered mandibular process fusion and

221 In disc1 mutant embryos, proliferating rx3+ hypothalamic progenitors are

222 Mice lacking Erf in the embryo proper exhibited severe anemia and died around em

223 hich is essential for the development of the embryo proper.

224 to the onset of their expression within the embryo proper.

225 characterisation of the C. elegans wild-type embryo proteome and phosphoproteome and can be explored

226 Tissues from E17.5 embryos, pups and dams were collected for choline/methyl

227 DA clusters are primary neurons born in the embryo, rather than secondary neurons.

228 discontinuity in the dorsal epidermis of the embryo, requires both cell-cell and cell-ECM adhesions.

229 The "14-day rule" for embryo research stipulates that experiments with intact

230 n accordance, knocking down GATA3 in primate embryos resulted in a failure to form trophectoderm.

231 from pollen with two sex cells in the female embryo sac.

232 he successful delivery of sperm cells to the embryo sac.

233 development, including nonviable pollen and embryo sacs with unfused polar nuclei.

234 e micropylar end, resulting in the burst-out embryo seed phenotype.

235 stricted to artemisinin exposures during the embryo sensitive period (6-12 wk gestation) were as foll

236 es to examine effects on blood, placenta and embryo serotonin levels and neurodevelopment at embryoni

237 used different combinations of maternal and embryo SERT Ala56 genotypes to examine effects on blood,

238 necessary both for the formation of a normal embryo sheath and for embryo-endosperm separation.

239 , we describe a structure we refer to as the embryo sheath that forms on the surface of the embryo as

240 ults showed that miR-449b expression in SCNT embryos significantly enhanced the cleavage rate at 48 h

241 nsically disordered phosphoprotein, in chick embryo skeletal development, and using circular dichrois

242 While an embryo-specific promoter is ideal it may not be essentia

243 Newly fertilized embryos spend the first few days within the oviduct and

244 imordial germ cells (PGCs) of the sea urchin embryo (Strongylocentrotus purpuratus) is quiescent.

245 to DNA with a rapid off rate throughout the embryo such that its average occupancy at target loci is

246 ation similar to the posterior region of the embryo, suggesting that they develop an AP axis.

247 on of PRC1-Br140 "bivalent complexes" in fly embryos supports and extends the bivalency model posited

248 O2 are required for sheath deposition at the embryo surface but not for production of sheath material

249 en coat protein B-class) that are related to embryo surrounding factor (ESF1) developmental regulator

250 ing and pace of cell fate specification, the embryo temporally modulates plasticity and creates a tim

251 EPC cultures issued from embryos that expressed only wild-type Zeb2 (Zeb2(+/+) EP

252 analyzed a similar phenotype in POMT mutant embryos that shows left-handed body torsion.

253 m E18 transgenic mouse model or from rat E18 embryos that were transiently transfected with ASYN-GFP

254 s elicited by nucleases in cells, tissues or embryos through analysis of fluorophore-labeled PCR ampl

255 in the anterior pole of the early Drosophila embryo to explore how cells compete for space under geom

256 the mir-35 family microRNAs act in the early embryo to function as a developmental timer that preserv

257 of early divergent angiosperm lineages, the embryo to seed ratio (E : S) falls squarely within the n

258 Exposure of Xenopus embryos to AChE-inhibiting chemicals results in severe d

259 Here, we use Xenopus laevis embryos to analyze the spatial and temporal transcriptom

260 croscopy and tomography of staged C. elegans embryos to demonstrate that BBs remodel to support cilio

261 nteroposterior (AP) patterning in developing embryos, tornaria larvae, and post-metamorphic juveniles

262 lt in abnormal muscle contractions and cause embryo torsion.

263 Mammalian embryos transiently exhibit aerobic glycolysis (Warburg

264 a stage-specific manner during the oocyte-to-embryo transition by activating transcription, altering

265 novo biogenesis of MVEs during the oocyte-to-embryo transition in C. elegans.

266 and ensures irreversibility of the oocyte-to-embryo transition.

267 Its small size, high proliferative rate, embryo transparency and small amount of drug required ma

268 frequently in the anterior pole than in the embryo trunk.

269 The vertebrate embryo undergoes a series of dramatic morphological chan

270 f de novo transcription in living Drosophila embryos using dual-fluorescence detection of nascent tra

271 cular development was validated in zebrafish embryos using morpholino oligonucleotides.

272 quantification of single mRNAs in Drosophila embryos, using commercially available smFISH probes (e.g

273 Rbpr2) for RBP4-retinol uptake in developing embryos, using eye development and vision as sensitive r

274 efficient disabling pancreatogenesis in pig embryos via zygotic co-delivery of Cas9 mRNA and dual sg

275 tive to the central blastocoel cavity of the embryo, was found to be consistent with the observed gap

276 entral (DV) axis formation in the Drosophila embryo, we find that the poised enhancer signature is sp

277 Using the chick embryo, we uncover novel genes in the gene regulatory ne

278 and function of this CTCF-rich DNA region in embryos, we compared chromatin interaction profiles betw

279 of apical polarity proteins in Nematostella embryos, we demonstrate that cell polarity is establishe

280 ng cell lines from Hat1+/+ and Hat1-/- mouse embryos, we demonstrate that Hat1 is not required for ei

281 proaches and live-cell imaging in Drosophila embryos, we dissect the role of condensin I in the maint

282 effects of phosphomutants in Xenopus laevis embryos, we identify the novel site S267 as being an imp

283 able phenotypic plasticity in Pacific salmon embryos, we measured the developmental rate, survival, a

284 OS levels between SR-BI(+/+) and nSR-BI(-/-) embryos were detected in SR-BI(-/-) with NTD (NTD SR-BI(

285 Gulf killifish embryos were exposed to dissolved Cu and CuO NP mixtures

286 Natur-IVF embryos were of higher quality than C-IVF in terms of ce

287 quirement for microbial colonization, axenic embryos were serially colonized on 1, 3, 6, or 9 dpf and

288 -h aerobically and anaerobically germinating embryos, when there is little cell division.

289 future anterior and posterior regions of the embryo, where they will, respectively, inhibit or induce

290 depletion is lethal in preimplantation mouse embryos, where it blocks the transition from morula to b

291 ix groups of primary DA neurons (born in the embryo), which we assign to six distinct lineages.

292 ive Toll receptors are limiting in wild-type embryos, which is a key factor in explaining global Dors

293 A 3D continuum model of the embryo with induced contractility demonstrates that cont

294 Whereas SR-BI(-/-) embryos with closed neural tubes (nSR-BI(-/-)) had high

295 s well for staining embryos, even late-stage embryos with cuticles, allowing characterization from ea

296 ve formed from a heterogeneous assortment of embryos with distinct isotopic compositions.

297 ous MYBPC3 mutation in human preimplantation embryos with precise CRISPR-Cas9-based targeting accurac

298 rd to how different religions view the human embryo, with a focus on the Christian faith as well as B

299 PRC1-Br140 bind developmental genes in fly embryos, with analogous co-occupancy of PRC1 and a Br140

300 Here we report that zebrafish embryos without maternally provided vg1 fail to form end