ライフサイエンスコーパス: defense

1 ing pathway is involved in CP-mediated plant defense .

2 on of host proteins and protection from host defense.

3 on and compromising intestinal antimicrobial defense.

4 ed by processes implicated in plant pathogen defense.

5 eir ability to respond and facilitating host defense.

6 rganisms toward an adaptive peak of chemical defense.

7 fector cells and renews itself for continued defense.

8 involved in disease resistance and pathogen defense.

9 and olive massively releases the arsenal of defense.

10 Neutrophils play a crucial role in host defense.

11 hospitals administered by the Department of Defense.

12 or and fitness by altering plant quality and defense.

13 and failure to participate in antimicrobial defense.

14 CP14 transcription factor to manipulate host defense.

15 g ROS production, an important innate immune defense.

16 e vascular integrity while coordinating host defense.

17 new role in producing AMPs for innate immune defense.

18 ffects on ocular immune homeostasis and host defense.

19 hytohormones are central regulators of plant defense.

20 idases in the context of non-specific immune defense.

21 to understand its regulatory network in SCN defense.

22 responses, wound healing, and anti-microbial defense.

23 atalysis against microbial antigens for host defense.

24 ave been described that are also key to host defense.

25 mited resources for growth, development, and defense.

26 ted autoimmune disease but blocked antiviral defense.

27 are critical in antimicrobial and antitumor defense.

28 , including wounding, perhaps to evoke plant defense.

29 ble immunity and comprises primordial innate defense.

30 key role in grapevine (Vitis vinifera) leaf defense.

31 pparently a strong offense is the eel's best defense.

32 ation of signaling favoring either growth or defense.

33 g them important components of body's immune defense.

34 individuals with partially compromised piRNA defense.

35 ritical role for NK cells in human antiviral defense.

36 Cs) play critical roles in developing immune defenses.

37 with likely roles in protection against host defenses.

38 re's ability to manipulate JA-mediated plant defenses.

39 gRNA is likely important for countering host defenses.

40 the suppressive function of NaJAZi on floral defenses.

41 ulation of genes involved in GAS antioxidant defenses.

42 cesses including brain development and plant defenses.

43 o optimize infection and counter host immune defenses.

44 es are protected by jasmonate (JA)-inducible defenses.

45 conserved role in balancing plant growth and defenses.

46 ly in constitutive but also in induced plant defenses.

47 he ability of a virus to counteract the host defenses.

48 dependence on atypical intrinsic and innate defenses.

49 ol and whether this access triggers cellular defenses.

50 ga species was correlated with similarity in defenses.

51 pathogens from immune surveillance and host defenses.

52 lentless selective pressure from host immune defenses.

53 tate viral replication and inhibit antiviral defenses.

54 cules in preformed and inducible Arabidopsis defense, a role previously dominated by tryptophan-deriv

55 ivity, but the participation of PTEN in host defense against bacterial infection is less well underst

56 studies reveal a novel role of mast cells in defense against bacterial infections.

57 as systems provide prokaryotes with adaptive defense against bacteriophage infections.

58 with respect to growth and morphogenesis and defense against biotic and abiotic stress.

59 In contrast, TLR7 was important for defense against disease in the lungs.

60 an essential role of Rif1 in the epigenetic defense against ERV activation.

61 Astrocytes are a primary defense against hyperexcitability, but their functional

62 T cells provide immune-surveillance and host defense against infection and cancer.

63 ce suggests they have multiple roles in host defense against infection.

64 Collectively, PTI contributes to host defense against infections by a broad range of pathogens

65 iary beating, is the primary physical airway defense against inhaled pathogens and irritants.

66 ly activated" phenotype that participates in defense against intracellular pathogens.

67 gated the role of plant toxins in nectar for defense against nectar robbers [4, 9, 10].

68 g cassette (ABC) transporter plays a role in defense against numerous pathogens and is recruited to s

69 bility to store H2S in vivo and as a line of defense against oxidative stress, from which it is clear

70 ffects of the propolis envelope as a natural defense against Paenibacillus larvae, the causative agen

71 stinal mucous layer provides a critical host defense against pathogen exposure and epithelial injury,

72 Skin provides the first defense against pathogenic micro-organisms and is also c

73 of our digestive tract is the first line of defense against pathogens and damage.

74 n the control of cell-signaling pathways and defense against pathogens and whose imbalance leads to p

75 masome activation is critical for the host's defense against pathogens, but dysregulation of inflamma

76 ntibodies provide an efficient first-line of defense against pathogens.

77 une systems in animals and plants as natural defense against pathogens.

78 microbial peptides (AMPs) as a first line of defense against pathogens.

79 ivo Macrophages are a critical first line of defense against respiratory pathogens.

80 ypothesis that platelets participate in host defense against S. aureus both through direct killing of

81 matory monocytes (iMO) are critical for host defense against toxoplasmosis and malaria but their role

82 ired for selective autophagy of Mtb and host defense against tuberculosis infection.

83 nd topically applied DHA potentiate cellular defense against UVB-induced skin inflammation and photoc

84 The first line of defense against viral infections is the innate immune re

85 ons (IFNs) play a central role in the immune defense against viral infections.

86 Type I IFNs are key mediators of immune defense against viruses and bacteria.

87 , cell types known to be important for early defenses against L. monocytogenes in the spleen, as well

88 33c's activity was consistent with a role in defenses against oxidative stress generated during host

89 Mast cells (MCs) are involved in host defenses against pathogens and inflammation.

90 development and provides insights into host defenses against pathogens and the immunological mechani

91 optosis is a form of cell death important in defenses against pathogens that can also result in a pot

92 ry disease is able to promote antiviral host defenses against the influenza virus.

93 or conditionally beneficial functions (e.g., defense and development), display faster evolutionary ra

94 hormone jasmonic acid (JA) is vital in plant defense and development.

95 To compile DMH maps for the autonomic cold defense and for the cold-seeking response to LPS, we stu

96 report that SDE5 is involved in basal plant defense and mRNA export.

97 a role for secretory autophagy in intestinal defense and suggest why Crohn's disease is associated wi

98 to define the genetic determinants of genome defense and to reveal the molecular and cellular mechani

99 improve insect fitness by suppressing plant defenses and detoxifying defensive phytochemicals.

100 IS treatment alters innate antimicrobial defenses and disrupts the gut microbiota, which leads to

101 ctors into host cells in order to evade host defenses and establish infection.

102 lar proteins allows viruses to suppress host defenses and generate infectious progeny.

103 Neutrophils play a key role in host defenses and have recently been implicated in the pathog

104 hat involve microbe-induced changes to plant defenses and nutritive quality as well as the consequenc

105 ithelial cells, evading immune and antiviral defenses and provide an explanation for the incidence of

106 nt fitness due to herbivore-induced chemical defenses and signaling on pollinators (herbivore-induced

107 usly, PmtA was implicated in GAS antioxidant defenses and suggested to protect against zinc toxicity.

108 he expression of genes involved in immunity, defense, and development.

109 mportant role in cellular energetics, stress defense, and neoplastic transformation.

110 late development, growth, metabolism, immune defense, and reproduction in response to internal and ex

111 hich hepcidin and hypoferremia modulate host defense, and the spectrum of microbes affected, are poor

112 y to play important roles in subverting host defenses, and constitute a valuable pool of anti-inflamm

113 ation, but their relative roles in antiviral defense are not well understood.

114 our results indicate that amphibian chemical defenses are not fixed.

115 f the atopic response, participate in immune defense at host/environment interfaces, yet the mechanis

116 its single-cell stage and for antibacterial defense at its multicellular stages.

117 t these compartments to overcome the plant's defense barrier.

118 rize the mechanism(s) of honey bee antiviral defense, bees were infected with a model virus in the pr

119 flight and freezing, two different types of defense behavior, respectively.

120 s including for genes implicated in pathogen defense, biotic and abiotic stress.

121 lmonella bacteria less resistant to the host defenses both in vitro and in vivo.

122 Complement plays a key role in host defense, but its dysregulation can cause autologous tiss

123 -22 plays a critical role in mucosal barrier defense, but the mechanisms that promote IL-22 expressio

124 s evades and disrupts the first line of host defense by degrading human mucin-2 (MUC2), depleting muc

125 cyte precursor cells and contributes to host defense by mediating microbial killing.

126 of the tradeoff between growth and ER stress defense by the stress response hormone salicylic acid (S

127 d, suggesting prevention of innate antiviral defense by ZIKV.

128 cytomegalovirus (HCMV), blunt host antiviral defenses by limiting ISG expression, the overall abundan

129 ves production of these structurally related defense collagens, SP-A and C1q, and the expression of t

130 c engineering to produce components of these defense compounds in a heterologous host.

131 irus X protein (HBx) as a suppressor of host defenses consisting of RNAi-based silencing of viral gen

132 cussive blast injuries met the Department of Defense definition of mild, uncomplicated TBI.

133 immune cytokine production and antibacterial defense, demonstrating a novel role for RIPK1 kinase-ind

134 esponse to VSV plays a key role in antiviral defense during infection.

135 mune effector mechanisms to promote the host defense during influenza virus infection.

136 VI, but not CLEC2, contributes to local host defense during pneumonia-derived sepsis by enhancing leu

137 helial cell proliferation and antiviral host defense during the normal wound healing response.

138 Thus, the temporal transition of host defense from innate to adaptive immunity is unexpectedly

139 tion and the downstream responses separating defense from symbiosis in the roots of the 80-90% of lan

140 esicles in phagocytic uptake, the key innate defense function.

141 tation of cell wall, hormone metabolism, and defense gene categories.

142 or flg22-induced defense responses including defense gene expression, callose deposition, and reactiv

143 ormone salicylic acid (SA) and activation of defense gene expression.

144 ccumulation of salicylic acid (SA)-inducible defense genes (ZmNAC, ZmHSF, ZmWRKY, ZmbZIP and PR1) and

145 plicated in expression of autophagy and host defense genes in nematodes and mammalian cells.

146 (NFE2-related factor2) triggers antioxidant defense genes to defends against homeostatic failure.

147 ion as transcriptional coactivators of plant defense genes.

148 This unique defense has reportedly been used against both horses [7]

149 ociated bacteria in regulating plant induced defenses has not been adequately examined.

150 y, death-independent roles for RIPK3 in host defense have not been demonstrated.

151 ect gut-associated microbes modulating plant defenses have been observed in beetles and piercing-suck

152 signaling modulators involved in host immune defense, have not been fully elucidated.

153 at TOR antagonizes the action of the classic defense hormones salicylic acid and jasmonic acid.

154 hus, whereas diabetes influences host immune defense, hyperglycemia itself does not cause generalized

155 recognition and pathogen infection, induced defense (immunity), and the deterrence of insect pests.

156 e that CRISPR2 can be reactivated for genome defense in MDR strains.

157 glands, which are potent organs for chemical defense in most oribatid mites.

158 OG1, in guard cell signaling and early plant defense in response to bacterial pathogens.

159 efore constitute the front line of antiviral defense in the lung without compromising host fitness.

160 We review the mechanisms underlying host defense in the very young, and discuss how specific deve

161 ork for histone release and function in host defense in vivo was revealed with the discovery of neutr

162 Here, we examined suppression of JA-mediated defense in wild and cultivated hosts of CPB by chemical

163 cues.Plants are able to prime anti-herbivore defenses in response to olfactory cues of insect pests.

164 To better understand belowground defenses in the field, we performed root metabolomic pro

165 contribution of phagocytosis and other host defenses in the research for, and the design of, antibio

166 CPB larvae suppressed jasmonate (JA)-induced defenses in tomato.

167 y be involved in the manipulation of induced defenses in wild and cultivated Solanum plants of CPB.

168 transcription factor MYB15 as a regulator of defense-induced lignification and basal immunity.

169 any time point of infection with virulent or defense-inducing DC3000 strains.

170 How self-defense is suppressed remains elusive.

171 However, the ability of SCVs to resist host defenses is largely uncharacterized.

172 olved in immune regulation and antimicrobial defense, is a target for these proteases and that proteo

173 rocytosis, is considered beneficial for host defense, little is known about Mtb-infected necrotic neu

174 RNA silencing pathway are involved in plant defense machinery against microbial pathogens in Arabido

175 a conserved, essential function, yet genome defense machinery evolves rapidly.

176 activity that is important in antimicrobial defense, MAIT cells have immune-modulatory functions tha

177 ell-based mechanism of immune exclusion is a defense mechanism against pathogens that complements the

178 ts are removed from the nucleus by CRM1 as a defense mechanism against proteotoxicity of misfolded SO

179 ree plant families, probably as an elemental defense mechanism and perhaps mediating elemental allelo

180 marked and antagonized by a universal immune defense mechanism targeting diverse pathogens replicatin

181 c oxide (NO) in myeloid cells that acts as a defense mechanism to suppress invading microorganisms or

182 Apoptosis is an important antiviral host defense mechanism.

183 g to evasion of this important innate immune defense mechanism.

184 , programmed cell death can also represent a defense mechanism; for example, by depriving pathogens o

185 However, it is not known what types of defense mechanisms a plant would already possess to defe

186 Not much is known about defense mechanisms against C. albicans in subepithelial

187 n about how histone methylation may regulate defense mechanisms and flowering time in plants.

188 ustrate their action mechanisms, focusing on defense mechanisms in the GI tract.

189 Upon bacterial infection, one of the defense mechanisms of the host is the withdrawal of esse

190 ese data provide important insights into the defense mechanisms used by syncytiotrophoblasts at vario

191 es play a pivotal role in intrinsic immunity defense mechanisms, often deleteriously mutating invadin

192 onas, with specific upregulation of membrane defense mechanisms.

193 flexibility of HIV-1 in counteracting human defense mechanisms.

194 ost cell signaling pathways and subvert host defense mechanisms.

195 protein and provide insights into antiviral defense mechanisms.

196 To identify mechanisms of defense metabolite signaling, we used glucosinolates, an

197 little understanding of mechanisms enabling defense metabolite signaling.

198 y compromised in herbivore-induced levels of defense metabolites such as nicotine, phenolamides, and

199 glucosinolates, an important class of plant defense metabolites.

200 viral replication by the host innate immune defense might contribute to this phenomenon.

201 The Department of Defense Military Health System Data Repository was queri

202 In addition to their function in plant defense, monoterpenes are also used as flavors, fragranc

203 laboratory-reared larvae maintained chemical defenses nearly three-fold greater than those of sibling

204 Gervais & Fessler's defense of a sentiment construct for contempt captures f

205 addition, the model fundamentally breaks the defense of modern text-based CAPTCHAs (Completely Automa

206 Chemical defense of nectar is, however, ultimately constrained by

207 nal, heme-dependent enzyme in the front-line defense of numerous bacterial and fungal pathogens again

208 inflammation and contributes to mucosal host defense of the nasopharyngeal niche, a reservoir for ME

209 Finally, we compared the phylogeny and defenses of Inga to phylogenies for the major lepidopter

210 hetes that succeed in overcoming the natural defenses of the ocular conjunctiva and transit through t

211 cantly impact the processes of host-pathogen defense, organ rejection, and wound healing.

212 ll plays an important role in communication, defense, organization and support.

213 ys, including social signaling, antipredator defenses, parasitic exploitation, thermoregulation, and

214 Rather than compromising host defenses, pathogen-mediated inhibition of anorexia incre

215 tions between the salicylic acid (SA) and JA defense pathways, efforts to increase resistance to biot

216 utive activation of salicyclic acid-mediated defense pathways.

217 ses such as central metabolism and oxidative defense pathways.

218 ween these functionally interconnected basal defense pathways.

219 n of epithelium- and neutrophil-derived host defense peptides (HDPs) (LL-37 and human beta-defensin-3

220 We studied host defense peptides from the skin of the South Indian frog

221 Despite enhanced sensitivity to host defense peptides, the Y. pseudotuberculosis DeltarfaH st

222 ssociated with resistance to endogenous host-defense peptides.

223 an open question whether amphibian chemical defense phenotypes are inducible.

224 the perceptual capabilities underlying plant defense priming in response to olfactory cues.Plants are

225 Inflammation is a host defense process against infection.

226 overall transcriptomic control of the plant defense processes occurring during herbivory.

227 s aeruginosa adhesion if it lacks the innate defense protein MyD88 (myeloid differentiation primary r

228 0 congeners that interfere with the cellular defense protein P-glycoprotein, termed transporter inter

229 Our results indicate that PEN3 and other defense proteins continuously cycle through the TGN and

230 The delivery of several host defense proteins to PVs is controlled by IFN-inducible g

231 deposition, and the synthesis of structural defense proteins, proposed as CW-remodeling mechanisms e

232 related herbivores fed on Inga with similar defenses rather than on closely related plants.

233 nd pathophysiological processes such as host defense, regulation of gene expression, cellular homeost

234 g against pathogens, XBAT35.2 interacts with defense-related Accelerated Cell Death11 (ACD11) in plan

235 8 treatment confirms increased expression of defense-related genes compared with the wild type.

236 or co-regulation modes of enhancers and find defense-related genes often simultaneously regulated by

237 Lineage-specific expression of defense-related genes was characterized through comparis

238 2K1-associated coexpression network contains defense-related genes, including those encoding jasmonat

239 f GmADA2/GmGCN5 resulted in misregulation of defense-related genes, most likely due to decreased H3K9

240 and transcription, but also suppresses many defense-related genes.

241 , associated with elevated concentrations of defense-related hormones.

242 which could imply a role in the synthesis of defense-related lignin.

243 ding valuable insight into the mechanisms of defense-related responses in plants.

244 ate stomatal aperture for pathogen entry and defense, respectively.

245 ganelles and the cytoskeleton to the plant's defense response against microbial pathogens, as well as

246 VY) in potato genotypes that differ in their defense response against the virus.

247 At the same time points, several defense response genes (encoding LRR-containing, NBARC-c

248 e show that K6a network remodeling is a host defense response that directly up-regulates production o

249 enes involved in hormone signaling pathways, defense response, glucosinolate biosynthesis, cell wall

250 ltered and enriched for proteins involved in defense response, wound healing and protein phosphorylat

251 amming critical to mount an appropriate host defense response.

252 hosphorous supply and salicylic acid-related defense response.

253 d, further metabolized, and contributes to a defense response.

254 posure to stress (UV, heat) or by hosts as a defense response.

255 ve oxygen species responses and induction of defense-response genes in roots.

256 re-programming substantially overlapped with defense responses against insects and fungal pathogens i

257 The AtZAR1 NLR induces strong defense responses against P. syringae and X. campestris

258 Plant defense responses at stomata and apoplast are the most i

259 ibit Xcc-, Psp NPS3121- and/or flg22-induced defense responses including defense gene expression, cal

260 RNA is transferable and its role in systemic defense responses remain unknown.

261 Pathogen effectors can inhibit defense responses, alter host physiology, and represent

262 s the JA signaling pathway to maximize plant defense responses.

263 can be recognized by plants to trigger plant defense responses.

264 Potential defense responsive pathways include effector endocytosis

265 r, our data point to Ccr7 as a critical host defense restriction factor limiting neuroinflammation du

266 pre-existing genomic locus, and extend piRNA defense roles to include the period when endogenous retr

267 he salicylic acid- and jasmonic acid-related defense signaling pathways.

268 through clathrin-coated vesicle trafficking, defense signaling through membrane lipid metabolism and

269 layered immune system with well-orchestrated defense strategies against pathogen attack.

270 ring development, and whether this is a host defense strategy or active recruitment by the parasites

271 ing that two independent pathways form these defense structures.

272 cantly to enhancement of retinal antioxidant defense system and preservation of histological structur

273 pose that SV treatment invigorates the plant defense system by regulating the SA-mediated priming eff

274 Thus, the cell autonomous defense system can mobilize and coalesce multiple subcel

275 Upon cell destruction, the dual-partner defense system is activated and olive massively releases

276 The complement system is a front-line defense system that opsonizes and lyses invading pathoge

277 The glyoxalase pathway is an antioxidant defense system utilized to detoxify methylglyoxal and ne

278 recruiting the thioredoxin (Trx) antioxidant defense system would prevent HAAF and normalize glucose

279 whereby mobile genetic elements capture host defense systems and repurpose them for different stages

280 The functions of these defense systems follow several distinct strategies, incl

281 Genes related with plant defense systems, hormone biosynthesis and response were

282 Similar to other defense systems, the NRF2-mediated stress response is co

283 one of the major costs of maintaining these defense systems.

284 r HIV-1 virus is far better at evading these defenses than the corresponding gene from a common HIV-1

285 human organ, and it provides a first line of defense that includes physical, chemical, and immune mec

286 tive in the germline, which, in turn, mounts defenses that restrain their activity [3, 4].

287 des an overview of mammalian antifungal host defenses that show promise for informing therapeutic and

288 anks to phagocytic leucocytes and other host defenses, the vast majority of these infections are self

289 interferon production for primary antiviral defense through cascades controlled by protein ubiquitin

290 egress as well as the avoidance of antiviral defenses through the sequestration of key cellular facto

291 es autoimmune diseases while preventing host defense to infection and promoting tumor growth and meta

292 veloping novel strategies for enhancing host defense to infections in newborns.

293 We conclude that O-AS function as direct defenses to protect plants from attack by both native pa

294 Tetrodotoxin (TTX) is a key chemical defense trait in North American and Eurasian newts (Sala

295 of secondary metabolites (SMs) critical for defense, virulence, and communication.

296 This suggests that plant defenses were active within or at the root surface.

297 ctive effect was suppressed when antioxidant defenses were restored.

298 licylic acid (SA) plays an essential role in defense, whether the master regulator of SA signaling, N

299 tients, possibly leading to a disturbed host defense, which facilitates bacterial persistence.

300 king lignin biosynthesis to plant growth and defense will help lignin engineering efforts to improve