ライフサイエンスコーパス: chase

1 injection 15 min after tracer delivery (DMI chase).

2 ministered in neonates followed by a 1-month chase.

3 determined using (35) S radiolabeling pulse chase.

4 8-OH-DPAT also increased latencies to chase.

5 all intestinal crypt cells after a four-week chase.

6 f excess unlabeled CO or methyl group in the chase.

7 idues in protein during a 24-h pulse and 4-d chase.

8 nrichment in the pulse and a decrease in the chase.

9 aches, flight loops and dives, hovering, and chases.

10 ly increased their vocalization rates during chases.

11 ptic components would be compared with pulse-chase (15)N labeling in mice and (14)C content in human

12 However, pulse-chase 5-bromodeoxyuridine-labeling assay revealed that t

13 During flight a male housefly chasing a female executes a corrective turn within 40 ms

14 ramine pretreatment, a 1.5 mg/kg desipramine chase administered 10 min after tracer injection, and sa

15 on of Persist End Atrial Fibrillation Study [CHASE-AF]; NCT01580124).

16 t are difficult for defector to discover and chase after.

17 Herein, we develop ratiometric pulse-chase amidination mass spectrometry (rPAm-MS) as a site-

18 rmine translation rates of messages by pulse-chase analyses in living Escherichia coli cells and show

19 Pulse-chase analyses reveal that active site inhibitors do not

20 Moreover, pulse-chase analyses reveal that S-palmitoylation is important

21 Pulse-chase analyses revealed that residues 9-20 of the AAP co

22 Metabolic pulse-chase analyses, small molecule inhibitor treatments, and

23 sing a combination of steady state and pulse-chase analyses, we show that FKBP38 knockdown increases

24 Furthermore, the primer-extension pulse-chase analysis affirmed that the reconstituted N. crassa

25 However, ex vivo pulse-chase analysis clearly shows that in the absence of AIPL

26 Pulse-chase analysis demonstrated that the absence of the term

27 Pulse-chase analysis indicated that in S6-expressing cells, al

28 Fluorescence pulse-chase analysis of an internally tagged Cse4 reveals that

29 macrophages (MDM) and microglia using pulse-chase analysis of fibrillar and oligomer (125)I-Abeta40

30 rthogonal clickable fluorophores, dual pulse-chase analysis of Lck revealed accelerated palmitate cyc

31 Pulse-chase analysis of PrP and APP by fluorescent gel imaging

32 Pulse-chase analysis revealed that all six nsp2 species were r

33 Pulse-chase analysis revealed that pre-termination ribosomes t

34 Pulse-chase analysis revealed that the initial particle produc

35 Pulse-chase analysis showed that the rates and amount of crypa

36 Quantitative imaging, pulse-chase analysis, and high-resolution ratiometric live-cel

37 Parabiosis, bromodoxyuridine (BrdU) pulse-chase analysis, and intranasal instillation of tracers i

38 As shown through a pulse-chase analysis, the mdVp1s were derived from the newly s

39 Using pulse-chase analysis, we characterized SMN protein turnover an

40 Using microscopy-based pulse-chase analysis, we find that Smo moves through a lateral

41 Moreover, using pulse-chase analysis, we show that this activation is maintain

42 se of global translation inhibitors during a chase and also provides a "built-in" reference protein.

43 om the cell surface of about 50% after a 4 h chase and became undetectable if clathrin-coated pit-med

44 As measured by pulse-chase and cycloheximide chase assays, a major binding si

45 Pulse-chase and cycloheximide-chase assays demonstrated that t

46 Pulse-chase and endoglycosidase H analysis demonstrate that th

47 Pulse-chase and kinetic spectral experiments and modeling esta

48 mploying histone and nucleotide double-pulse-chase and lineage tracing, we show that the early SC des

49 Pulse chase and mutational analysis indicated that HRD1 inhibi

50 the transcription of Bach1 as shown by pulse chase and real time PCR experiments.

51 sequencing (Bru-Seq) and bromouridine pulse-chase and sequencing (BruChase-Seq) to assess genome-wid

52 processing and stability by metabolic pulse-chase and surface On-Cell Western blots revealed that WT

53 We used EdU pulse-chase and tissue-reconstruction approaches to analyze ho

54 We used stable-isotope pulse-chase and total proteome mass-spectrometry to identify p

55 ion-ratchet model, where ParB on the plasmid chases and redistributes the ParA gradient on the nucleo

56 ereby overcoming the problem of significance chasing and approximate replications.

57 whale, including rorqual whales, show active chasing and feeding, i.e., skimming, suction, and engulf

58 ly recreated the observed interactions, i.e. chases, and best matched the observed spatial patterns f

59 Pulse-chase application of azidohomoalanine and homopropargylg

60 re we show, by combining two different pulse-chase approaches--genetic fate-mapping with stable isoto

61 on are specific to courtship; locomotion and chasing are common to both.

62 tion seeking is likely to manifest in thrill-chasing art that draws on the arousing interplay of posi

63 bly, after 8 weeks of labeling and a 12-week chase, as much as 44% of all granular neurons in the den

64 A pulse-chase assay of common SDHB missense mutations in transfe

65 Cycloheximide chase assay showed a decrease in the half-life of KLF8 p

66 Moreover, a pulse-chase assay showed that two chimeric precursors with the

67 stability of KLF5 as shown by cycloheximide chase assay, indicating that SMURF2 specifically destabi

68 Import time-course and chase assays confirmed that cpTatC targets to thylakoids

69 lycosylated F27C variants in metabolic pulse-chase assays coupled with flow cytometry and cell surfac

70 (3)H-uridine pulse-chase assays demonstrate that BLM expression is required

71 Pulse-chase and cycloheximide-chase assays demonstrated that the marked reduction in t

72 Cycloheximide chase assays revealed a shortening of APP half-life with

73 ng radioactive auxin to be removed for pulse chase assays that determine transport rates.

74 of immobilized 11-residue peptides and pulse-chase assays to examine the substrate specificity of mou

75 During import-chase assays using intact chloroplasts, Plsp1 was incorp

76 Pulse-chase assays with BrdU confirmed intracellular replicati

77 rmation and a lack of equilibration in pulse-chase assays) were also seen with (rat) P450 2B1, which

78 As measured by pulse-chase and cycloheximide chase assays, a major binding site Nedd4-2 mutant had a

79 By cycloheximide chase assays, we found that KLF5 decreases MKP-1 protein

80 Using [(35)S]methionine pulse-chase assays, we observed that the Isc pathway, but not

81 otein stability estimated from cycloheximide chase assays; and 3) prevent the CaValpha2delta1-mediate

82 m, focusing on later aspects of transport by chasing Au-Fc before fixation.

83 discoideum is a professional phagocyte that chases bacteria through chemotaxis and engulfs them as f

84 Chasing behavior, and the latencies to chase or quit, du

85 ated from wild-type animals induce male tail-chasing behavior, while ECVs isolated from klp-6 animals

86 e analog JHC1-64 and by reversible and pulse-chase biotinylation assays showing evidence for lysosoma

87 Indeed, pulse-chase biotinylation experiments in IECs lacking AnxA2 de

88 chemoattractant GPCR that mediates not only chasing but also ingesting bacteria.

89 When chased by the addition of cold ATP, 90% of the phosphoen

90 simultaneous, opportunistic, short-distance chasing by dogs pursuing multiple prey (rather than long

91 Neutrophils were directly seen to chase C. neoformans cells and then rapidly internalize t

92 rting (33)P-phosphate-pulsed (32)P-phosphate-chased cells, we demonstrate that both Prochlorococcus a

93 Pulse-chases combined with mutagenesis studies reveal that Ser

94 wolf" display, in which one item (the wolf) chased continuously, but its goal (i.e., the sheep) freq

95 Additionally, a desipramine chase did not change the cardiac (123)I-MIBG uptake (del

96 orted to hunt with energetically costly long chase distances.

97 'PO4-end exposed by nascent RNA cleavage and chases down the RNA polymerase.

98 , in vitro binding studies utilizing a pulse-chase electrophoretic mobility shift assay protocol reve

99 loss, we performed a bromodeoxyuridine pulse-chase experiment and found that a subset of ependymal la

100 amination of selected mutants during a pulse-chase experiment demonstrated an increase in F protein c

101 starting point for a crystallographic pulse-chase experiment of the active site during turnover.

102 We employed a carbon-13 pulse-chase experiment to investigate how a temperate estuarin

103 A pulse-chase experiment was used to demonstrate that even for t

104 Here, using a (13)C pulse-chase experiment, we demonstrate how trophic structure i

105 iphosphate (mantATP) is replaced by ATP in a chase experiment.

106 when compared with control cells in a pulse-chase experiment.

107 Using nucleoside pulse-chase experiments and clonal analysis, we determined tha

108 EdU pulse-chase experiments and in vivo tracking of individual tra

109 The study shows that (13)CO2 pulse-chase experiments are powerful in elucidating, under in

110 Lipid turnover rates were studied by pulse-chase experiments at the single cell level.

111 Pulse-chase experiments confirm that LRAD3 expression signific

112 (14)CO2 pulse-chase experiments confirmed that water deficit enhanced

113 of tumour cell proliferation with TMZ, pulse-chase experiments demonstrate a tumour re-growth cell hi

114 Pulse-chase experiments demonstrate that in cells expressing b

115 EdU pulse-chase experiments demonstrated a perivascular cancer ste

116 Western immunoblots and pulse-chase experiments demonstrated that EsaR is stable in vi

117 Pulse-chase experiments demonstrated that in the presence of t

118 Pulse-chase experiments demonstrated that the down-regulation

119 (54)Mn chase experiments demonstrated that the mutant was not a

120 BrdU pulse-chase experiments demonstrated the longevity of the DEX-

121 In organello, pulse labelling and pulse-chase experiments have enabled us to track the mitochond

122 Pulse-chase experiments identified sites of cell surface growt

123 Pulse chase experiments in 293 T cells expressing rhGAA with o

124 Pulse-chase experiments in COS-7 cells show that there is a KC

125 Pulse-chase experiments in gonococci demonstrated that LtgA pr

126 However, antibiotic chase experiments in vivo indicate that FtsZ degradation

127 elemental effect using dNTPalphaS, and pulse-chase experiments indicate that a rapid phosphodiester b

128 Pulse chase experiments indicate that the newly-generated cell

129 Inducible cell line and cycloheximide-chase experiments indicate that these drugs prevent inco

130 Pulse-chase experiments indicated decreased protein turnover i

131 hey enable regional optical marking in pulse-chase experiments on live cells and tissues, and they ar

132 occurred at 2.1 muM(-1) s(-1), and the pulse-chase experiments revealed an ATP-promoted isomerization

133 Pulse-chase experiments revealed that A774wt and avirulent rec

134 Fate mapping using BrdU pulse-chase experiments revealed that such deficits may origin

135 Furthermore, pulse-chase experiments revealed that the binding of QPD mutan

136 Biotin chase experiments revealed that the immature surface cha

137 A series of pulse-chase experiments revealed that the origin of aortic vas

138 Pulse and chase experiments show that LDAH enhances TAG biogenesis

139 ity of the aldehydes for P450 2A6, but pulse-chase experiments showed only limited exchange with adde

140 Pulse-chase experiments showed that a fraction of gO remained

141 Pulse-chase experiments showed that collagen type I secretion

142 Cycloheximide chase experiments showed that Ecm7 was stabilized by Mid

143 Long-term pulse-chase experiments showed that the mature DeltaRI/DeltaF5

144 Radioactive nucleotide chase experiments showed that the mechanism of TBSV repl

145 Here, we report genetic pulse-chase experiments that define osteoblastic cells as shor

146 ues to follow formation of NR by using pulse-chase experiments to examine protein and lipid delivery

147 n culture and bromodeoxyuridine (BrdU) pulse-chase experiments to identify and evaluate stem cell fun

148 Finally, pulse-chase experiments using [(14)C]serine revealed that Ups1

149 ocapsids into virions as determined in pulse-chase experiments was dependent on the activity of actin

150 Pulse-chase experiments with (14)CO(2) show that transport of

151 lags were observed in acid formation; pulse-chase experiments with carrier aldehydes showed only lim

152 ne binding event), consistent with data from chase experiments with catalytically inactive mutant Pol

153 Optical pulse-chase experiments with Dendra2-tagged aSyn versions indi

154 Through pulse-chase experiments with halogenated thymidine analogs, we

155 Pulse-chase experiments with radiolabeled sugars and amino aci

156 Bromodeoxyuridine pulse-chase experiments with short survival times suggest that

157 In pulse-chase experiments, 14-3-3beta increased the synthesis of

158 In fact, as directly demonstrated by pulse-chase experiments, EECs in the vascularized, but not in

159 In pulse-chase experiments, either miR-33 overexpression or knock

160 In pulse-chase experiments, recycled peptidoglycan was not found

161 lecular imaging, and [(35)S]methionine pulse-chase experiments, together with lysosome (chloroquine a

162 Using pulse-chase experiments, we also discovered that the pectin ne

163 in vivo imaging and bromodeoxyuridine pulse-chase experiments, we have analyzed growth and regenerat

164 different parts of the molecule and in pulse-chase experiments, we showed that the C terminus of the

165 rved processivity in pregnenolone/DHEA pulse-chase experiments.

166 plant Pentalinon andrieuxii by (13)CO2 pulse-chase experiments.

167 ding entity precipitations and cycloheximide chase experiments.

168 on of the intermediates as revealed by pulse-chase experiments.

169 ohistochemistry, and bromodeoxyuridine pulse-chase experiments.

170 tein stability as confirmed by cycloheximide chase experiments.

171 Fluorescent pulse-chase fate-tracking documented dynamic nucleo-cytoplasmi

172 During the chase, feed was changed to an unlabeled equivalent feed

173 some insects that are used for detecting and chasing females.

174 enzyme rapidly decayed to less than 20% when chased for 3 s by the addition of ADP.

175 In this study, gulls were chased from a Lake Michigan beach using specially traine

176 Chasing HIV-1 across the genotype landscape, unequipped

177 how coevolutionary adaptations, but instead "chase" hosts based on the herbivore's own traits at the

178 Pulse-chase, immunoprecipitation/immunoblotting analyses docum

179 ung mice, LRCs were detectable after a 16-wk chase in adults.

180 During chase in ascorbate- free medium, anMan-containing HS dis

181 rol-loaded cyclodextrin for 1 h, followed by chase in serum-containing medium.

182 tivity influence a behavioral analog of loss-chasing in rats.

183 ents did not retaliate as expected (i.e., by chasing) in response to increased cheating by cleaners.

184 A desipramine chase increased (11)C-hydroxyephedrine washout from the

185 c retention was sensitive to a NET inhibitor chase, indicating a cycle of continuous NET uptake and r

186 RNA-containing replication intermediates are chased into mature mtDNA, to which they are thus in prec

187 CDP-Chase is the first identified member of a novel Nudix fa

188 Finally, a pulse-chase isotope enrichment experiment was conducted by mea

189 s substantially diluted by excess CoA in the chase, isotope recovery of a pulse of labeled CO or meth

190 Pulse-chase kinetic transport assays on four of the top-rankin

191 wild-type activity and single-turnover pulse-chase kinetics.

192 ind and initiate assembly prior to the pulse-chase kinetics.

193 s, particularly for humpback and blue whales chasing krill.

194 itoneally delivered every other day to pulse-chase label in vivo endogenous cardiac replication.

195 turnover in adipocytes using metabolic pulse-chase labeling and high resolution mass spectrometry.

196 ddressed this question using metabolic pulse-chase labeling and quantitative mass spectrometry to obt

197 Pulse-chase labeling demonstrated that the LHDeltaT dimer was

198 In the present study we use pulse-chase labeling experiments in conjunction with isolated

199 vivo lineage tracing, and HSC-specific pulse-chase labeling have provided novel insights on B1a-cell

200 In vivo pulse-chase labeling identified galactoglycerolipid pools as a

201 Pulse-chase labeling indicates that growth is heterogeneous an

202 Improved pulse-chase labeling of endogenous interphase chromosomes yiel

203 Using in vivo pulse-chase labeling of neutrophil DNA with 6,6-(2)H2-glucose,

204 Here, we describe a metabolic pulse-chase labeling protocol using 4-thiouracil combined with

205 Pulse-chase labeling showed that TRP32 is a stable protein who

206 P-tag for studying protein turnover by pulse-chase labelling.

207 r the biomedical research community to 'stop chasing Mendel?'

208 cell-surface cross-linking, FRET, and pulse-chase metabolic labeling, we demonstrate that deleting t

209 ehicle) emission levels were measured by the chasing method under real-world conditions at a depot ar

210 ct greatly, with a study employing C14 pulse-chase methodology concluding 1% annual turnover in youth

211 mino acids in cell culture (SILAC) and pulse-chase methods to generate a global quantitative map of d

212 We used fluorescence-based pulse-chase methods to visualize the fate of pre-existing (old

213 Using a novel system for pulse-chase microscopy, we have visualized the postsynthetic r

214 terminal with resistance to a NET inhibitor chase, mimicking physiologic norepinephrine turnover.

215 umptions and restrictive models in the pulse-chase model artificially eliminated high-turnover soluti

216 Similarly, the pulse-chase model was acutely sensitive to assumptions of inst

217 ressed in a tetracycline (Tet)-based protein chase model, constitutive heat shock cognate 70 (Hsc70)

218 Previously, a pulse-chase monitored by quantitative mass spectrometry method

219 Three-station bolus-chase MR angiography with real-time fluoroscopic trackin

220 hippocampal dentate gyrus, using dual pulse-chase, multicolour gamma-retroviral tracing, transmissio

221 A predator chasing multiple prey exemplifies how goals can dynamica

222 , we employed an inducible transgenic "pulse-chase" murine model (K5Tta x TRE-H2BGFP) to localize, pu

223 Pulse-chase, Northern blotting, and primer extension analyses

224 el and then administered a second, sublethal chase of acetaminophen to accomplish "washout" of label

225 g a combination of lineage tracing and pulse-chase of actively proliferating chondrocytes, we here de

226 The chase of MinD by MinE creates the in vivo oscillator tha

227 ertial technology to record 1,119 high-speed chases of all members of a pack of six adult African wil

228 Chasing behavior, and the latencies to chase or quit, during sequences of unfavorable outcomes

229 swapped leader-follower roles and performed chases or coordinated manoeuvres by copying the heading

230 After a 6 d chase period, c. 26.8% of the (13) C remaining in the sy

231 Genetic labeling, followed by a chase period, showed that acinar cell replacement is not

232 When the pulse was followed by a chase period, the labeled polysaccharides of the Golgi m

233 (ELCs) were label-retaining after a 140-day chase period.

234 tention of proliferation markers during long chase periods (i.e., they are label-retaining cells [LRC

235 exposure, as demonstrated with 2- or 4-week chase periods after labeling.

236 eling of the label-retention data during the chase phase supported the existence of a slowly cycling

237 collected at defined times during pulse and chase phases.

238 Pulse-chase photoconversion experiments show that molecules ca

239 dual-reporter human cell lines and devised a chase protocol to quantify proteasomal degradation of a

240 A BrdU pulse-chasing protocol was also introduced as an additional as

241 oration into replicating viral DNA and pulse-chase protocols, we found that viral DNA synthesis occur

242 n, claudin strands break and reanneal; pulse-chase-pulse analysis using SNAP-tagged claudins showed p

243 Pulse-chase-pulse experiments with BrdU and EdU, and DNA conte

244 a combination of RNA footprinting and pulse-chase quantitative mass spectrometry paints a picture of

245 AV-infected cells and biochemically by pulse-chase radiolabeling experiments.

246 and fibroblasts from a human patient, pulse-chase radiolabeling of newly synthesized proteins is use

247 Pulse-chase radiolabeling reveals that a ypk1Delta mutant exhi

248 n, while the half-life was measured by pulse-chase radiolabelling.

249 resent several lines of evidence (from pulse-chase, rapid chemical quench-flow, and stopped-flow fluo

250 ride significantly reduced the proportion of chase responses, and the mean number of consecutive chas

251 esponses, and the mean number of consecutive chase responses, in a dose-dependent manner.

252 riods twice as long as signaled originally ('chase' responses).

253 c analysis using 14-C tracers and 33-P pulse-chasing revealed mutation-associated changes in purine n

254 approaching conspecific, even though it was chasing salmon, not threatening.

255 ngs demonstrate that single time point pulse-chase SILAC mass spectrometry-based proteomics (pSILAC M

256 Using a pulse-chase SILAC mass spectrometry-based proteomics approach,

257 in rats were measured in vivo using a pulse-chase stable isotope labeling experiment.

258 Use of high-level cooperative chase strategies (coordination and collaboration) was no

259 Using a dual pulse-chase strategy comparing palmitate and protein half-live

260 maps of protein synthesis as well as a pulse-chase strategy for determining rates of translation elon

261 We used a load-chase strategy to study the mechanisms that promote long

262 Pulse-chase studies confirmed impaired secretion and increased

263 Pulse-chase studies found that CYP2E1 protein level is upregul

264 Pulse-chase studies indicate that PINK1 is rapidly processed i

265 Pulse-chase studies of isotopically labeled AChE molecules sho

266 3 chk mutant/rx3 morphant fish and EdU pulse-chase studies reveal that rx3 is required to select tube

267 Pulse-chase studies showed that osterix-expressing osteoblast

268 In contrast, pulse-chase studies with isotope-labeled nutrients revealed im

269 Here, we report pulse-chase studies, which unambiguously establish the order i

270 VHL, as shown by protein stability and pulse-chase studies.

271 Pulse-chase study showed that 14-3-3zeta siRNA decreased the a

272 Using a tetracycline-regulated pulse-chase system, we measured population turnover rates and

273 nvestigated in perfused rat liver by a pulse chase technique.

274 le histone2B-green fluorescent protein pulse-chase techniques, we identify a label-retaining cell pop

275 al change, a greater amplitude for the pulse-chase than the pulse-quench reaction, and an activation

276 oresis force ensues as the cargo perpetually chases the ATPase gradient, allowing the cargo to essent

277 ne resistance by binding to the ribosome and chasing the drug from its binding site.

278 tetracycline by binding to the ribosome and chasing the drug from its binding site.

279 Chasing the phosphoenzyme at 0.4 M KCl and 2 degrees C w

280 If a copper chelator is added with the ATP chase, the initial burst is smaller, and further cleavag

281 In PRT assays, one measures, during a chase, the ratio of a test protein to a long-lived refer

282 This lipid-bound precursor can be chased through the Tat translocons under conditions of h

283 Modeling loss-chasing through analogous behaviors in rats could facili

284 nd then blocked in second cytokinesis during chase to determine distribution of immortal versus newly

285 tiple short, high-speed, mostly unsuccessful chases to capture prey, while cheetahs (Acinonyx jubatus

286 xpression followed by cycloheximide or pulse-chase treatment demonstrated that phospho-mutants exhibi

287 eome misfolding stress is applied in a pulse-chase-type experiment.

288 Ever since Hershey and Chase used phages to establish DNA as the carrier of gen

289 Using pulse-chase vital dye labeling to mark newly forming teeth in

290 ediastinum ratio, 1.99 +/- 0.12 (desipramine chase) vs. 2.05 +/- 0.16 (controls), not statistically s

291 dult mice administered (15)N-thymidine pulse-chase, we find that proliferating crypt cells dilute the

292 cetaceans and pinnipeds accomplish deep-sea chases, we deployed animal-borne instruments that record

293 ion were usable, as when predators abandon a chase when sure of the prey escaping.

294 and the Child Heart Health Study in England (CHASE), which studied 9-10 year-old children (538 Indian

295 ntially outweighs the cost of multiple short chases, which indicates that African wild dogs are more

296 Decay of [(32)P]phosphoenzyme following chase with non-radioactive ATP occurs with an initial bu

297 lanthraniloyl)adenosine-5'-O-diphosphate and chased with ADP, the SRX is not seen, indicating that tr

298 hioacetimidate (SMTA) for pulse time, t, and chased with excess of S-methyl thiopropionimidate (SMTP)

299 he right pSTS, compared with (1) a wolf that chases with a single unchanging intention, (2) very simi

300 Here, we combine H2B-GFP-based pulse-chasing with cell-surface markers to distinguish quiesce