ライフサイエンスコーパス: assembly

1 s could potentially precipitate inflammasome assembly.

2 amatic impact on polymer properties and self-assembly.

3 inhibits RhoA activation and focal adhesion assembly.

4 ote actin retrograde flow and focal adhesion assembly.

5 one growth stimulation is achievable by this assembly.

6 ty and functional diversity of the microbial assembly.

7 uired to separate centrosomes during spindle assembly.

8 active groups or groups that can prompt self-assembly.

9 tion of CypD increased high order synthasome assembly.

10 5) of mature (pseudo)pilins is essential for assembly.

11 nd results with regard to SLC sequencing and assembly.

12 nd upon previous studies characterizing vRNA assembly.

13 (Cse4) nucleosome deposition and kinetochore assembly.

14 and Fermi for error correction and sequence assembly.

15 he possibility of an amorphous gyroid's self-assembly.

16 the role of AAP and the nucleolus in capsid assembly.

17 tic centromere specification and kinetochore assembly.

18 its expression and availability for receptor assembly.

19 roles in the replication cycle such as viral assembly.

20 P in vitro, and propose a model for U6 snRNP assembly.

21 ia, indicating a common mechanism for Z-ring assembly.

22 ffold that modulates receptor kinase complex assembly.

23 in-branching growth of DNA dendrimer by self-assembly.

24 for enabling novel forms of guided molecular assembly.

25 rotein capsomers in the growing shell during assembly.

26 tion of both pre- and postsynaptic molecular assembly.

27 conformational changes stabilizing the dimer assembly.

28 r efficient DNA synthesis-coupled nucleosome assembly.

29 aits or other processes underlying community assembly.

30 some, but not all, aspects of virus particle assembly.

31 sphatase that facilitates proper kinetochore assembly.

32 distinct functions in different heterotrimer assemblies.

33 cation, morphology and size of the resulting assemblies.

34 understanding the cytotoxicity of pathogenic assemblies.

35 rm the assembly process and result in better assemblies.

36 olding is needed to achieve chromosome-level assemblies.

37 ges the ability of p17 to form soluble toxic assemblies.

38 f-organization and mechanics of cytoskeletal assemblies.

39 through halogen bonding, forming oligomeric assemblies.

40 nsient and heterogeneous noncovalent protein assemblies.

41 he D-periodic banding of higher-order fibers assemblies.

42 classifying sequences in eukaryotic de novo assemblies.

43 nchronous and coordinated with daughter cell assembly(2,3).

44 This approach also performs sequence assembly across multiple breakpoints simultaneously, ena

45 neficial both for the developers of scaffold assembly algorithms and for the researchers focused on i

46 her annotation tracks, the additional genome assemblies and an embedded VISTA genome comparison viewe

47 ous manual curation to achieve near complete assembly and accurate annotation of genomes.

48 NF-kappaB pathway, NLRC3 interferes with the assembly and activity of the NALP3 inflammasome complex

49 availabiity for very low density lipoprotein assembly and allows homeostatic control of serum triglyc

50 he nucleocapsid acts as a scaffold for virus assembly and as a template for genome transcription and

51 ve centromeres are necessary for kinetochore assembly and cell-cycle progression.

52 Cation-pi interactions drive the self-assembly and cohesion of many biological molecules, incl

53 ale structures open up new possibilities for assembly and control of nanodevices and biomolecules.

54 ucleated erythrocytes, due to impaired actin assembly and cytoskeleton stability.

55 We report here the synthesis, assembly and cytotoxicity evaluation of self-assembling

56 ding of the role of ionic correlations in NP assembly and design rules to utilize the salting-out pro

57 Actin filament assembly and disassembly are vital for cell functions.

58 ng multiple rounds of pre-initiation complex assembly and disassembly before productive elongation of

59 terologous system to compare their intrinsic assembly and dynamic properties.

60 face, is important in both influenza A virus assembly and entry.

61 synthesis of the subunits and their correct assembly and expression at the plasma membrane as a sing

62 alose, a known autophagy enhancer, delays SG assembly and facilitates their premature post-stress dis

63 However, is Mena(INV) involved in TMEM assembly and function?

64 nd M2 proteins play important roles in virus assembly and in the morphology of virus particles.

65 -infected cells to daclatasvir reduced viral assembly and induced clustering of structural proteins w

66 neurotransmission is unnecessary for synapse assembly and maintenance.

67 petitive nature poses a challenge for genome assembly and makes progress on the detailed study of sat

68 The assembly and mechanics of actomyosin stress fibers (SFs)

69 ion plays an essential role in the flagellar assembly and motility of T. denticola.

70 on the target protein of interest, nanodisc assembly and purification can be achieved within 12-24 h

71 rRNA dynamics underlie the hierarchy of 30S assembly and simplify the search for the native ribosome

72 ssential roles in cytochrome c oxidase (COX) assembly and the regulation of copper homeostasis.

73 se results enhance our understanding of vRNA assembly and the role of cytoskeletal proteins in that p

74 can assemble simultaneously during early 60S assembly and underscore the enormous complexity of 60S s

75 eins are believed to assist with Clp complex assembly and/or to promote complex stability.

76 vation, nonmuscle myosin II bipolar filament assembly, and actin retrograde flow at the T-cell-substr

77 nto polymorphic capsids, whose architecture, assembly, and stability are still being investigated.

78 Advances in genome sequencing and assembly are being used to access the large and complex

79 wed that energetics and kinetics of NTD self-assembly are highly conserved across spider species desp

80 nteract with the portal protein during motor assembly, as predicted for several bacteriophages.

81 man organisms enabled de novo mtDNA sequence assembly, as well as detection of previously unknown mtD

82 The results here demonstrate that the T4P assembly ATPase PilB functions as an intermediary in the

83 tracking and a tool for managing the genome assemblies available to perform an analysis.

84 erential regulation by two distinct mSWI/SNF assemblies, BAF and PBAF complexes, enhancers and promot

85 genome base and gene coverage, transcriptome assembly base coverage, number of chimeras and number of

86 In the pipeline, Burrows-Wheeler Aligner and Assembly Based ReAlignment are used for small and large

87 the largest-scale policy shift, California's Assembly Bill 60 (AB60), under which more than 600,000 l

88 KIF20B is not required for midbody assembly, but may accelerate or coordinate midbody matur

89 PYD-only protein POP2 inhibits inflammasome assembly by binding to ASC and interfering with the recr

90 structures, indicating broad control of CCP assembly by Ca(2+) signals.

91 ed its tissue distribution and extracellular assembly by immunohistochemistry and immunofluorescence

92 e of frustrated growth of the supramolecular assembly by tuning the balance of attractive and repulsi

93 lustrate this method, which we term 'fractal assembly', by producing DNA origami arrays with sizes of

94 rtant insights into genome packaging, virion assembly, cell entry, and other stages of the viral life

95 earing capacity and silencing of the spindle assembly checkpoint.

96 ighlights, including out-of-equilibrium self-assembly, chemically fuelled molecular motion, compartme

97 ed to design other quasicrystal-forming self-assembly chemistries and processes.Probing the growth pa

98 imulations of this model predict that sparse assembly codes emerge in this microcircuit motif under s

99 lathrin accumulated in the cytoplasmic virus assembly compartment (vAC) of infected cells co-localizi

100 The linear ubiquitin chain assembly complex, LUBAC, is the only known mammalian ubi

101 step process, which relies on macromolecular assemblies composed of 15 conserved proteins in model gr

102 he past 20 years it has been found that some assemblies contain long flexible regions that adopt mult

103 We present a hierarchy of assembly criteria based on crystallographic observations

104 r impaired of TAG hydrolysis show spore wall assembly defects, supporting a role for TAG and/or its m

105 informatic pipeline and laptop-based genomic assembly demonstrated the feasibility of sequencing anal

106 Such self-assemblies describe not only the basic structural motif

107 ion patterns by Abeta1-28WT and Abeta1-28A2V assemblies differed in shape and position of the equator

108 changes are often part of a bigger community assembly dynamic.

109 rk regulates several key variables of PbS NC assembly (e.g., NC concentration and solubility, solvent

110 ilms via the electrochemically assisted self-assembly (EASA) technique.

111 e that the synchronous oscillations in these assemblies emerge from interplay between intrinsic membr

112 re the nucleation event of infectious virion assembly, ensuring that one RNA dimer is packaged into e

113 cribing the role of MT in vRNA transport and assembly expand upon previous studies characterizing vRN

114 Chromatin assembly factor 1 (CAF-1) is the histone chaperone respo

115 strain, we show that the requirement for the assembly factor depends on the cellular redox environmen

116 Depletion of the assembly factor Erb1 prevents stable assembly of seven o

117 COX18 is an additional COX2 assembly factor that belongs to the Oxa1 family of membr

118 ive hepatopathy due to mutated BCS1L, a CIII assembly factor.

119 table assembly of seven other interdependent assembly factors with pre-60S subunits, resulting in tur

120 The self-assembly feature enhances biodistribution and the half-l

121 lative to the previous reference genome, our assembly features a 52-fold increase in contig length an

122 we present draft de novo genome and plastome assemblies for a wilt-resistant South African accession

123 uced a comprehensive annotated transcriptome assembly for L. granatensis.

124 strategy based on amphiphilicity-driven self-assembly for the crafting of high aspect ratio, 2D sheet

125 Here, we report on a high-quality genome assembly for the K. marmoratus South Korea (SK) strain h

126 e), are required to control ubiquitin ligase assembly, function, and ultimately substrate degradation

127 ts have accelerated our understanding of its assembly, function, evolution, and its role in human dis

128 tructure dynamics and heterogeneity of viral assemblies have revealed important insights into genome

129 presence, nitrogen availability, and fungal assembly history.

130 numerous methods and techniques for scaffold assembly, identifying similarities and dissimilarities a

131 te viral proteins may be critical for virion assembly.IMPORTANCE Poxviruses are unique among envelope

132 n significantly alter the efficiency of self-assembly in a biological context.

133 nded model of processive VASP-mediated actin assembly in clustered arrays.

134 that CRMP-1 is a major contributor to actin assembly in epithelial cells, where it works with the En

135 vealed Aire's critical functions for spindle assembly in preimplantation embryos.

136 Distinct controls of NC assembly in solvent with variable concentrations confirm

137 ecies represented and their highly organized assembly in the crystal lattice.

138 anistic understanding of eukaryotic ribosome assembly in the model organism Saccharomyces cerevisiae.

139 Controlling supramolecular self-assembly in water-based solutions is an important proble

140 einvigorate studies of 14-3-3/phosphoprotein assemblies, including those with challenging low-affinit

141 hannel current recording, we define discrete assembly intermediates and show that the pore is most pr

142 rial materials by integration of the peptide assemblies into tissue scaffolds.

143 latform for genetically pre-programming self-assembly into micelles of varied size and shape.

144 The stability of these assemblies is a result of significant levels of cooperat

145 Correct outer protein shell assembly is a prerequisite for virion infectivity in man

146 De novo transcriptome assembly is an important technique for understanding gen

147 kageable viral RNA is not required for virus assembly is currently unknown.

148 dent, centrosome-independent mitotic spindle assembly is essential for the survival and proliferation

149 Self-assembly is likely to play an important role in the cons

150 e mechanism of intracellular dynamics of IAV assembly is necessary to understand reassortment.

151 ation of metabolites revealed that acylsugar assembly is not conserved between tomato and petunia.

152 form micron-scale structures with CM2, whose assembly is stimulated by Plk1 phosphorylation in vitro.

153 Assembly is triggered by the formation of a disulfide bo

154 essential for pilin membrane extraction and assembly, is followed by N-methylation of the mature (ps

155 This has implications for the assembly kinetics, morphology, and toxicity of all Abeta

156 ant multidomain enzymes responsible for the "assembly line" biosynthesis of many genetically encoded

157 ual reactions can be compared and underlying assembly-line logic can emerge.

158 lyketide products, structural aspects of the assembly-line machinery itself are considered.

159 ng the loading, extension, and offloading of assembly lines that construct primarily polyketide produ

160 of a protein involved in lipopolysaccharide assembly, lptD4213, is synthetically lethal with the del

161 The beta-barrel assembly machinery (BAM) is a conserved multicomponent p

162 the mitochondrial iron-sulfur (Fe/S) cluster assembly machinery resides to mature mitochondrial Fe/S

163 We demonstrate that perturbations of this assembly machinery trigger complex cellular responses th

164 This revealed four beta propellers, in an assembly markedly similar to those of other protein comp

165 dings suggest that both PGC1alpha and capsid assembly may represent attractive targets for the develo

166 Little is known, however, about the assembly mechanism and activation of the HerA-NurA.

167 erials can undergo intrinsically driven self-assembly, metaphorically pulling themselves up into exis

168 the power and potential of our one-pot gene-assembly method by preparing an epigenetically modified

169 imize operator intervention, a non-enzymatic assembly method is highly desirable.

170 NA sequences and experimental protocols, our assembly method is readily accessible and will facilitat

171 We compare our results to a network assembly model that admits tunable trophic coherence via

172 ling strategy enabling more accurate protein assembly models.

173 osomal subunits, some portion of 30S and 50S assembly must occur in the context of the 70S ribosome.

174 rcular dichroism studies indicated that self-assembly occurs at concentrations as low as 0.01 muM.

175 Magnetotactic bacteria form assemblies of magnetic nanoparticles called magnetosomes

176 rimental results that show that proteins are assemblies of small cooperative units called foldons and

177 r the researchers focused on improving draft assemblies of specific organisms.

178 nt biomolecular substrates for the templated assembly of a functional RNA structure.

179 s a component of BM, collagen IV enabled the assembly of a fundamental architectural unit for multice

180 induces conformational changes that promote assembly of a high-activity oligomer.

181 independent signalling mechanism that drives assembly of adherens junctions, and confirm these findin

182 The defined assembly of all components using a modular design result

183 rogress on the molecular and mesoscopic self-assembly of amyloid-beta, alpha synuclein, human islet a

184 Co-assembly of binary systems driven by specific non-covale

185 develop new chemical ligation strategies for assembly of biocompatible modified DNA, we have synthesi

186 Temperature-induced self-assembly of block copolymers allows the formation of sma

187 determining capsid structure during the self-assembly of CCMV-like particles.

188 In addition to control of initiation and assembly of CCPs, EGF stimulation also elicited a Ca(2+)

189 nd l-lactic acid, which is important for the assembly of cell walls in many microorganisms.

190 The assembly of charged nanoparticles (NPs) and proteins in

191 as proven a versatile tool to guide the self-assembly of defects such as scars, pleats, folds, bliste

192 recessive disorder frequently caused by non-assembly of dynein arm motors into cilia and flagella ax

193 e to heat and salt is a critical step in the assembly of elastic fibers in vivo, preceding chemical c

194 on transfer from a donor excited state to an assembly of electronically coupled acceptors has been pr

195 icate Jmjd2c as a molecular scaffold for the assembly of essential enhancer-protein complexes with an

196 vercome the weaknesses of short reads in the assembly of eukaryotic genomes; however, at present addi

197 ing domain for integrins GFOGER reverted the assembly of FN induced by MGO-treated collagen.

198 aldolase-catalyzed reactions enables one-pot assembly of gamma-nitroketones from three simpler buildi

199 es with ODNs, which were used to mediate the assembly of gold nanoparticles.

200 e 8-pore devices to analyze in real time the assembly of Hepatitis B Virus (HBV) capsids below the ps

201 his raises important questions about how the assembly of IL-12 family members is regulated and contro

202 ontig length and notable improvements in the assembly of intergenic spaces and centromeres.

203 ptide conjugates obtained by hierarchical co-assembly of L,L-diphenylalanine (FF) and zinc phthalocya

204 This demonstration can also enable the assembly of large scale quantum information systems and

205 growth in cell culture due to a reduction in assembly of mature virions.

206 r frontier in understanding the evolutionary assembly of modern vertebrate diversity.

207 ection of Tau inclusions induces the ordered assembly of monomeric Tau, followed by its spreading to

208 l) templates, the amphiphilicity driven self-assembly of nanoparticle vesicles from polymer-grafted c

209 ral motif can be exploited to guide the self-assembly of naphthalene diimide and perylene diimide ele

210 ine-scale synapse formation and microcircuit assembly of neocortical interneurons.

211 s, and its depletion disrupts the functional assembly of Orai1 multimers.

212 ing similar RNA-RNA interactions that govern assembly of other segmented RNA viruses.

213 Gels, in particular those obtained via self-assembly of pi-conjugated molecules, are dynamic materia

214 Self-assembly of plasma membrane-associated Ras GTPases has m

215 The assembly of PNNs coincides with the end of the period of

216 Supramolecular polymerization or assembly of proteins or large macromolecular units by a

217 a dynamic process that involves the ordered assembly of ribosomal proteins and numerous RNA structur

218 nomers to accelerate phosphorylation-related assembly of RSs and entire flagella.

219 of the assembly factor Erb1 prevents stable assembly of seven other interdependent assembly factors

220 These observations indicate that the self-assembly of small molecules, as multifaceted entities an

221 Assembly of the ASC speck is critical for signaling by t

222 h is the subunit of ESCRT-III that initiates assembly of the complex.

223 pid GTP hydrolysis by monomeric Cdc10 drives assembly of the core Cdc10 homodimer.

224 ide the symmetry adaptation required for the assembly of the entire secretion machine.

225 omega-dicarboxylic acid pimelate moiety and assembly of the fused heterocyclic rings.

226 xisting data and present a new model for the assembly of the HIRA complex and for the HIRA-mediated i

227 This is the first long-read sequence assembly of the horse MHC class II region with rigorous

228 Assembly of the inflammasome allows for the cleavage and

229 t is crucial for higher order structure self-assembly of the key intrinsically disordered EMPs, amelo

230 ur results show how E-cadherin instructs the assembly of the LGN/NuMA complex at cell-cell contacts,

231 We used this line to describe the assembly of the major vessels of the trunk lymphatic vas

232 paRNA, with the risk allele facilitating the assembly of the microRNA-guided Argonaute 1 complex and

233 The self-assembly of the microtubule associated tau protein into

234 ies a novel protein that plays a role in the assembly of the mitochondrial respiratory chain.

235 ial cells, P2X7R activation also induces the assembly of the NLRP3 inflammasome and the maturation an

236 e is built upon in the automated solid-phase assembly of the oligorhamnan fragments.

237 itment for four of the studied proteins, the assembly of the other two is irreversible and enhanced a

238 generate a SUMO-SIM network that facilitates assembly of the RC.

239 Utilizing colloidal particles for the assembly of the shell of nano- and microcapsules holds g

240 ew captures the progress of the hierarchical assembly of these NCs, which bridges the link between th

241 nd subunit complexity of the proteasome, the assembly of this 2.5MDa complex must be carefully orche

242 Assembly of this cofactor requires O2, Fe(II), and a red

243 The process of molecular recognition is the assembly of two or more molecules through weak interacti

244 Its crystal structure revealed the self-assembly of two Pt-centered Ag icosahedra through vertex

245 ned at the atomic scale using layer-by-layer assembly of two-dimensional building blocks under vacuum

246 zyme Usb1, reconstitute post-transcriptional assembly of yeast U6 snRNP in vitro, and propose a model

247 reparation of molecular chromophore-catalyst assemblies on wide bandgap semiconductors.

248 A SnO2 bridged assembly on SnO2/TiO2 core/shell electrodes undergoes li

249 hat these mutations perturb protein folding, assembly or polarity of secretion of C1QTNF5 and, import

250 al chromosomes, and gross defects in spindle assembly or stability.

251 A complex assembly pathway conducts their initial synthesis and su

252 ns that intercede at different stages of the assembly pathway.

253 develop a summative model wherein the P-body assembly phenotype of a given mutant can be predicted fr

254 lustering is a useful initial step for other assembly pipelines.

255 receptors mediating an inhibition of synapse assembly, plasticity, and learning.

256 rotype-dependent heterogeneity of the capsid assembly process and challenge current notions about the

257 provides useful insights that can inform the assembly process and result in better assemblies.

258 This ordered assembly process shepherds primary transposase binding t

259 network positions through time, causing the assembly process to be punctuated by major network reorg

260 een the history of environmental conditions, assembly processes and microbial community dynamics is n

261 ying similarities and dissimilarities across assemblies produced by different methods is beneficial b

262 ed for the same individual allowed assessing assembly properties and pinpointing misassemblies.

263 the mitochondrial oxidoreductase import and assembly protein 40 (AtMIA40), forming a protein complex

264 The crystal structure of this inactivated assembly provides first insight into the binding interac

265 We measured the assembly quality in terms of reference genome base and g

266 s, we herein report reference-based ribosome assembly (RAMBL), a computational pipeline, which integr

267 target sites, they form different oligomeric assemblies ranging from monomers, dimers, tetramers to h

268 on (i.e., pathway complexity), and where the assembly rates are of key importance.

269 substitution strategy to determine structure-assembly relationships of 76 different Abeta40 and Abeta

270 however, fundamental aspects of AAV's capsid assembly remain poorly characterized.

271 nostructures are often organized using local assembly rules that produce long-range order.

272 omparison including the published short-read assembly (SR) constructed for the same individual allowe

273 Co Prism is obtained in one self-assembly step that organizes six total building blocks,

274 We report the discovery of self-assembly strategies leading to the emergence of lipid bi

275 been made in the understanding of proteasome assembly, structure, and function.

276 cally arranged in chains, but other forms of assemblies such as clusters can be observed in some spec

277 membrane segments, with consequences for the assembly, surface expression, and function of the polycy

278 sions (FAs) are integrin-based transmembrane assemblies that connect a cell to its extracellular matr

279 eria, some of these pumps form multi-protein assemblies that span the cell envelope.

280 Many tools have been developed for haplotype assembly-the reconstruction of individual haplotypes usi

281 esults show that PTEN controls multicellular assembly through a membrane-associated regulatory protei

282 in part by disturbing the ability of neural assemblies to synchronize.

283 rgy-transport processes occurring within the assemblies to the structural organization of the pi-syst

284 iological and synthetic systems exploit self-assembly to generate highly intricate closed supramolecu

285 Here we demonstrate self-assembly to nanoscale cuboidal particles with a bicontin

286 Spt6 coordinates nucleosome dis- and re-assembly, transcriptional elongation, and mRNA processin

287 and the R, Qa, and Qc SNAREs, and that this assembly undergoes rapid fusion upon addition of Qb and

288 ding of the molecular mechanisms of filament assembly, we have used a synthetic biology approach to r

289 To decipher the mechanisms of IgM assembly, we investigated its biosynthesis in living cel

290 Thus, we propose a model of MET complex assembly where Tomt and the Tmcs interact within the sec

291 zing such films is sequential layer-by-layer assembly, whereby atomically thin two-dimensional buildi

292 ert to more closely packed membrane nanopore assemblies, which can subsequently recruit additional pr

293 ver the complex multistage process of capsid assembly, which involves recruitment and complexation, f

294 struct asymmetric and dynamic hetero-vesicle assemblies with complex DNA nano-scaffolds.

295 Z-ring formation and may help coordinate its assembly with chromosome replication and segregation.

296 monolayer, and, when jammed, offer a robust assembly with exceptional mechanical properties.

297 s alpha6 synaptic localization by preventing assembly with GARLHs/NL2.

298 d respiratory syncytial virus particles, and assembly with genomic ribonucleoproteins and caveolae-as

299 (overall 53%) using coordination-driven self-assembly with no chromatographic purification steps.

300 ower tissues, and performed de novo sequence assembly, yielding 98,613 unique transcripts with an N50