ライフサイエンスコーパス: abrogate

1 ved, but their ability to induce invasion is abrogated.

2 , and its pulsatile translocation is largely abrogated.

3 ost-injection; n=3), which was significantly abrogated (2.3+/-0.5%ID/g at 48h post-injection; n=3) wh

4 s in vivo We conclude that it is possible to abrogate a specific co-chaperone function of Hsp90 witho

5 lines in order to identify new mechanisms to abrogate acquired SR as well as new potential therapeuti

6 how that elimination of the ACT-PLA activity abrogates ACT toxicity in macrophages, particularly at t

7 nger bind to VWF D4-CK, and deletion of TSP8 abrogated ADAMTS13 conformational activation.

8 Porcine-NICC xenograft tolerance was abrogated after depletion of Foxp3Treg cell.

9 egulation of the levels of active Notch1 was abrogated after silencing ERbeta.

10 An anti-TSLP antibody abrogated airway hyperresponsiveness, inflammation, and

11 An anti-TSLP antibody abrogates all pathologic features of asthma in this mode

12 of angiogenesis, in retinal endothelium and abrogate angiogenesis in the mouse models of oxygen-indu

13 EGFR2 locus using rAAV1-mediated CRISPR/Cas9 abrogates angiogenesis in the mouse models of oxygen-ind

14 et ACE2 expression is sparse, its inhibition abrogates angiotensin-(1-7)-mediated GSIS.

15 matory monocytes and their derivatives would abrogate anti-myeloperoxidase (MPO) antibody-induced NCG

16 of AML cells both in vitro and in vivo, thus abrogating any potential chemoresistance mechanisms invo

17 logical targeting of apelin cognate receptor abrogates apelin- and endothelial-mediated expansion of

18 the AR interaction domain or loss of Bag-1L abrogate AR signaling and reduce PCa growth.

19 Tcf1 long isoforms in mice (p45(-/-)mice) to abrogate beta-catenin interaction.

20 in the hemagglutinin (HA) glycoprotein that abrogate binding of human antibodies.

21 Substitution of Lys51 to Ala in LC3B abrogates binding of a phosphomimetic Nix mutant.

22 a mutation in the TR DNA-binding domain that abrogates binding to DNA and leads to complete loss of c

23 ion of the phospho-deficient Pg-mutant S665A abrogated both cAMP-mediated junctional remodeling and i

24 function for a wild-type polyQ tract that is abrogated by a competing longer polyQ mutation in a dise

25 This effect was abrogated by a GABAA-R antagonist.

26 ory cytokine production in a manner that was abrogated by anti-PD-L1 blocking antibody.

27 tivation of the neutrophil NADPH oxidase was abrogated by bacterium-derived proteolysis of galectin-3

28 c capacity of Th17 cells to transfer EAU was abrogated by BET inhibitors in an adoptive transfer mode

29 component of FIV that is Kir independent is abrogated by blocking Ca(2+) -sensitive K(+) channels.

30 This latter interaction was abrogated by blocking protein kinase C activity, resulti

31 uM) stimulated proliferation, which could be abrogated by capsazepine.

32 is chemoreflex anti-inflammatory network was abrogated by carotid chemoreceptor denervation and by ph

33 villous trophoblasts, and this induction was abrogated by CH223191, an aryl hydrocarbon receptor (AhR

34 dependent on bacterial CDDL expression, and abrogated by cotreatment with the antibiotic ciprofloxac

35 owth promotion and myelin disinhibition were abrogated by CRMP2 inhibition and largely mimicked in WT

36 avoidance and hyperactivity, phenotypes not abrogated by cross-fostering to control mothers.

37 This constitutive activation was abrogated by ex vivo treatment with the janus kinase 1/2

38 This increase was abrogated by inhibiting inositol trisphosphate-mediated

39 d carotid arteries, but this effect was also abrogated by lack of CD40 on injected platelets.

40 ammatory actions by activated platelets were abrogated by lack of CD40 on injected platelets.

41 creases lung metastasis in vivo, and this is abrogated by miR-452 overexpression.

42 op region in the C-type lectin domain and is abrogated by mutation within the domain.

43 nd can be reconstituted with beta-glucan and abrogated by neutralization of IL-17A.

44 uced osteoclast resorptive function, effects abrogated by neutralizing anti-IFN-gamma antibodies.

45 ile in the remaining cases, TP53 activity is abrogated by other oncogenic events, such as hyperactiva

46 ation and ATP production, an effect that was abrogated by phosphocreatine-mediated reactivation of th

47 ed BBB disruption and neuroinflammation were abrogated by pretreatment with the rho kinase inhibitor

48 Such infiltration and tumor regression were abrogated by silencing CCL5 in BECN1-defective tumors.

49 1 ligand (CD274), and these differences were abrogated by sustained CD274 blockade.

50 ised of Th1, Th17, and Th22 cells, which was abrogated by the addition of anakinra.

51 dams provoked pregnancy loss, which could be abrogated by the adoptive transfer of IL-10(+/+) NK cell

52 ar localization of P. pastoris MS (PpMS) was abrogated by the deletion of 107 C-terminal amino acids

53 This essential function could be abrogated by the dominant-negative effect of HOXD10 as s

54 gnostic impact of chemotherapy resistance is abrogated by the implementation of early response-based

55 These Ca(2+) increases were abrogated by the MS channel inhibitor Grammostola spatul

56 organoid proliferation and crypt budding was abrogated by the Wnt inhibitor IWP2.

57 TBBPA diminished and eventually abrogated Ca(2+) transients, altered intracellular Ca(2+

58 dered sterile, it is crucial to discover and abrogate causes as best possible, provide reliable and e

59 sults in reduction of mitochondrial mass and abrogates cellular bioenergetics during degeneration of

60 ivated Cl(-) currents, but unexpectedly also abrogates CFTR-mediated Cl(-) secretion and completely a

61 p53-dependent and -independent mechanisms to abrogate checkpoints that prevent conversion of differen

62 Furthermore, this abrogated constitutive activity of 5-HT2B/C receptors an

63 VACV-138 also abrogated D8 binding to the high-affinity ligand CS-E, b

64 ably, silencing of RNA sensors RIG-I or MDA5 abrogated DC maturation, as well as cytokine responses b

65 etic deletion of Nalp3, which encodes NLRP3, abrogated defects in solute transport during acute perit

66 lmethane treatment restored memory deficits, abrogated development of neurological signs, prevented n

67 Interestingly, MCC950 treatment abrogated disease signs in mice infected with a related

68 ngly, blockade of the EGF receptor partially abrogated Dkk1-mediated hematopoietic recovery.

69 g 2 (MSH2), a mismatch repair (MMR) protein, abrogated early inflammation-induced epigenetic alterati

70 c mutS chromosomal alleles that specifically abrogate either regulatory pathway or both, we demonstra

71 RB action is abrogated either by direct depletion or through inactiva

72 expression of either the N- or C-lobe of CaM abrogated estrogen-stimulated transcription of the estro

73 Adiponectin receptor agonists abrogated ex vivo fibrotic responses in explanted normal

74 nsfer of wild-type or p110delta(D910A) Tregs abrogated exaggerated neutrophil activity, increased neu

75 QC6352 also abrogated expression of EGFR, which drives the growth of

76 called "Affimer" that block IgG binding and abrogate FcgammaRIIIa-mediated downstream effector funct

77 tide identified in vivo, whereas its absence abrogates fibril formation.

78 hibitor (CD44v6 peptide) targeting of CD44v6 abrogates fibrogenesis in murine models of lung injury.

79 Histology confirmed significantly abrogated fibrosis by kaempferol and esculetin in vivo.

80 single amino acid substitutions in DAXX that abrogate formation of the complex to explore ATRX-depend

81 Loss of Jmjd2c abrogates G9a recruitment and further destabilises loadi

82 involving FAK and mutant EGFR, EGFRvIII, and abrogated gains in secreted proteases, MMP-2 and MMP-9,

83 f function via GATA4 germline mutations that abrogated GATA4 interactions with a coactivator, MED12,

84 HPV infection abrogated gene expression associated with the physical e

85 However, CGS did abrogate germinal center T follicular helper cells, and

86 am pathways, using small-molecule inhibitors abrogates GNA13-induced TIC phenotypes, rendering cells

87 n of both phoP and Sant_4061 is necessary to abrogate growth of this bacterium in an insect host.

88 Disrupting PTPRZ1 abrogated GSC maintenance and tumorigenic potential.

89 Furthermore, Znhit1 deletion also abrogates H2A/H2A.Z exchange in MPPs.

90 H3K9ac at hepcidin-associated chromatin and abrogates hepcidin suppression by erythropoietin, iron d

91 PYK2 inhibition also abrogated HER3 upregulation in response to EGFR antagoni

92 the depletion or inactivation of Akt or Skp2 abrogated Hippo signal deficiency-induced liver tumorige

93 ignificantly attenuates viral replication by abrogating hnRNP A1 interactions.

94 led to persisting TRAS in Pten(-/-) mice and abrogated hypertrophic liver growth.

95 re overload in mice lacking SRC-2 induces an abrogated hypertrophic response and decreases sustained

96 A-mediated HIF2alpha knockdown in BeWo cells abrogated hypoxia-associated decreases in PlGF secretion

97 Targeted therapeutics, such as those abrogating hypoxia inducible factor (HIF)/vascular endot

98 ation of purified malaria pigment with DNase abrogated IFN-beta induction.

99 -AS1, or one IFNG enhancer-associated lncRNA abrogates IFNG expression by memory T cells, indicating

100 grin ligation with an RGD-containing peptide abrogated IL-13-enhanced contraction, with no further ef

101 hibition of MRE11, but not depletion of ATM, abrogated IL-33 stimulation.

102 In vivo, recombinant HpARI abrogated IL-33, group 2 innate lymphoid cell (ILC2) and

103 e that the IL-1 receptor antagonist anakinra abrogates IL-22 production and reduces tumor growth in a

104 ysaccharide-induced inflammatory response by abrogating IL-1beta expression.

105 Conversely, abrogating IL-21 receptor signaling in donor T cells and

106 intron to express a foreign circRNA sequence abrogates immune activation, and mature human circRNA is

107 Both of these effects were completely abrogated in AID-deficient B cells.

108 B-cell reconstitution is abrogated in both syngeneic and allogeneic transplantati

109 phaIIbbeta3 activation, and aggregation were abrogated in ck2beta(-/-) platelets.

110 evice, we found that the effects of ACM were abrogated in confinement.

111 These pathologic responses were abrogated in cyclophilin D-knockout mice.

112 In contrast, disease development was abrogated in FcRgamma chain-deficient mice and markedly

113 ing inflammatory symptoms and the effect was abrogated in HCA2(-/-) mice.

114 ts of radiotherapy and STING agonists can be abrogated in humans by a translational strategy involvin

115 These functions are abrogated in lamin A/C-deficient mouse embryonic fibrobl

116 ulation of mTORC1 signaling by DNA damage is abrogated in many cancer cells, thus mTORC1 signaling re

117 ession and prostaglandin E2 release could be abrogated in metastatic breast cancer cells by inhibitio

118 ling is active in mouse ESCs grown in 2i but abrogated in serum by ERK-dependent phosphorylation.

119 fects of exogenous histamine injections were abrogated in STAT6(-/-) mice.

120 dylserine-exposing oligodendroglial cells is abrogated in the absence of ATG5.

121 tive effect of DNGR-1 deletion is completely abrogated in the absence of bone marrow-derived IL-10.

122 ing INS-1E cells, respectively, and this was abrogated in the presence of an irisin-neutralizing anti

123 that is induced by IL-10 overexpression was abrogated in this model.

124 ersely, blocking TNFalpha receptor signaling abrogated induction of MCP-1, implicating it in the anti

125 Genetic manipulations that abrogate inhibitory RORbeta IN function result in an ata

126 sulting in an impaired thrombopoiesis and an abrogated inositol 1,4,5-triphosphate receptor-dependent

127 Here we identify a mutation in HPV16 E2 that abrogates interaction with ChlR1, and we show that ChlR1

128 e found that deletion of Lon's ATPase domain abrogated interactions with DNA.

129 viruses encoding full-length NSs completely abrogated intranuclear filament formation in infected ce

130 In contrast, deficiency of alphaXbeta2 abrogated intraperitoneal recruitment and adhesive funct

131 sely, LKB1-overexpression in LKB1-null cells abrogated invasion, migration and mammosphere-formation.

132 erated by proximal tubule CD73 expression in abrogating IRI.

133 Subsequently, reduced Isl1 expression abrogated ISL1-dependent recruitment of histone deacetyl

134 Crabtree effect in Huh7 and C2C12 cells and abrogated it in mouse neuroblastoma N2A cells.

135 diated phosphorylation sites in beta-catenin abrogated its AJ localization and compromised epithelial

136 treatment with an anti-class II MHC antibody abrogated its antitumor activity.

137 ation of Tyr-60, Tyr-133, or Tyr-250 in PCNA abrogated its ubiquitination.

138 on into the growth factor domain of uPA that abrogates its binding to uPAR (Plat(GFDhu/GFDhu)) to inv

139 coccal protease SspB inactivates galectin-3, abrogating its stimulation of oxygen radical production

140 onstrated that depletion of CBL/CBL-B or LNK abrogated JAK2 ubiquitination, extended JAK2 half-life,

141 rmore, deficiency in either NLRP11 or RNF19A abrogates K48-linked ubiquitination and degradation of T

142 O reduced the expression of TGFbeta mRNA and abrogated kidney allograft acceptance.

143 increases, whereas targeted DNMT1 depletion abrogates KIT signaling cascade through Sp1/miR-29b netw

144 P deubiquitinates NALP7 and STAMBP knockdown abrogates LPS or Pam3CSK4-induced increases in NALP7 pro

145 ronic pharmacological dynein inhibition also abrogates Mbp mRNA distribution and dramatically decreas

146 ermore, depletion of p115 RhoGEF levels also abrogated MCP1- or BI-induced Rac1-NFATc1-cyclin D1-CDK6

147 n loop" in T. thermophila HAP2 were found to abrogate membrane pore formation in mating cells.

148 d in neutrophil-platelet interactions, fully abrogated metoprolol's infarct-limiting effects.

149 T1 inhibition, and MARCKS or LAMC2 knockdown abrogated migration and invasion induced by AKT1 inhibit

150 Inhibition of the channel abrogated migration of metastatic cancer cells in vitro

151 DA-MB-231 cells promoted radioresistance and abrogated miR-125-mediated radiosensitization.

152 In a mouse model of AML, the loss of Cdc42 abrogates MLL-AF9-induced AML development.

153 omerular necrosis and crescent formation and abrogated monocyte, macrophage, and dendritic cell incre

154 ma membrane, increased drug sensitivity, and abrogated MPP1-dependent hematopoietic progenitor cell r

155 n how phosphorylation of the L-selectin tail abrogates mu1A interaction.

156 a normal function of alphaS at vesicles, and abrogating multimers has pathogenic consequences.

157 (LLC), and targeting TLR4 alone effectively abrogate muscle wasting.

158 Co-blockade of both CCL9 and IL-23 abrogates Myc-induced tumor progression.

159 loss of trehalose dimycolate production and abrogating mycolylation of arabinogalactan.

160 Co-ligation of SIRPalpha with CD47 abrogates nanocluster segregation.

161 h the CSF-1 receptor antagonist PLX5622, and abrogated neuronal-microglial communication in CX3C rece

162 motor coordination, and working memory, and abrogated neutrophil infiltration into the injured brain

163 bud growth defects in boi mutant cells, and abrogated NoCut checkpoint function.

164 eptor's activity using a chemical antagonist abrogated not only the alterations in PPARgamma-regulate

165 the phytaspase cleavage sites in prosystemin abrogated not only the phytaspase-mediated processing of

166 epleting Kapalpha.Kapbeta1 by RanGTP further abrogates NPC barrier function, whereas adding back Kapb

167 dicate that R742A as well as D113R mutations abrogate nuclear localization of PpMS and its ability to

168 regulators, and disruption of actin dynamics abrogates nuclear transport, preventing NLS (nuclear loc

169 Notably, the IVVY motif mutation abrogated OC gene expression compared with a vector cont

170 he proliferation and migration of DPSCs, but abrogated odonto/osteogenic differentiation.

171 forced mitotic bypass through EMI1 depletion abrogates PARP-inhibitor-induced cytotoxicity.

172 Four of the six BDs abrogated PBRM1 tumor suppressor function, gene regulati

173 ods and identify new therapeutic targets for abrogating PDAC progression.

174 GSK-3 inactivation by PKB abrogates phosphorylation of Cbl-b at these two sites an

175 eraction between C-terminal module and PIF3, abrogates PHYB nuclear accumulation, photobody biogenesi

176 and IPA-3) that act via different mechanisms abrogated PKD1 phosphorylation at Ser(203), 2) siRNA-med

177 rin polymerization during clot formation, or abrogate plasma clotting.

178 ronate (PLN-alen), but not free alendronate, abrogated PLN-induced tumor growth and increased progres

179 ection by blocking viral DNA replication and abrogating postreplicative intermediate and late gene tr

180 G4-interacting residues (T1024G and T1086G) abrogated preferential binding of WRN to G4 DNA.

181 However, neutrophil depletion abrogated protection from death in Nlrp3(-/-) mice in re

182 ow that overexpression of certain chaperones abrogates protein aggregation and protects a UPR mutant

183 hRpn13 deletion from HCT116 cells abrogates RA190-induced accumulation of substrates at pr

184 Silencing thioredoxin-interacting protein abrogated reactive oxygen species accumulation in EZH2 s

185 1R(-/-) mice, but not CysLT2R(-/-) mice, had abrogated responses.

186 Depletion of either LRRC25 or ISG15 abrogates RIG-I-p62 interaction as well as the autophagi

187 Mechanistically, STAG1 loss abrogates sister chromatid cohesion in STAG2 mutated but

188 ble, and the consequent ability to precisely abrogate specific MMP activity could contribute to the f

189 ) mutation was combined with point mutations abrogating specific phosphorylation sites on KIT.

190 nd we identify a specific Zwilch mutant that abrogates Spindly and dynein recruitment in vivo and Spi

191 Silencing of PECAM-1 or key ER stress genes abrogated SS regulation of VCAM-1 transcription and mono

192 that mutation of these OH-interface residues abrogates starvation-induced up-regulation of autophagy

193 SPR/Cas9 nuclease genome editing, display an abrogated stretch-stimulated actin reinforcement respons

194 Furthermore, MI-2 abrogated survival signals provided by stromal cells and

195 ed TGF-beta or inhibition of exosome release abrogated Tfr expansion.

196 of GLS1 expression, in the presence of Gln, abrogated TGF-beta1-induced expression of profibrotic ma

197 In addition, DMF abrogated TGFbeta/Akt1 mediated inhibitory phosphorylati

198 mplex, a coactivator of transcription, which abrogate the ability to carry out most of these sterol-d

199 We can abrogate the action-at-a-distance signaling of exosomes

200 We found that one of these inhibitors can abrogate the Aha1-induced ATPase stimulation of Hsp90 wi

201 ogenases prevent nitrotyrosine formation and abrogate the cytotoxicity of RNS against phoQ Salmonella

202 fe seizures influence them, and the means to abrogate the ensuing cognitive problems.SIGNIFICANCE STA

203 rabine, and the ability of ATR inhibition to abrogate the G2 cell cycle checkpoint both contributed t

204 example of a strategy used by adenovirus to abrogate the host DDR and show how viruses can modify ce

205 tivity acquired through a common mutation to abrogate the migration of CD8+ T cells to the tumor.

206 the PTEN-null fibroblasts was sufficient to abrogate the observed increase in colony forming activit

207 e tissue by activity of CD39 and, therefore, abrogate the shedding of CD62L.

208 f Mps1 phosphorylation sites in Bub1 or Mad1 abrogate the spindle checkpoint in human cells.

209 hibition of the mechanotransductive pathways abrogated the ability of CAFs to deform the matrix and s

210 Suppression of Mal activity partially abrogated the ability of pico to promote invasion of Ras

211 ion of anti-NKp46 antibodies to TIL cultures abrogated the ability of these regulatory ILCs to suppre

212 the CT26 model, depletion of CD8(+) T cells abrogated the activity of ADCs when used alone or in com

213 In contrast, depletion of endogenous SF3B1 abrogated the apoptotic effects, but not the G2/M cell c

214 FAO inhibition abrogated the ATP rescue, diminished survival of the inn

215 ia-specific depletion of CXCR4/CXCR7 in mice abrogated the chemoattraction of SC to PCC.

216 he recruitment of monocytes to the brain and abrogated the development of anxiety.

217 ed barrier function and circle retention and abrogated the effect of heat stress on longevity.

218 A mixture of bacterial protease inhibitors abrogated the effect of MET-1 effects on DRG neuron rheo

219 ormal and IPF fibroblasts, and antagomiR-630 abrogated the effect of mEV on CDH2 expression.

220 Exogenous administration of HX, GSN, or AAT abrogated the effects of IL-1beta and osteoarthritic syn

221 an alpha5beta1 inhibitor into murine airways abrogated the exaggerated bronchoconstriction induced by

222 downregulated most cytokines and proteases, abrogated the formation of pro- but also anti-inflammato

223 We showed here that E7 abrogated the G1 cell cycle checkpoint under hypoxia and

224 in microvascular perfusion in both legs and abrogated the greater glucose uptake in the exercised co

225 ssion of a PP1c cysteine mutant (C127S-PP1c) abrogated the H2S effect on eIF2alpha phosphorylation.

226 Overexpression of miR-21 abrogated the metformin-mediated inhibition of endotheli

227 Supplemental oxygen administration abrogated the oscillatory shear stress-induced increase

228 ant transgene partially, but not completely, abrogated the phenotype.

229 oth inhibition of AMPK and IL-1R8 deficiency abrogated the positive effects of IL-37 on exercise perf

230 e of the T-cell drivers of allergic immunity abrogated the potential for durable tolerance.

231 Demethylation of DNA abrogated the protective effect of AC whereas remethylat

232 However, combo treatment abrogated the protective effect of transient BAFFR-Fc mo

233 Blockade of CXCR4 abrogated the recruitment of these innate immune cells.

234 sion, inhibited individual cell-motility and abrogated the stem-like phenotype of breast cancer cells

235 WT1 knockdown abrogated the stimulatory effect of SU1498-mediated KDR

236 ated neutralization of galectin-10 partially abrogated the suppressive function of the eosinophils.

237 Blocking caspase-1 activation abrogated the therapeutic effects of the pseudoviruses.

238 he wild-type F427 residue, the K33S mutation abrogates the ability of ectopically expressed GPC to me

239 humans, and genetic deletion of the receptor abrogates the ability of GDF15 to decrease food intake a

240 rasitic helminth infection in mice, and also abrogates the ability of mice to regulate brown fat and

241 Importantly, a T239D or F240D substitution abrogates the activity of GSDMD consisting of amino acid

242 ipitation analysis confirmed that clofibrate abrogates the binding of nuclear factor-kappaB to the PT

243 Thus, deletion of CD36 or Nox2 from PVM abrogates the deleterious vascular effects of Abeta, whe

244 Inducible elimination of integrin alpha5 abrogates the epithelial-organizing effects of P4G11.

245 ' end of the single guide RNA (sgRNA), which abrogates the function of CRISPR-transcriptional activat

246 in any one of the Ndc80p interaction regions abrogates the Ndc80 complex's ability to bind two Dam1 r

247 Functional analyses showed that L35P abrogates the PALB2-BRCA1 interaction and completely dis

248 k stratification and therapy intensification abrogates the poor prognosis of adult ETP-ALL.

249 miR-BART16 abrogates the production of IFN-stimulated genes in resp

250 racerebroventricular injection of clodronate abrogates the reactive oxygen species production and cer

251 Phosphorylation abrogates the scaffold-dependent stimulation of GEF acti

252 armacological inhibition of the MAPK pathway abrogates the stimulus-dependent recruitment of Integrat

253 ctivation of AMPKalpha2, but not AMPKalpha1, abrogates the tumor attenuation caused by UBE2O loss, wh

254 tiple myeloma PC migration toward CCL3 while abrogating the multiple myeloma PC migratory response to

255 neuroblastoma cells, with the E138K mutation abrogating the neurovirulence and neuroinvasiveness of J

256 ing the quorum sensing (QS) mechanism and so abrogating the virulence of the pathogen Streptococcus p

257 region motif of immunodominant MOG peptides abrogated their degradation.

258 g animals under axenic conditions completely abrogates their abnormal phenotype, even upon high-fat d

259 elopment of tertiary lymphoid structures and abrogates their prognostic value in patients with lung c

260 mitochondrially targeted anti-oxidants also abrogate these effects.

261 etter screening and preventive strategies to abrogate these toxic effects and improve patient care.

262 in MSCs using rhodamine 6G pretreatment also abrogated these effects.

263 ne-binding defective mutant of the C2 domain abrogated these properties.

264 Inhibition of DENV RNA replication abrogated these responses.

265 h blocks the pCRP-microvesicle interactions, abrogates these proinflammatory effects.

266 mutations found in multiple myeloma patients abrogate this cytotoxicity, indicating a survival advant

267 ys with human kinesin-5 (Eg5) only partially abrogated this behavior, indicating that Cin8 binds micr

268 th standard of care, eculizumab specifically abrogated this histomolecular rejection phenotype and as

269 n cells with intact KEAP1, and loss of KEAP1 abrogated this increase.

270 pharmacologic blockade of IL-1beta or NLRP3 abrogated this phenotype.

271 Restoring the microbiota of germ-free mice abrogated this protection.

272 hich increases serum 27OHC, or APP ablation, abrogated this response in vivo.

273 4G alone by the human rhinovirus 2A protease abrogated this translation strategy.

274 , and overexpression of VM-inhibiting miRNAs abrogates this upregulation.

275 in fibroblasts, yet targeted tph1b mutations abrogating this response do not disrupt fin regeneration

276 my prevented HSC mobilization and completely abrogated tolerance induction.

277 RG4 disruption abrogates tRNA fragments ability to trigger the formatio

278 MS-444 treatment also abrogated tumor cell apoptosis and depleted tumor-associ

279 silencing Hsp70/90 expression in tumor cells abrogates tumor-induced muscle catabolism and wasting in

280 IGFBP7 abrogates tumors by inhibiting angiogenesis and inducing

281 mutation of any component of the T1SS system abrogated type VI secretion activity under nutrient-limi

282 le-like fibriforms, but this association was abrogated upon microtubule-disassembly agents, resulting

283 n in mouse xenograft models is significantly abrogated upon NRF2 overexpression.

284 y, we showed that this cytotoxicity could be abrogated using CME inhibitors or antioxidants, attestin

285 nectin through anion-exchange chromatography abrogated V2-independent gp120-alpha4beta7 binding.

286 a membrane cholesterol/sphingomyelin balance abrogated vesicle formation.

287 HA is modified by acylation whose removal abrogates viral replication.

288 ntiacanthamoebal chemotherapy by potentially abrogating virulence-enhancing properties of bacterial e

289 p62 by small interfering RNA in MCF-7 cells abrogates Vps34-dependent tumor growth.

290 By hardening the wall, the increased pH abrogates wall loosening required for cell expansion and

291 ant mouse model and that this enhancement is abrogated when mAgrin is in molar excess relative to lam

292 Profibrotic polarization was abrogated when MCU was absent or its activity was blocke

293 helial barrier function, and this effect was abrogated when Rac1 was simultaneously activated.

294 ors since LKB1-silencing and AMPK-inhibition abrogated, while LKB1-overexpression and AMPK-activation

295 ogenin secretion by ARPE-19 cells, which was abrogated with a blue light - blocking filter.

296 iectomized female mice, while the effect was abrogated with estradiol supplementation, suggesting tha

297 es late Na(+) current, two effects that were abrogated with NaV1.5 mutants mimicking phosphorylation

298 d peptide, we show that receptor assembly is abrogated within the plasma membrane.

299 Xist-dependent Polycomb recruitment, in turn abrogating Xist-mediated gene silencing and reversing Xi

300 us, mutation of any of these residues to Ala abrogated zinc transfer from AztD.