ライフサイエンスコーパス: ISA

1 er intervention and at follow-up (persistent ISA).

2 roximately -38.9 cal K(-1) mol(-1) for C136A ISA).

3 t dispersion (IPD) and iris stromal atrophy (ISA).

4 ) develop an iris stromal atrophy phenotype (ISA).

5 s yielded an optimal cutoff value of 55% for ISA.

6 chments only slightly exceeded by memISA and ISA.

7 VUS images were reviewed for the presence of ISA.

8 when appropriate to aim at minimizing acute ISA.

9 </=10 mg and sustained control) with the new ISA.

10 chronic total occlusions might predispose to ISA.

11 tween the filter shapes learned with SSA and ISA.

12 PECT difference analysis was performed using ISAS.

13 can be achieved after switching or combining ISAs.

14 igh potential as a drug target, and compound ISA-2011B is interesting for further development of targ

15 ISA-2011B significantly inhibits growth of tumor cells i

16 alpha exerts similar effects on PC3 cells as ISA-2011B treatment, significantly inhibiting AKT activi

17 able target for our newly developed compound ISA-2011B using a high-throughput KINOMEscan platform.

18 ISA-2011B was discovered during our synthetic studies of

19 u1 physical interacts with components of the ISA [4Fe-4S] assembly complex and client proteins that n

20 d by yMSP1(19) in a formulation of Montanide ISA 51 (ISA) plus CpG ODN 1826 was similar or superior t

21 yrosinase emulsified with adjuvant Montanide ISA 51 and received a fully human anti-cytotoxic T-lymph

22 with HIV Gag protein emulsified in Montanide ISA 51, an oil-based adjuvant, with or without a TLR7/8

23 with incomplete Freund's adjuvant (Montanide ISA 51; Seppic SA, Paris, France).

24 ny-stimulating factor (GM-CSF) and Montanide ISA-51 adjuvant (Seppic Inc, Fairfield, NJ), or pulsed o

25 c when administered with GM-CSF in Montanide ISA-51 adjuvant.

26 eptide epitopes were emulsified in Montanide-ISA-51 and given every 3 weeks with intramuscular polyin

27 plus incomplete Freund's adjuvant (Montanide ISA-51) once per cycle, followed by interleukin-2.

28 with recombinant NY-ESO-1 protein, Montanide ISA-51, and CpG ODN 7909, a potent stimulator of B cells

29 more potent water-in-oil adjuvant Montanide ISA 720 (ICC-1132/ISA 720).

30 are immunization of 5gP protein in Montanide ISA 720 (SEPPIC, Paris, France), an adjuvant recently ap

31 ter membrane protein (MOMP), using Montanide ISA 720 and CpG-1826 as adjuvants.

32 ISA 720 appeared more effective than Freund's against oc

33 Emulsification of the 5gP protein in ISA 720 appeared to be more effective than emulsificatio

34 received either 20 mug or 50 mug of ICC-1132/ISA 720 developed antiimmunogen and anti-HBc antibodies.

35 gle dose of ICC-1132 formulated in Montanide ISA 720 encourage further clinical development of this m

36 antibody following a single injection of the ISA 720 formulated vaccine were comparable to those obta

37 ed with 5gP DNA or 5gP protein emulsified in ISA 720 or Freund's adjuvant.

38 uvanted with either Quil A or with Montanide ISA 720 plus CpG oligodeoxynucleotide (ODN) and was obse

39 ripheral blood mononuclear cells of ICC-1132/ISA 720 vaccinees proliferated and released cytokines (i

40 strain Nigg II using CpG-1826 and Montanide ISA 720 VG as adjuvants.

41 -in-oil adjuvant Montanide ISA 720 (ICC-1132/ISA 720).

42 l-dipeptide as adjuvant emulsified in SEPPIC ISA 720.

43 d rabbits and mice with LSA-NRC in Montanide ISA 720.

44 L. major SEAgs coadministered with Montanide ISA 720.

45 P) plus the adjuvants CpG-1826 and Montanide ISA 720; then they were challenged with C. muridarum.

46 th recombinant Pfs25 formulated in Montanide ISA-720 increased antibody titers (30-fold) and signific

47 calculated by isotopomer spectral analysis (ISA), a nonlinear regression method, did not agree with

48 Biochemical analyses characterized ISA activities in mutant tissues.

49 Three ISA activity forms were observed in leaves, two ISA1/ISA

50 Among these, 12 had ISA after intervention and at follow-up (persistent ISA)

51 ze of the left atrial isolated surface area (ISA) after pulmonary vein antrum isolation for paroxysma

52 We hypothesize that IPD and ISA alter melanosomes, allowing toxic intermediates of p

53 The ISA analyses of MIDs of fatty acids and sterols from liv

54 ne with ISA1 homomer but lacking heteromeric ISA and a second line with one form of ISA1/ISA2 heterom

55 For the ISA and CTS, the prevalence rates were 24.3% (95% CI, 19

56 g distinct binding sites for binding of holo ISA and ISU to apo Fd.

57 g) could ultimately reduce the occurrence of ISA and its potentially harmful consequences.

58 The Tyrpl gene is a candidate for isa and likely causes ISA via a mechanism involving pigm

59 e pooled, inconsistent changes were noted in ISA and LSA (LSA were greater in NIDDM vs. IDDM at basel

60 aper, four clustering methods, CRC, k-means, ISA and memISA, are used upon three brain expression dat

61 ed, or bare, depending on the persistence of ISA and on the coverage.

62 ive values of the PVS were compared with the ISA and the CTS as criterion standards.

63 istributions of the samples were analyzed by ISA and the two-isotopomer method to determine whether e

64 partner violence, the Index of Spouse Abuse (ISA) and the Conflict Tactics Scale (CTS).

65 ss; Landsat-derived impervious surface area (ISA); and Visible Infrared Imaging Radiometer Suite (VII

66 osynthesis were tested, and GBSS, SS, SBEII, ISA, and AGPase were highly expressed in TNN18 and TNG31

67 Greenness, ISA, and NTL were associated with increased SBP, DBP, an

68 based on the "inhibition in solution assay" (ISA) approach using an immobilized target definition com

69 The format and protocol of this quantitative ISA assay can be easily automated to fit into numerous p

70 as 10 microl, is almost impossible, whereas ISA assay detects retroviruses from as small as 1 to 5 m

71 We present here a novel quantitative ISA assay for retroviruses using a replication-defective

72 An ISA assay of a 10-microl viral sample generates results

73 We validated the clinical utility of the MTB-ISAD assay by detecting MTB nucleic acid in sputum sampl

74 The MTB-ISAD assay has improved time-efficiency, affordability,

75 clinical specimens, confirming that the MTB-ISAD assay is fast (<20 min), highly sensitive, accurate

76 We showed the ability of the MTB-ISAD assay to detect MTB in 42 clinical specimens, confi

77 tical for promoting cluster transfer from Sp ISA (at 25 degrees C, k(2) approximately 170 M(-1) min(-

78 thermal solid-phase amplification/detection (ISAD) based on silicon microring biosensor.

79 Forty Isa Brown laying hens (26weeks old) were equally subject

80 However, memISA and ISA can add extra high-quality clusters to the set produ

81 Concentration-dependent ISA, carried out on a subset of 19 potential inhibitors,

82 no negative clinical events reported for any ISA cases at 12-month clinical follow-up.

83 s primarily at the stent edges in persistent ISA cases, whereas late-acquired ISA in SES occurred mos

84 y be a critical component of somatodendritic ISA channels in the brain.

85 its that associate with Kv4 subunits to form ISA channels in vivo.

86 ritic subthreshold A-type potassium current (ISA) channels.

87 explored a microscopy-based single-molecule ISA compatible with liposome-reconstituted membrane prot

88 ndosperm contained three high molecular mass ISA complexes resolved by gel permeation chromatography

89 ent with the protein compositions, all three ISA complexes were missing in an ISA1-null line, whereas

90 riod visual experience on the development of ISA correlation and latency patterns within and across c

91 Minor variations in rate constant for the ISA Cys derivatives do not reflect any change in the aff

92 reaction for the wild type versus this C136A ISA derivative is distinct (DeltaH* approximately 6.3 kc

93 very low density lipoprotein by a variant of ISA designed to detect gradients in precursor enrichment

94 Malapposed segments with an ISA detachment <100 mum at baseline showed complete stru

95 d strut malapposed with moderate detachment (ISA detachment distance <100 mum) have minimal disturban

96 t follow-up, whereas segments with a maximal ISA detachment distance of 100 to 300 mum and >300 mum h

97 of delayed strut coverage both increase with ISA detachment distance.

98 nt or absent) and to define the threshold of ISA detachment that might benefit from optimization duri

99 omozygous for the D2 alleles of both ipd and isa develop an earlier onset and more severe disease inv

100 of a different locus on chromosome 4 (called isa) develop an iris stromal atrophy phenotype (ISA).

101 tic mobility of recombinant and native maize ISA differed, suggestive of posttranslational modificati

102 d an important impact of baseline strut-wall ISA distance on the risk of incomplete strut coverage at

103 ISA size (estimated as ISA volume or maximum ISA distance per strut) was an independent predictor of

104 ith floating strut that has more significant ISA distance.

105 Inhibition-in-solution assays (ISA) employing surface-based biosensors such as surface

106 arily in the converted croplands) because of ISA expansion from 1990 to 2010.

107 patterns of SOCISA and mapped the impact of ISA expansion on SOC storage.

108 The impacts of the ISA expansion varied spatially, depending on the land- u

109 ability to assess the ecological impacts of ISA expansion.

110 with Kv4 and KChIP at the plasma membrane of ISA -expressing neuron somata supports the existence of

111 tence of Kv4/KChIP/DPPL ternary complexes in ISA -expressing nociceptors and pain-modulating spinal i

112 P and DPPL are coexpressed with Kv4 in these ISA -expressing pain-related neurons is unknown.

113 The average ISA for all patients was 59.2+/-11.6%.

114 ights repository, powered by the open source ISA framework, is cross-species and cross-technique.

115 nd dicots is responsible for distinctions in ISA function.

116 ISA functions were characterized in maize (Zea mays) lea

117 ents were divided into 4 groups according to ISA (group I: <50%; group II: 50 to <60%; group III: 60

118 ISA>/=55% may thus serve as a predictor for long-term su

119 Segments with acute ISA had higher risk of delayed coverage than well-appose

120 Late-acquired ISA has been reported in bare-metal stents (BMS) and bra

121 Incomplete stent apposition (ISA) has been observed frequently in patients with very

122 debranching enzyme activity present is ISA1/ISA heteromer.

123 This is supported by the rescue of IPD and ISA in D2 eyes with substantially decreased pigment prod

124 However, the characteristics of late ISA in SES have not been clarified.

125 persistent ISA cases, whereas late-acquired ISA in SES occurred mostly in the mid portion of the ste

126 ing stent implantation, suggesting a role of ISA in the pathogenesis of this adverse event.

127 characterize the vascular response to acute ISA in vivo and to look for predictors of incomplete hea

128 he frequency of incomplete stent apposition (ISA) in sirolimus-eluting stents (SES) and clarify its f

129 ed with an independent system approximation (ISA), including proteins.

130 isoamylase-type starch debranching enzymes (ISAs), including the catalytic ISA1 and noncatalytic ISA

131 The accurate diagnosis of ISA, initially only possible with intravascular ultrasou

132 the presence of insulin-specific antibodies (ISA), insulin lispro-specific antibodies (LSA), and cros

133 ISA is caused by the recessive Tyrp1b mutant allele and

134 icating that either homomeric or heteromeric ISA is competent for starch biosynthesis.

135 f the matrix method, we demonstrate that the ISA is not valid for the title compound.

136 Immobilized sample amplification (ISA) is a novel method for amplification, detection, mon

137 Incomplete stent apposition (ISA) is characterized by the lack of contact of at least

138 action to acute incomplete stent apposition (ISA) is not well known.

139 anization of spontaneous infraslow activity (ISA) is plastic in that it can be modulated by learning

140 g clusters produced by k-means and memISA or ISA leads to increased GO enrichment and number of clust

141 afficking and reconstituting native neuronal ISA-like properties.

142 An inspection of Isa-like proteins from bacteria to mammals revealed thre

143 nificant differences were noted over time in ISA, LSA, or CRA attributable to the type of short-actin

144 ance to the chemotherapeutic agent cisplatin isa major limitation for the successful treatment of ova

145 Since the ISA method eliminates the isolation/extraction of the nu

146 The isa mutant accumulates primarily phytoglycogen in leaf m

147 centration was significantly elevated in the isa mutants, and the activities of the Fe-S cluster-cont

148 are while decreasing the cost of health care isa national priority.

149 juvant, 0 of 4 (0%) with CpG 1826 mixed with ISA (no yMSP1(19)), and 0 of 11 (0%) with CpG 1826 alone

150 Thus, a function of heteromeric ISA not compensated for by homomeric enzyme affects gran

151 ormal starch characteristics, in contrast to ISA-null lines, indicating that either homomeric or hete

152 dure and to vascular healing might influence ISA occurrence.

153 Residing in areas with higher ISA or NTL, or lower greenness, was significantly associ

154 g used (second-line immunosuppressive agent [ISA] or biologicals), and drug doses were obtained.

155 in mice to examine whole-cortex spontaneous ISA patterns.

156 gle time point assessments comparing overall ISA percentage and magnitude in different groups (i.e.,

157 e per strut) was an independent predictor of ISA persistence and of delayed healing at follow-up.

158 Isoamylase-type starch debranching enzymes (ISA) play important roles in starch biosynthesis in chlo

159 unized with yMSP1(19), 22 of 32 (68.7%) with ISA plus CpG 1826, 0 of 4 (0%) with CFA/incomplete Freun

160 P1(19) in a formulation of Montanide ISA 51 (ISA) plus CpG ODN 1826 was similar or superior to that c

161 nipulation of Tmprss6 with RNAi therapeutics isa practical approach to treating iron overload disease

162 Substitution of the cysteine residues of ISA produced derivative proteins (C72A, C136A, and C138A

163 f isoamylase-type starch-debranching enzyme (ISA) proteins and complexes in maize (Zea mays) endosper

164 rience induces global changes in spontaneous ISA relationships, both within the visual network and ac

165 sis (MIDA) and isotopomer spectral analysis (ISA) represent such methods and are based on the combina

166 nctional genetic tests, we show that IPD and ISA result from mutations in related genes encoding mela

167 Subthreshold A-type K(+) currents (ISA s) have been recorded from the cell bodies of hippoc

168 Subthreshold A-type K(+) currents (ISA s) have been recorded from the somata of nociceptors

169 nels are responsible for the somatodendritic ISA s.

170 nels are responsible for the somatodendritic ISA s.

171 ISA screening, carried out on the Prestwick Chemical Lib

172 rface-bound partner is optimal for SPR-based ISA screening.

173 Coverage of ISA segments is delayed with respect to well-apposed seg

174 The morphological pattern of healing in the ISA segments was categorized as homogeneous, layered, cr

175 me decreased significantly, and 71.5% of the ISA segments were completely integrated into the vessel

176 evaluate the impact of different degrees of ISA severity on abnormal shear rate and healing response

177 component chromophores, the validity of the ISA should never be taken for granted and the effective

178 Acute ISA size (estimated as ISA volume or maximum ISA distanc

179 e paucity of field observations on SOC under ISA (SOCISA), especially in dryland areas has limited ou

180 ic tool that may serve as a component of the ISA software suite.

181 rate, ca. 10 samplesh(-1), mobile phase and ISA solution consumption, ca. 2.6 mL per analysis, and C

182 experiments can be exported in the standard ISA-Tab format for deposition in public databases.

183 ing instrument and acquisition parameters in ISA-Tab format on users, who have to do it manually, a p

184 hon packages that can automatically generate ISA-Tab metadata file stubs from raw XML metabolomics da

185 n the multi-omics Investigation/Study/Assay (ISA-Tab) format and can be queried in the data repositor

186 mal solid-phase amplification/detection (MTB-ISAD), that couples isothermal solid-phase amplification

187 The larger the acute ISA, the greater the likelihood of persistent malapposit

188 Compared with the ISA, the sensitivity of the PVS in detecting partner abu

189 In late-acquired ISA, there was an increase in external elastic membrane

190 rapid expansion of impervious surface areas (ISA) threatens soil organic carbon (SOC) pools in urbani

191 ty-five episodes involved switching from one ISA to another, with 50% to 100% of these patients achie

192 ster transfer from Schizosaccharomyces pombe ISA to apo Fd.

193 l histopathology and clinical studies linked ISA to stent thrombosis, potential selection bias preclu

194 ce (SPR)-based inhibition in solution assay (ISA) to search for inhibitors of the medium affinity (KD

195 debranching enzyme ISOAMYLASE1-ISOAMYLASE2 (ISA; to alter branching pattern).

196 se studies and implementations at http://www.isa-tools.org.

197 mentation are available at http://github.com/ISA-tools/graph2tab.

198 entation and examples at: https://github.com/ISA-tools/OntoMaton.

199 ISA type proteins mediate cluster transfer to apoprotein

200 ttp://grimmond.imb.uq.edu.au/uniqueome/; the ISAS uniqueome aligner is freely available from http://w

201 ISA uses all mass isotopomers, correctly identified impo

202 lusion of CpG ODN 1826 in the yMSP1(19) plus ISA vaccine contributed towards the induction of higher

203 ene is a candidate for isa and likely causes ISA via a mechanism involving pigment production.

204 luate their transcriptomic regulation during ISA virus (ISAV) infection, an Orthomyxoviridae virus as

205 Most were similarly regulated in response to ISA virus infection; (ii) The transcript subsets were un

206 After 6 months, acute ISA volume decreased significantly, and 71.5% of the ISA

207 Acute ISA size (estimated as ISA volume or maximum ISA distance per strut) was an ind

208 Subgroup analysis showed that ISA was 42.8+/-4.2% in group I (n=23), 54.2+/-3.0% in gr

209 After 12 months, a larger ISA was associated with a significantly lower AF and mac

210 The ISA was defined as the ratio of the total isolated antra

211 Late ISA was observed in 8.7% of patients after SES implantat

212 Late-acquired ISA was seen in the remaining seven cases, all from the

213 n NIDDM vs. IDDM at baseline, P = 0.001, and ISA were greater in IDDM vs. NIDDM at 6 months, P = 0.00

214 Seventy-eight segments with acute ISA were identified in 36 of the patients and matched wi

215 A combination of ISAs were used in 53 episodes, with "success" being achi

216 nts had LSA (0-4%) and approximately 10% had ISA, whereas 41-45% of patients with IDDM and 23-27% of

217 and shear distribution in different cases of ISA with increasing strut-wall detachment distance (rang

218 tly parallels independent subspace analysis (ISA) with the only difference that SSA maximizes slownes

219 was found to be similar for native and C136A ISA, with an observed pK(a) of 7.8 determined from the p

220 Neointimal healing tends to reduce ISA, with the malapposed stent struts often integrated c