Facile oxidation of aldehydes to acids and esters with Oxone

Org Lett. 2003 Apr 3;5(7):1031-4. doi: 10.1021/ol0340078.

Abstract

[reaction: see text] A highly efficient, mild, and simple protocol is presented for the oxidation of aldehydes to carboxylic acids utilizing Oxone as the sole oxidant. Direct conversion of aldehydes in alcoholic solvents to their corresponding ester products is also reported. These reactions may prove to be valuable alternatives to traditional metal-mediated oxidations.