メタボリックシンドロームの概念のいわば前身で、上半身肥満、糖代謝異常（糖尿病）、高中性脂肪血症（高脂血症）、高血圧が合併した状態をさします。1989年にアメリカの研究者カプラン（Kaplan NM）によって提唱され、冠動脈疾患による死亡率が高く、まさに死の序曲を奏でるという意味合いから「死の四重奏（The Deadly Quartet）」と呼ばれました。
メタボリックシンドロームの概念との違いが曖昧に紹介されることがよくありますが、メタボリックシンドロームでは糖代謝異常、脂質代謝異常、高血圧の上流に、それらの原因として内臓脂肪蓄積を置いている点が大きく異なります。
メタボリックシンドロームは、この死の四重奏をはじめ、シンドロームX、インスリン抵抗性症候群、マルチプルリスクファクター症候群などの一連の概念を最終的に整理したものといえます。尚、特定健診・特定保健指導では、メタボリックシンドロームの和名表記の同義語として「内臓脂肪症候群」の呼称を用いています。
し‐の‐しじゅうそう〔‐シヂユウソウ〕【死の四重奏】
死の四重奏
読み方：しのよんじゅうそう
別名：インスリン抵抗性症候群,マルチプルリスクファクター症候群,内臓脂肪症候群,危険因子集積症候群,メタボリックシンドローム
【英】：シンドロームX
別名：インスリン抵抗性症候群,マルチプルリスクファクター症候群,内臓脂肪症候群,危険因子集積症候群,メタボリックシンドローム
【英】：シンドロームX
メタボリックシンドローム
(死の四重奏 から転送)
出典: フリー百科事典『ウィキペディア（Wikipedia）』 (2023/07/22 07:46 UTC 版)
メタボリックシンドローム（英: Metabolic syndrome）とは、内臓脂肪型肥満（内臓肥満・腹部肥満）に高血糖・高血圧・脂質異常症のうち2つ以上の症状が一度に出ている状態をいう。日本語に訳すと代謝症候群という。単にメタボとも言われる。
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[続きの解説]
「メタボリックシンドローム」の続きの解説一覧
- 1 メタボリックシンドロームとは
- 2 メタボリックシンドロームの概要
- 3 診断基準
- 4 脚注
死の四重奏
- 死の四重奏のページへのリンク
