リデリイン
出典: フリー百科事典『ウィキペディア（Wikipedia）』 (2023/01/01 08:12 UTC 版)
リデリイン（英: riddelliine）は、ピロリジジンアルカロイドに分類される化合物である。Senecio riddelliiから初めて単離され[1]、ヤコブボロギク、ノボロギク、その他のキオン属等の様々な植物でも見られる。
- ^ a b Adams, I. Roger; Hamlin, K. E., Jr.; Jelinek, C. F.; Phillips, R. F. (1942). “Structure of riddelliine, the alkaloid in Senecio riddellii ”. Journal of the American Chemical Society 64 (12): 2760–2763. doi:10.1021/ja01264a013.
- ^ NTP Technical Report on Toxicity Studies of Riddelliine Archived 2011-10-23 at the Wayback Machine., National Toxicology Program, Toxicity Report Series, Number 27
- ^ National Toxicology, Program (2003). “Toxicology and carcinogenesis studies of riddelliine (CAS No. 23246-96-0) in F344/N rats and B6C3F1 mice (gavage studies)”. National Toxicology Program Technical Report Series (508): 1–280. PMID 12844193.
- ^ 12th Report on Carcinogens Archived 2011-06-25 at the Wayback Machine., National Toxicology Program
- ^ a b c d e f g h Chan, Po (December 1993). “NTP technical report on the toxicity studies of Riddelliine (CAS No. 23246-96-0) Administered by Gavage to F344 Rats and B6C3F1 Mice”. Toxicity Report Series 27: 1–D9. ISSN 1521-4621. PMID 12209179.
- ^ a b Manske, Richard H. F. (1939-01-01). “The Alkaloids of Senecio Species: Iii. Senecio Integerrimus, S. Longilobus, S. Spartioides and S. Ridellii”. Canadian Journal of Research 17b (1): 1–7. doi:10.1139/cjr39b-001. ISSN 1923-4287.
- ^ “Riddelliine”. Report on Carcinogens. 2018年12月4日閲覧。
- ^ “Journal of the Chemical Society, Chemical Communications”. Journal of the Chemical Society, Chemical Communications. doi:10.1039/0022-4936/1972.
- ^ a b Chou, Ming W.; Jian, Yan; Williams, Lee D.; Xia, Qingsu; Churchwell, Mona; Doerge, Daniel R.; Fu, Peter P. (2003-09-01). “Identification of DNA Adducts Derived from Riddelliine, a Carcinogenic Pyrrolizidine Alkaloid”. Chemical Research in Toxicology 16 (9): 1130–1137. doi:10.1021/tx030018y. ISSN 0893-228X. PMID 12971801.
- ^ Williams, L.; Chou, M. W.; Yan, J.; Young, J. F.; Chan, P. C.; Doerge, D. R. (2002-07-15). “Toxicokinetics of Riddelliine, a Carcinogenic Pyrrolizidine Alkaloid, and Metabolites in Rats and Mice”. Toxicology and Applied Pharmacology 182 (2): 98–104. doi:10.1006/taap.2002.9441. ISSN 0041-008X. PMID 12140173.
- ^ a b Mei, Nan; Guo, Lei; Liu, Ruqing; Fuscoe, James C.; Chen, Tao (2007-11-01). “Gene expression changes induced by the tumorigenic pyrrolizidine alkaloid riddelliine in liver of Big Blue rats”. BMC Bioinformatics 8 (7): S4. doi:10.1186/1471-2105-8-S7-S4. ISSN 1471-2105. PMC 2099496. PMID 18047727.
- ^ a b c d e f Official., Publication, IARC (2002). Some Traditional Herbal Medicines, Some Mycotoxins, Naphthalene and Styrene.. Geneva: World Health Organization. ISBN 9789283215899. OCLC 476191138
- ^ Chan, Po C.; Haseman, Joseph K.; Prejean, J. D.; Nyska, Abraham (2003-10-15). “Toxicity and carcinogenicity of riddelliine in rats and mice”. Toxicology Letters 144 (3): 295–311. doi:10.1016/S0378-4274(03)00240-6. ISSN 0378-4274. PMID 12927348.
- ^ Wang, Yu-Ping; Fu, Peter P.; Chou, Ming W. (May 2005). “Metabolic Activation of the Tumorigenic Pyrrolizidine Alkaloid, Retrorsine, Leading to DNA Adduct Formation In Vivo”. International Journal of Environmental Research and Public Health 2 (1): 74–79. doi:10.3390/ijerph2005010074. ISSN 1661-7827. PMC 3814699. PMID 16705803.
- ^ Johnson, A. E.; Molyneux, R. J.; Stuart, L. D. (March 1985). “Toxicity of Riddell's groundsel (Senecio riddellii) to cattle”. American Journal of Veterinary Research 46 (3): 577–582. ISSN 0002-9645. PMID 3994126.
[続きの解説]
「リデリイン」の続きの解説一覧
- 1 リデリインとは
- 2 リデリインの概要
- 3 機構
- 4 歴史
- リデリインのページへのリンク
