プロスタグランディン
プロスタグランジン【prostaglandin】
プロスタグランジン
プロスタグランジン
プロスタグランジン エンドペルオキシド
アラキドン酸からプロスタグランジン群やトロンボキサンを生合成する前駆体 これらは生理学的にも活性な化合物で、血管や気道平滑筋、血小板凝集などに影響を与える。もっとも良く見られるのはプロスタグランジンH2である。
名前 | Prostaglandin H2 |
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Prostaglandin H2 - アラキドン酸からシクロオキシゲナーゼによる反応で得られる環状エンドペルオキシド中間体で、ここからさらに一連の酵素反応によって2種類のプロスタグランジンへ変換される。(MeSH: 68044262)
プロスタグランジンA
プロスタグランジンD
プロスタグランジンF
プロスタグランジンI
Prostaglandins - MeSH
- Prostaglandin Endoperoxides
Precursors in the biosynthesis of prostaglandins and thromboxanes from arachidonic acid. They are physiologically active compounds, having effect on vascular and airway smooth muscles, platelet aggregation, etc. Year introduced: 1978- Prostaglandins G
A group of physiologically active prostaglandin endoperoxides. They are precursors in the biosynthesis of prostaglandins and thromboxanes. Most frequently encountered member of this group is the prostaglandin G2. Year introduced: 1991(1978) - Prostaglandins H+
A group of physiologically active prostaglandin endoperoxides. They are precursors in the biosynthesis of prostaglandins and thromboxanes. The most frequently encountered member of this group is the prostaglandin H2. Year introduced: 1991(1978)
- Prostaglandins A
(13E,15S)-15-Hydroxy-9-oxoprosta-10,13-dien-1-oic acid (PGA(1)); (5Z,13E,15S)-15-hydroxy-9-oxoprosta-5,10,13-trien-1-oic acid (PGA(2)); (5Z,13E,15S,17Z)-15-hydroxy-9-oxoprosta-5,10,13,17-tetraen-1-oic acid (PGA(3)). A group of naturally occurring secondary prostaglandins derived from PGE; PGA(1) and PGA(2) as well as their 19-hydroxy derivatives are found in many organs and tissues. Year introduced: 1975 - Prostaglandins B
Physiologically active prostaglandins found in many tissues and organs. They are potent pressor substances and have many other physiological activities. Year introduced: 1991(1978) - Prostaglandins D
Physiologically active prostaglandins found in many tissues and organs. They show pressor activity, are mediators of inflammation, and have potential antithrombotic effects. Year introduced: 1984(1978)- Prostaglandin D2
The principal cyclooxygenase metabolite of arachidonic acid. It is released upon activation of mast cells and is also synthesized by alveolar macrophages. Among its many biological actions, the most important are its bronchoconstrictor, platelet-activating-factor-inhibitory, and cytotoxic effects. Year introduced: 1989
- Prostaglandins E
(11 alpha,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-en-1-oic acid (PGE(1)); (5Z,11 alpha,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid (PGE(2)); and (5Z,11 alpha,13E,15S,17Z)-11,15-dihydroxy-9-oxoprosta-5,13,17-trien-1-oic acid (PGE(3)). Three of the six naturally occurring prostaglandins. They are considered primary in that no one is derived from another in living organisms. Originally isolated from sheep seminal fluid and vesicles, they are found in many organs and tissues and play a major role in mediating various physiological activities. Year introduced: 1975- Dinoprostone
A naturally occurring prostaglandin that has oxytocic, luteolytic, and abortifacient activities. Due to its vasocontractile properties, the compound has a variety of other biological actions. Year introduced: 1989
- Prostaglandins F
(9 alpha,11 alpha,13E,15S)-9,11,15-Trihydroxyprost-13-en-1-oic acid (PGF(1 alpha)); (5Z,9 alpha,11,alpha,13E,15S)-9,11,15-trihydroxyprosta-5,13-dien-1-oic acid (PGF(2 alpha)); (5Z,9 alpha,11 alpha,13E,15S,17Z)-9,11,15-trihydroxyprosta-5,13,17-trien-1-oic acid (PGF(3 alpha)). A family of prostaglandins that includes three of the six naturally occurring prostaglandins. All naturally occurring PGF have an alpha configuration at the 9-carbon position. They stimulate uterine and bronchial smooth muscle and are often used as oxytocics. Year introduced: 1975- 6-Ketoprostaglandin F1 alpha
The physiologically active and stable hydrolysis product of EPOPROSTENOL. Found in nearly all mammalian tissue. Year introduced: 1982 - Dinoprost
A naturally occurring prostaglandin that has oxytocic, luteolytic, and abortifacient activities. Due to its vasocontractile properties, the compound has a variety of other biological actions.Year introduced: 1989
- Prostaglandins I
A class of cyclic prostaglandins that contain the 6,9-epoxy bond. Endogenous members of this family are biosynthesized enzymatically from PROSTAGLANDIN ENDOPEROXIDES. Year introduced: 2004- Epoprostenol
A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from PROSTAGLANDIN ENDOPEROXIDES in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension (HYPERTENSION, PULMONARY). Year introduced: 1991(1978)
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プロスタグランジン
プロスタグランジン
出典: フリー百科事典『ウィキペディア(Wikipedia)』 (2021/11/15 14:07 UTC 版)
プロスタグランジン (prostaglandin, PG) は、プロスタン酸骨格をもつ一群の生理活性物質[1]。アラキドン酸から生合成されるエイコサノイドの 1 つで、様々な強い生理活性を持つ。プロスタグランジンとトロンボキサンを合わせてプロスタノイドという。
- ^ IUPAC Gold Book - prostaglandins
- ^ a b 酒井浄「プロスタグランディンの化学」『有機合成化学協会誌』第29巻第3号、有機合成化学協会、1979年、 205-226頁、 doi:10.5059/yukigoseikyokaishi.29.205。
- 1 プロスタグランジンとは
- 2 プロスタグランジンの概要
- 3 関連項目
「プロスタグランジン」の例文・使い方・用例・文例
プロスタグランジンと同じ種類の言葉
固有名詞の分類
- プロスタグランジンのページへのリンク